Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 2-Mercaptoethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Mercaptoethanol SCHEMBL8849418 | 1.00 | — | — | |
| 2-Mercaptoethanol SCHEMBL8849476 | 1.00 | — | — | |
| 2-Mercaptoethanol SCHEMBL3423743 | 1.00 | — | — | |
| 2-Mercaptoethanol SCHEMBL11131405 | 0.95 | — | — | |
| 2-Mercaptoethanol SCHEMBL3727625 | 0.94 | — | — | |
| 2-Mercaptoethanol SCHEMBL5702 | 0.94 | — | — | |
| 2-Mercaptoethanol SCHEMBL9279180 | 0.89 | — | — | |
| 2-Mercaptoethanol SCHEMBL1308159 | 0.89 | — | — | |
| 2-Mercaptoethanol SCHEMBL10577105 | 0.89 | TSHR (0.40) | — | |
| 2-Mercaptoethanol SCHEMBL3139265 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298549-A | M protein assay and uses thereof | 百时美施贵宝公司 | 2022-11-04 | — | — | CN | claimed |
| EP-4055392-A1 | M-PROTEIN ASSAYS AND USES THEREOF | Bristol-Myers Squibb Company (US) | 2022-09-14 | — | — | EP | claimed |
| CN-106588722-B | The synthesis of thio ketal connection unit and its purposes in DNA sequencing | 上海交通大学 | 2018-08-03 | — | — | CN | claimed |
| EP-0501780-B1 | Liquid organotinthioalkanol stabilizer compositions, preparation and use thereof and vinyl halide resin compositions containing them | ATOCHEM NORTH AMERICA ELF (US) | 1997-06-25 | — | — | EP | claimed |
| EP-0419394-B1 | Non-digoxin-like Na+,K+-ATPase inhibitory factor | SANCHO ROF JOSE MARIA (ES) | 1994-12-14 | — | — | EP | claimed |
| CN-115298549-A | M protein assay and uses thereof | 百时美施贵宝公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-106083676-B | Thio ketal connection unit and its synthetic method, purposes | 上海交通大学 | 2019-01-11 | — | — | CN | disclosed |
| CN-106588722-B | The synthesis of thio ketal connection unit and its purposes in DNA sequencing | 上海交通大学 | 2018-08-03 | — | — | CN | disclosed |
| CN-1259170-A | Plant amino acid biosynthetic enzymes | DU PONT (US) | 2000-07-05 | — | — | CN | disclosed |
| EP-0501780-B1 | Liquid organotinthioalkanol stabilizer compositions, preparation and use thereof and vinyl halide resin compositions containing them | ATOCHEM NORTH AMERICA ELF (US) | 1997-06-25 | — | — | EP | disclosed |
| EP-0501780-A1 | Liquid organotinthioalkanol stabilizer compositions, preparation and use thereof and vinyl halide resin compositions containing them | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1992-09-02 | — | — | EP | disclosed |
| US-5109046-A | Liquid organotinthioalkanol stabilizer compositions and vinyl halide resin compositions containing the same | ATOCHEM NORTH AMERICA, INC. (US) | 1992-04-28 | — | — | US | disclosed |
| US-5102990-A | Incubating the protein containing monosulfide or disulfide bonds with a tin/II/ agent, purifying, adding a second tin/II/ agent and sulfur-containing complexes, adding radionucleotide | RHOMED INCORPORATED (US) | 1992-04-07 | — | — | US | disclosed |
| US-5063203-A | Anticoagulants, humans | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1991-11-05 | — | — | US | disclosed |