SCHEMBL9102436

SCHEMBL9102436

CCCNc1nc(NCCC)nc(NOCC(F)F)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
KMT2A Q03164 3/20 0.39
LMNA P02545 2/20 0.37
MEN1 O00255 1/20 0.37
NR1I2 O75469 1/20 0.36
AHR P35869 1/20 0.36
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA9 Q16790 3/20 0.35
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
PKM P14618 1/20 0.33
RAD52 P43351 1/20 0.33
CHRNA7 P36544 1/20 0.32
KCNH3 Q9ULD8 3/20 0.32
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
APP P05067 1/20 0.31
BCHE P06276 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL9106605 0.91 CA1 (0.39) CYP1A2CYP2C19KMT2ALMNAMEN1
Sulfuric Acid SCHEMBL9106610 0.87 CA1 (0.39) CYP1A2CYP2C19KMT2ALMNAMEN1
SCHEMBL10543159 0.74 CYP1A2 (0.61) CYP1A2CYP2C19KMT2ALMNAMEN1
SCHEMBL9102497 0.74 CYP1A2 (0.58) CYP1A2CYP2C19KMT2ALMNAMEN1
SCHEMBL9106747 0.73 CYP1A2 (0.49) CYP1A2CYP2C19KMT2ALMNAMEN1
SCHEMBL9104656 0.72 CYP1A2 (0.45) CYP1A2CYP2C19KMT2ALMNAMEN1
SCHEMBL17158227 0.72 CYP1A2 (0.45) CYP1A2CYP2C19KMT2ALMNAMEN1
Hydrochloric Acid SCHEMBL9108143 0.72 CYP1A2 (0.56) CYP1A2CYP2C19KMT2ALMNAMEN1
Hydrochloric Acid SCHEMBL9106903 0.71 CYP1A2 (0.44) CYP1A2CYP2C19KMT2ALMNAMEN1
Hydrochloric Acid SCHEMBL15720806 0.71 CYP1A2 (0.44) CYP1A2CYP2C19KMT2ALMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150374706-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. 2015-12-31 US claimed
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-11-22 US claimed
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-06-07 US claimed
US-20260137675-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS TO TREAT DRUG OVERDOSE ENALARE THERAPEUTICS INC (US) 2026-05-21 US disclosed
US-12544369-B2 Methods and pharmaceutical compositions to treat drug overdose ENALARE THERAPEUTICS INC. (US) 2026-02-10 US disclosed
US-20250325554-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS TO TREAT RESPIRATORY DEPRESSION IN PATIENTS ENALARE THERAPEUTICS INC (US) 2025-10-23 US disclosed
EP-4543455-A2 METHODS OF TREATING NEUROLOGICAL VENTILATORY INSUFFICIENCY Enalare Therapeutics Inc. (US) 2025-04-30 EP disclosed
WO-2025080559-A1 METHODS AND COMPOSITIONS FOR TREATING DRUG OVERDOSE ENALARE THERAPEUTICS INC. (US) 2025-04-17 WO disclosed
US-20250114370-A1 METHODS AND COMPOSITIONS FOR TREATING DRUG OVERDOSE ENALARE THERAPEUTICS INC (US) 2025-04-10 US disclosed
US-20250032496-A1 METHODS OF TREATING RESPIRATORY DEPRESSION MODULATED BY A NON-OPIOID AGENT ENALARE THERAPEUTICS INC (US) 2025-01-30 US disclosed
US-12138267-B2 Methods of treating respiratory depression modulated by a non-opioid agent ENALARE THERAPEUTICS INC. (US) 2024-11-12 US disclosed
US-20140371224-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. 2014-12-18 US disclosed
US-20140371224-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. 2014-12-18 US disclosed
US-20140371224-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES GALLEON PHARMACEUTICALS, INC. 2014-12-18 US disclosed
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-11-22 US disclosed
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-11-22 US disclosed
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-11-22 US disclosed
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-06-07 US disclosed
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-06-07 US disclosed
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases GALLEON PHARMACEUTICALS, INC. 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544369-B2 Methods and pharmaceutical compositions to treat drug overdose OPRK1, OPRD1, OPRM1 CYP1A2 138/4885CYP2C19 308/4885KMT2A 1148/4885
US-20120142647-A1 Novel Compounds as Respiratory Stimulants for Treatment of Breathing Control Disorders or Diseases MTNR1B, CHRM3, ADRA2C CYP1A2 457/4885CYP2C19 672/4885KMT2A 1945/4885
US-12138267-B2 Methods of treating respiratory depression modulated by a non-opioid agent OPRK1, OPRM1, OPRD1 CYP1A2 923/4885CYP2C19 1046/4885KMT2A 1896/4885
US-20260137675-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS TO TREAT DRUG OVERDOSE ADRA2B, ADRB1, ADRB2 CYP1A2 89/4885CYP2C19 93/4885KMT2A 2138/4885
US-20120295911-A1 Novel Compounds and Compositions for Treatment of Breathing Control Disorders or Diseases PER2, SMPD4, NDUFB5 CYP1A2 1058/4885CYP2C19 1600/4885KMT2A 3102/4885
US-20250325554-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS TO TREAT RESPIRATORY DEPRESSION IN PATIENTS NDUFB6, NDUFB7, CHRM5 CYP1A2 895/4885CYP2C19 801/4885KMT2A 2000/4885
US-20250032496-A1 METHODS OF TREATING RESPIRATORY DEPRESSION MODULATED BY A NON-OPIOID AGENT OPRK1, OPRM1, OPRD1 CYP1A2 923/4885CYP2C19 1046/4885KMT2A 1896/4885
US-20140371224-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES PER2, MTNR1B, NDUFB5 CYP1A2 2352/4885CYP2C19 3493/4885KMT2A 2815/4885
US-20250114370-A1 METHODS AND COMPOSITIONS FOR TREATING DRUG OVERDOSE ADRA2A, ADRA2C, OPRM1 CYP1A2 50/4885CYP2C19 288/4885KMT2A 1020/4885
US-20150374706-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF BREATHING CONTROL DISORDERS OR DISEASES PER2, SMPD4, NDUFB5 CYP1A2 1058/4885CYP2C19 1600/4885KMT2A 3102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.