Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR known ✓ | P00533 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 12/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22599 | 0.98 | KDM4A (0.40) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL7502000 | 0.98 | KDM4A (0.40) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| Ammonia Solution, Strong SCHEMBL9070327 | 0.96 | KDM4A (0.39) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| Bromide SCHEMBL1061717 | 0.96 | KDM4A (0.39) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| Bromomethane SCHEMBL3331850 | 0.94 | KDM4A (0.38) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL4242756 | 0.94 | KDM4A (0.38) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| Iodomethane SCHEMBL3333482 | 0.94 | KDM4A (0.38) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| Chloromethane SCHEMBL219838 | 0.94 | KDM4A (0.38) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL4859244 | 0.94 | KDM4A (0.46) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| Acetic Acid SCHEMBL6238301 | 0.94 | PAOX (0.39) | KDM4AKDM4CKDM5AKDM7APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115516030-A | Compositions and methods for increasing wet and dry strength | 凯米拉公司 | 2022-12-23 | — | — | CN | claimed |
| CN-115516031-A | GPAM compositions and methods | 凯米拉公司 | 2022-12-23 | — | — | CN | claimed |
| EP-1751113-A1 | UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | Bristol-Myers Squibb Pharma Company (US) | 2007-02-14 | — | — | EP | claimed |
| WO-2005113511-A1 | UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-12-01 | — | — | WO | claimed |
| US-6866378-B2 | Microwave or radiofrequency dryable thermal ink comprising water, colorant and conductive additive; high speed | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2005-03-15 | — | — | US | claimed |
| US-20040080593-A1 | Conductive additives for use in printing processes employing radiational drying | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2004-04-29 | — | — | US | claimed |
| EP-0695423-B1 | POLYMER CONTAINING CONTROL REAGENTS AND POLYMERS USEFUL IN CONTROL REAGENTS | ROCHE DIAGNOSTICS CORP (US) | 2001-11-28 | — | — | EP | claimed |
| EP-0702006-B1 | Weakly basic polymerizable monomers and polymers prepared therefrom | JOHNSON & JOHNSON CLIN DIAG (US) | 2000-05-10 | — | — | EP | claimed |
| EP-0717056-B1 | An aqueous dispersion of an amphoteric water-soluble polymer, a method of manufacturing the same, and a treating agent comprising the same | HYMO CORP (JP) | 1999-06-23 | — | — | EP | claimed |
| EP-0695423-A4 | POLYMER CONTAINING CONTROL REAGENTS AND POLYMERS USEFUL IN CONTROL REAGENTS | BOEHRINGER MANNHEIM CORP (US) | 1998-07-29 | — | — | EP | claimed |
| US-5708071-A | FLOCCULATION, SEWAGE TREATMENT | HYMO CORPORATION (JP) | 1998-01-13 | — | — | US | claimed |
| EP-0717056-A2 | An aqueous dispersion of an amphoteric water-soluble polymer, a method of manufacturing the same, and a treating agent comprising the same | HYMO CORPORATION (JP) | 1996-06-19 | — | — | EP | claimed |
| EP-0695423-A1 | POLYMER CONTAINING CONTROL REAGENTS AND POLYMERS USEFUL IN CONTROL REAGENTS | BOEHRINGER MANNHEIM CORPORATION (US) | 1996-02-07 | — | — | EP | claimed |
| WO-1994024551-A1 | POLYMER CONTAINING CONTROL REAGENTS AND POLYMERS USEFUL IN CONTROL REAGENTS | BOEHRINGER MANNHEIM CORPORATION (US) | 1994-10-27 | — | — | WO | claimed |
| EP-0284081-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1994-08-10 | — | — | EP | claimed |
| EP-0213317-B1 | BASE-CATALYZED, LOW TEMPERATURE SELF-CROSSLINKING POLYMERS | National Starch and Chemical Investment Holding Corporation (US) | 1991-12-04 | — | — | EP | claimed |
| US-11680184-B2 | Anti-stick processing aids and use thereof in the production of water-absorbing particles | EVONIK SUPERABSORBER GMBH (DE) | 2023-06-20 | — | — | US | disclosed |
| CN-115726215-A | Composition and method for making paper | 埃科莱布美国股份有限公司 | 2023-03-03 | — | — | CN | disclosed |
| US-4299898-A | Positively charged toners containing quaternary ammonium salts attached to acrylate polymers | XEROX CORPORATION (US) | 1981-11-10 | — | — | US | disclosed |
| US-4271058-A | Stable aqueous solutions of certain vinyl copolymers | ROHM GMBH (DE) | 1981-06-02 | — | — | US | disclosed |