Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Rhodamine 6G. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.34 |
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.34 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.33 |
| ▸ | JAK2 known ✓ | O60674 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rhodamine 6G SCHEMBL7765501 | 0.99 | ABCB1 (0.35) | USP2CFTRPAX8ATMGOPC | |
| Rhodamine 6G SCHEMBL4218403 | 0.96 | USP2 (0.37) | USP2CFTRPAX8ATMGOPC | |
| Rhodamine 6G SCHEMBL5606069 | 0.96 | USP2 (0.38) | USP2CFTRPAX8ATMGOPC | |
| Rhodamine 6G SCHEMBL5403477 | 0.96 | USP2 (0.38) | USP2CFTRPAX8ATMGOPC | |
| Rhodamine 6G SCHEMBL15348373 | 0.96 | USP2 (0.38) | USP2CFTRPAX8ATMGOPC | |
| Rhodamine 6G SCHEMBL23064834 | 0.96 | USP2 (0.38) | USP2CFTRPAX8ATMGOPC | |
| Rhodamine 6G SCHEMBL23064835 | 0.96 | USP2 (0.38) | USP2CFTRPAX8ATMGOPC | |
| Rhodamine 6G SCHEMBL58076 | 0.96 | USP2 (0.38) | USP2CFTRPAX8ATMGOPC | |
| Rhodamine 6G SCHEMBL8647391 | 0.95 | USP2 (0.38) | USP2CFTRPAX8ATMGOPC | |
| Rhodamine 6G SCHEMBL4817749 | 0.95 | ABCB1 (0.38) | USP2CFTRPAX8ATMGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115216816-A | Copper electroplating solution suitable for copper filling of blind holes of printed circuit board | 哈尔滨工业大学 | 2022-10-21 | — | — | CN | claimed |
| US-6544321-B1 | Using polyoxyalkylene glycol solution | XEROX CORPORATION | 2003-04-08 | — | — | US | claimed |
| EP-0448923-B1 | Method and apparatus for detecting biological activities in a specimen | AVL PHOTRONICS CORP (US) | 1996-01-03 | — | — | EP | claimed |
| US-5372936-A | Exposing sealed container with mixture of sample and culture medium to light, detecting fluorescence emitted by fluorophore in attached sensor, dispersing indicator in container which modulates fluorescence according to concentration change | AVL PHOTORONICS CORPORATION (US) | 1994-12-13 | — | — | US | claimed |
| CN-1087109-A | One group of chemiluminescent mixture system | JIN CHAOYANG (CN) | 1994-05-25 | — | — | CN | claimed |
| US-5266486-A | Monitoring concentration of substance produced or consumed by metabolic processes using indicator which modulates wavelength of radiation emitted by inert fluorophore | NVL PHOTRONICS CORPORATION (US) | 1993-11-30 | — | — | US | claimed |
| EP-0448923-A1 | Method and apparatus for detecting biological activities in a specimen | AVL PHOTRONICS CORPORATION (US) | 1991-10-02 | — | — | EP | claimed |
| US-4877495-A | ALTERNATING CURRENT; CATIONIC DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-10-31 | — | — | US | claimed |
| EP-3965738-B1 | METHOD FOR PRODUCTION OF LIPOSOMES | UNIV DO MINHO (PT) | 2025-08-06 | — | — | EP | disclosed |
| EP-4476529-A1 | SYSTEMS AND METHODS OF BACTERIAL GROWTH DETECTION USING DUAL LIGHT EXCITATION | Becton, Dickinson and Company (US) | 2024-12-18 | — | — | EP | disclosed |
| US-20240393246-A1 | SYSTEMS AND METHODS OF BACTERIAL GROWTH DETECTION USING DUAL LIGHT EXCITATION | BECTON DICKINSON CO (US) | 2024-11-28 | — | — | US | disclosed |
| CN-118661092-A | Systems and methods for bacterial growth detection using dual light excitation | 贝克顿·迪金森公司 | 2024-09-17 | — | — | CN | disclosed |
| US-11946865-B2 | Systems and methods for normalizing signals in blood culture measurement systems | BECTON, DICKINSON AND COMPANY (US) | 2024-04-02 | — | — | US | disclosed |
| US-20240076500-A1 | POLYMERIC DYES AND USES THEREOF | BECTON DICKINSON CO (US) | 2024-03-07 | — | — | US | disclosed |
| US-4425029-A | Fluorescent liquid crystal display devices | SHARP KABUSHIKI KAISHA (JP) | 1984-01-10 | — | — | US | disclosed |
| US-4338213-A | Aqueous chemiluminescent systems | AMERICAN CYANAMID COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| EP-0034261-A2 | Aqueous chemiluminescent systems | AMERICAN CYANAMID COMPANY (US) | 1981-08-26 | — | — | EP | disclosed |
| US-4282357-A | SALTS OF N,N'-BIS(MORPHOLINO- OR PYRIDYLALKYL)-N,N'-BIS(TRIFLUOROMETHYLSULFONYL)OXAMIDES | AMERICAN CYANAMID COMPANY (US) | 1981-08-04 | — | — | US | disclosed |
| US-4139342-A | POLYMETHYL METHACRYLATE, POLYSTYRENE, POLYESTERS, EPXOY RESINS, XANTHENE DYES, CARBON-BRIDGED DYES | HUGHES AIRCRAFT COMPANY (US) | 1979-02-13 | — | — | US | disclosed |
| US-4053430-A | OXALIC ACID ESTERS | AMERICAN CYANAMID COMPANY (US) | 1977-10-11 | — | — | US | disclosed |