Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 5/20 | 0.52 |
| ▸ | BCHE known ✓ | P06276 | 2/20 | 0.52 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.52 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.52 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.52 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.52 |
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.52 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.52 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.52 |
| ▸ | NOX1 | Q9Y5S8 | 10/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | SNCA | P37840 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27752615 | 1.00 | NOX1 (0.52) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL3416420 | 0.98 | NOX1 (0.53) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL4938759 | 0.97 | NOX1 (0.52) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL4931906 | 0.97 | NOX1 (0.52) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL28571616 | 0.84 | NOX1 (0.57) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL31207184 | 0.81 | NOX1 (0.48) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL6480585 | 0.81 | NOX1 (0.48) | NOX1MAPTGAAMEN1KMT2A | |
| Iodide SCHEMBL16344749 | 0.80 | NOX1 (0.47) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL1373026 | 0.80 | NOX1 (0.47) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL1373023 | 0.80 | NOX1 (0.47) | NOX1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242103-A | Methyl methacrylate-containing composition and method for producing methyl methacrylate polymer | 三菱化学株式会社 | 2023-12-15 | — | — | CN | disclosed |
| CN-117209450-A | Chemical synthesis method of diaminophenothiazinium compound including methyl sulfonium chloride (MTC) | 维斯塔实验室有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117203245-A | Methyl methacrylate-containing composition and method for producing methyl methacrylate polymer | 三菱化学株式会社 | 2023-12-08 | — | — | CN | disclosed |
| CN-117203249-A | Composition containing methyl methacrylate | 三菱化学株式会社 | 2023-12-08 | — | — | CN | disclosed |
| CN-110092764-B | Chemical synthesis method of diaminophenothiazinium compound including methyl sulfonium chloride (MTC) | 维斯塔实验室有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-116410155-A | Method for preparing 3, 7-bis (dimethylamino) phenothiazin-5-ium iodide | 普如制药生命解决方案公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-110382472-B | Method for preparing 3, 7-bis (dimethylamino) phenothiazin-5-ium iodide | 普如制药生命解决方案公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-116080089-A | Method for manufacturing automotive window glass structure and method for evaluating dry treatment | ＡＧＣ株式会社 | 2023-05-09 | — | — | CN | disclosed |
| CN-107848992-B | Method for chemically synthesizing substituted 10H-phenothiazine-3, 7-diamine compound | 维斯塔实验室有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-114555091-A | Formula product for preventing and/or treating peripheral neuropathy and related diseases thereof | 罗颍诗 | 2022-05-27 | — | — | CN | disclosed |
| CN-110249007-B | Synthesis of thiosulfonic acids by periodic acid-mediated oxidative coupling of thiosulfonic acids with anilines | 维斯塔实验室有限公司 | 2021-06-29 | — | — | CN | disclosed |
| US-5736595-A | HEAT TREATED MIXTURE COMPRISING CROSSLINKABLE POLYSACCHARIDE, ACRYLIC POLYMER, LOW MELTING MATRIX MATERIAL, CROSSLINKING AGENT, AND GEL ANTIBLOCKING AGENT; BIODEGRADABLE, HIGH STRENGTH | CHEMISCHE FABRIK STOCKHAUSEN GMBH (DE) | 1998-04-07 | — | — | US | disclosed |