Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14570493 | 0.86 | IDO1 (0.43) | IDO1RAPGEF4GRIN2BNOS3NOS1 | |
| SCHEMBL26074528 | 0.86 | IDO1 (0.46) | IDO1DAONOTUMHTR2AHTR2B | |
| SCHEMBL148275 | 0.86 | IDO1 (0.52) | IDO1DAONOTUMHTR2AHTR2B | |
| SCHEMBL14612469 | 0.85 | HSPA5 (0.35) | RAPGEF4GRIN2BIDH1PGK1PGK2 | |
| SCHEMBL16767879 | 0.84 | GRIN2B (0.44) | IDO1RAPGEF4GRIN2BNOS3NOS1 | |
| SCHEMBL13983514 | 0.83 | NOS1 (0.43) | IDO1RAPGEF4GRIN2BNOS3NOS1 | |
| SCHEMBL16703940 | 0.83 | GRIN2B (0.34) | RAPGEF4GRIN2BIDH1PGK1PGK2 | |
| SCHEMBL806121 | 0.83 | IDO1 (0.41) | IDO1RAPGEF4GRIN2BNOS3NOS1 | |
| SCHEMBL799078 | 0.81 | IDO1 (0.39) | IDO1RAPGEF4GRIN2BNOS3NOS1 | |
| SCHEMBL799344 | 0.81 | RXRA (0.45) | IDO1RAPGEF4GRIN2BNOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381112-A1 | Compositions and Methods of Manufacturing Amphiphilic Block Copolymers that Form Nanoparticles in Situ | VACCITECH NORTH AMERICA, INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230337520-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230265054-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2023-08-24 | — | — | US | disclosed |
| US-20230137110-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2023-05-04 | — | — | US | disclosed |
| US-20220267300-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2022-08-25 | — | — | US | disclosed |
| US-20220140252-A1 | NOVEL ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2022-05-05 | — | — | US | disclosed |
| US-20220020935-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2022-01-20 | — | — | US | disclosed |
| US-20210040087-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-02-11 | — | — | US | disclosed |
| WO-2020249669-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2020-12-17 | — | — | WO | disclosed |
| US-10820591-B2 | Substituted sulfonyl amides for controlling animal pests | BAYER AKTIENGESELLSCHAFT (DE) | 2020-11-03 | — | — | US | disclosed |
| US-20110251238-A1 | PPAR AGONIST COMPOSITIONS AND METHODS OF USE | BIOPHARMED (FR) | 2011-10-13 | — | — | US | disclosed |
| US-20110218160-A1 | ARYLALKYLAMINE COMPOUND AND PROCESS FOR PREPARING THE SAME | MIYAZAKI HIROSHI | 2011-09-08 | — | — | US | disclosed |
| US-7781443-B2 | cholesteryl ester transfer protein (CETP) anatgonists such as 2R,4S)-4-{[3,5-Bis(trifluoromethyl)benzyl]-[5-(morpholin-4-yl)pyrimidin-2-yl]}amino-2-ethyl-6-methoxy-3,4-dihydro-2H-[1,5]naphthyridine-1-carboxylic acid ethyl ester, having improved bioavailability | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-08-24 | — | — | US | disclosed |
| US-7781443-B2 | cholesteryl ester transfer protein (CETP) anatgonists such as 2R,4S)-4-{[3,5-Bis(trifluoromethyl)benzyl]-[5-(morpholin-4-yl)pyrimidin-2-yl]}amino-2-ethyl-6-methoxy-3,4-dihydro-2H-[1,5]naphthyridine-1-carboxylic acid ethyl ester, having improved bioavailability | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-08-24 | — | — | US | disclosed |
| US-20090023729-A1 | Trisubstituted amine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-1501791-B1 | AMINO ACID ANALOGUES | BAKER MED RES INST (AU) | 2009-01-21 | — | — | EP | disclosed |
| EP-2003509-A2 | Pattern forming method | FUJIFILM Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |
| US-20070032485-A1 | Tetrahydronaphthyridine derivatives and a process for preparing the same | TANABE SEIYAKU CO., LTD. | 2007-02-08 | — | — | US | disclosed |
| US-20070032485-A1 | Tetrahydronaphthyridine derivatives and a process for preparing the same | TANABE SEIYAKU CO., LTD. | 2007-02-08 | — | — | US | disclosed |
| WO-2005058869-A1 | AMINOBENZIMIDAZOLES AND BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230137110-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF | SLCO2B1, SLCO2A1, SLCO1B3 | IDO1 2340/4885RAPGEF4 4038/4885GRIN2B 820/4885 |
| US-20110251238-A1 | PPAR AGONIST COMPOSITIONS AND METHODS OF USE | PPARA, PPARG, PPARD | IDO1 4369/4885RAPGEF4 1488/4885GRIN2B 619/4885 |
| US-20110218160-A1 | ARYLALKYLAMINE COMPOUND AND PROCESS FOR PREPARING THE SAME | CASR, CNR1, CNR2 | IDO1 1610/4885RAPGEF4 1774/4885GRIN2B 987/4885 |
| US-20230265054-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | SHH, GLI1, SMO | IDO1 2300/4885RAPGEF4 661/4885GRIN2B 3245/4885 |
| US-20220267300-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | IL1B, IL1A, CASP1 | IDO1 261/4885RAPGEF4 3604/4885GRIN2B 3944/4885 |
| US-20220140252-A1 | NOVEL ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LEF1, PIEZO1, L1CAM | IDO1 1278/4885RAPGEF4 2402/4885GRIN2B 924/4885 |
| US-20230337520-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LBR, LPO, LPL | IDO1 1354/4885RAPGEF4 1609/4885GRIN2B 695/4885 |
| US-20210040087-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | SSTR5, SSTR2, SSTR4 | IDO1 1803/4885RAPGEF4 1072/4885GRIN2B 831/4885 |
| US-20070032485-A1 | Tetrahydronaphthyridine derivatives and a process for preparing the same | CETP, MTTP, NPC1L1 | IDO1 4829/4885RAPGEF4 4020/4885GRIN2B 2993/4885 |
| US-10820591-B2 | Substituted sulfonyl amides for controlling animal pests | MLYCD, STOM, DDT | IDO1 2647/4885RAPGEF4 3220/4885GRIN2B 2794/4885 |
| US-20230381112-A1 | Compositions and Methods of Manufacturing Amphiphilic Block Copolymers that Form Nanoparticles in Situ | SBDS, MTDH, DLST | IDO1 3936/4885RAPGEF4 4640/4885GRIN2B 1750/4885 |
| US-20090023729-A1 | Trisubstituted amine compound | CETP, MTTP, APOB | IDO1 3561/4885RAPGEF4 4815/4885GRIN2B 4198/4885 |
| US-20220020935-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD1, OCIAD2, LEF1 | IDO1 1637/4885RAPGEF4 880/4885GRIN2B 2689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.