Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.43 |
| ▸ | S1PR2 known ✓ | O95136 | 5/20 | 0.39 |
| ▸ | S1PR1 known ✓ | P21453 | 5/20 | 0.39 |
| ▸ | S1PR3 known ✓ | Q99500 | 5/20 | 0.39 |
| ▸ | S1PR4 known ✓ | O95977 | 4/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | FDPS | P14324 | 5/20 | 0.44 |
| ▸ | LAP3 | P28838 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1831242 | 1.00 | SPHK1 (0.45) | SPHK1FDPSOPRM1LAP3LMNA | |
| Hydrochloric Acid SCHEMBL28887929 | 1.00 | SPHK1 (0.45) | SPHK1FDPSOPRM1LAP3LMNA | |
| Hydrochloric Acid SCHEMBL2783892 | 1.00 | SPHK1 (0.45) | SPHK1FDPSOPRM1LAP3LMNA | |
| Hydrochloric Acid SCHEMBL15917465 | 1.00 | SPHK1 (0.45) | SPHK1FDPSOPRM1LAP3LMNA | |
| Hydrochloric Acid SCHEMBL28563644 | 1.00 | SPHK1 (0.45) | SPHK1FDPSOPRM1LAP3LMNA | |
| Bromide SCHEMBL15917631 | 0.98 | SPHK1 (0.44) | SPHK1FDPSOPRM1LAP3LMNA | |
| SCHEMBL17201413 | 0.98 | SPHK1 (0.47) | SPHK1FDPSOPRM1LAP3LMNA | |
| SCHEMBL10944415 | 0.98 | SPHK1 (0.47) | SPHK1FDPSOPRM1LAP3LMNA | |
| SCHEMBL238536 | 0.98 | SPHK1 (0.47) | SPHK1FDPSOPRM1LAP3LMNA | |
| SCHEMBL1838534 | 0.98 | SPHK1 (0.47) | SPHK1FDPSOPRM1LAP3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043864-A1 | MICROCAPSULE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国石油化工股份有限公司 | 2025-03-06 | — | — | WO | claimed |
| WO-2025043867-A1 | ASPHALT ADDITIVE, AND ASPHALT COMPOSITION AND PREPARATION METHOD THEREFOR | 中国石油化工股份有限公司 | 2025-03-06 | — | — | WO | claimed |
| CN-119552420-A | Asphalt additive, asphalt composition and preparation method thereof | 中国石油化工股份有限公司 | 2025-03-04 | — | — | CN | claimed |
| CN-119552518-A | Microcapsule and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-03-04 | — | — | CN | claimed |
| CN-116444993-B | Modified emulsified asphalt and preparation method thereof | 中国石油化工股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-116444993-A | Modified emulsified asphalt and preparation method thereof | 中国石油化工股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-101181185-B | Cosmetic emulsions manufactured at low temperature, with low viscosity and long-term stability, with coemulgators containing cationic groups | EVONIK GOLDSCHMIDT GMBH | 2012-08-29 | — | — | CN | claimed |
| WO-2025043864-A1 | MICROCAPSULE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国石油化工股份有限公司 | 2025-03-06 | — | — | WO | disclosed |
| WO-2025043867-A1 | ASPHALT ADDITIVE, AND ASPHALT COMPOSITION AND PREPARATION METHOD THEREFOR | 中国石油化工股份有限公司 | 2025-03-06 | — | — | WO | disclosed |
| CN-119552518-A | Microcapsule and preparation method and application thereof | 中国石油化工股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-119552420-A | Asphalt additive, asphalt composition and preparation method thereof | 中国石油化工股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-112226225-B | Temperature-resistant and salt-resistant surfactant composition for pressure reduction and injection increase of water injection well of low-permeability oil reservoir and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-112226225-A | Temperature-resistant and salt-resistant surfactant composition for pressure reduction and injection increase of water injection well of low-permeability oil reservoir and preparation method and application thereof | 中国石油化工股份有限公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-101181185-B | Cosmetic emulsions manufactured at low temperature, with low viscosity and long-term stability, with coemulgators containing cationic groups | EVONIK GOLDSCHMIDT GMBH | 2012-08-29 | — | — | CN | disclosed |
| CN-101181185-A | Cosmetic emulsions manufactured at low temperature, with low viscosity and long-term stability, with coemulgators containing cationic groups | EVONIK GOLDSCHMIDT GMBH (DE) | 2008-05-21 | — | — | CN | disclosed |
| US-5015769-A | Hair dyes formed by reaction of an alcohol with a phenol in the presence of a strong base for etherification followed by amination | L'OREAL (FR) | 1991-05-14 | — | — | US | disclosed |
| US-4666453-A | Nitro-meta-phenylenediamines halogenated in the 6th position and their use in dyeing keratinic substances | L'OREAL (FR) | 1987-05-19 | — | — | US | disclosed |