Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325255 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TGFBR1TET2CA14EGLN1 | |
| SCHEMBL10954682 | 0.77 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL10885891 | 0.77 | ALDH1A1 (0.46) | ALDH1A1USP2TSHR | |
| SCHEMBL988462 | 0.73 | ALDH1A1 (0.42) | ALDH1A1TET2 | |
| SCHEMBL990746 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TSHREGLN1 | |
| SCHEMBL988483 | 0.73 | DGAT1 (0.32) | CA2CA14 | |
| SCHEMBL28945233 | 0.72 | ALDH1A1 (0.39) | ALDH1A1USP2TSHRCA2TGFBR1 | |
| SCHEMBL10953877 | 0.70 | ALDH1A1 (0.62) | ALDH1A1TSHR | |
| SCHEMBL4896451 | 0.70 | ALDH1A1 (0.44) | ALDH1A1TSHRTGFBR1TET2CA14 | |
| SCHEMBL28453829 | 0.70 | ALDH1A1 (0.44) | ALDH1A1USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | claimed |
| US-20120156270-A1 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | L'OREAL (FR) | 2012-06-21 | — | — | US | disclosed |
| US-20120156270-A1 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | L'OREAL (FR) | 2012-06-21 | — | — | US | disclosed |
| EP-2451536-A2 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | L'Oréal (FR) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011003771-A2 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | L'OREAL (FR) | 2011-01-13 | — | — | WO | disclosed |
| US-20100172858-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE POLYMER OBTAINED FROM A DIELECTROPHILIC MONOMER | L'OREAL S.A. (FR) | 2010-07-08 | — | — | US | disclosed |
| US-20100172858-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE POLYMER OBTAINED FROM A DIELECTROPHILIC MONOMER | L'OREAL S.A. (FR) | 2010-07-08 | — | — | US | disclosed |
| EP-2124874-A2 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE POLYMER OBTAINED FROM A DIELECTROPHILIC MONOMER | L'Oreal (FR) | 2009-12-02 | — | — | EP | disclosed |
| US-7621966-B2 | Cosmetic composition comprising at least one pigment and/or at least one filler surface-treated beforehand with at least one organic agent and at least one electrophilic monomer | L'OREAL S.A. (FR) | 2009-11-24 | — | — | US | disclosed |
| US-7621966-B2 | Cosmetic composition comprising at least one pigment and/or at least one filler surface-treated beforehand with at least one organic agent and at least one electrophilic monomer | L'OREAL S.A. (FR) | 2009-11-24 | — | — | US | disclosed |
| US-20060110334-A1 | Two-compartment aerosol device comprising electrophilic monomers, and use thereof for the cosmetic treatment of the hair | L'OREAL S.A. (FR) | 2006-05-25 | — | — | US | disclosed |
| US-20060110350-A1 | Composition comprising electrophilic monomers and particular organic salts, and use thereof for cosmetic treatment of keratin materials | L'OREAL S.A. (FR) | 2006-05-25 | — | — | US | disclosed |
| US-20060088493-A1 | Composition and process for the cosmetic treatment of keratin materials based on electrophilic monomers and non-silicone polymers | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20060088488-A1 | Dyeing composition comprising a mixture of at least one pigment and at least one electrophilic monomer | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | L'OREAL S.A. (FR) | 2006-04-27 | — | — | US | disclosed |
| US-20060083706-A1 | Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| US-20060083762-A1 | Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| US-20060080792-A1 | Film-forming composition for the cosmetic treatment of keratin materials comprising at least one electrophilic monomer and at least one non-silicone polymer | L'OREAL S.A. (FR) | 2006-04-20 | — | — | US | disclosed |
| US-20060078523-A1 | Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair | L'OREAL S.A. (FR) | 2006-04-13 | — | — | US | disclosed |
| US-20060078522-A1 | Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt | L'OREAL S.A. (FR) | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060110334-A1 | Two-compartment aerosol device comprising electrophilic monomers, and use thereof for the cosmetic treatment of the hair | POLR1C, TRPA1, GSTM2 | ALDH1A1 492/4885USP2 786/4885TSHR 4318/4885 |
| US-20060088493-A1 | Composition and process for the cosmetic treatment of keratin materials based on electrophilic monomers and non-silicone polymers | KRT18, CUTA, MARK1 | ALDH1A1 3552/4885USP2 2854/4885TSHR 4581/4885 |
| US-20060083762-A1 | Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles | KRT18, PRKDC, ACP1 | ALDH1A1 828/4885USP2 1971/4885TSHR 4297/4885 |
| US-20100172858-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE POLYMER OBTAINED FROM A DIELECTROPHILIC MONOMER | KRT18, DSG1, DSC1 | ALDH1A1 320/4885USP2 4029/4885TSHR 4403/4885 |
| US-20060085922-A1 | Oxidizing composition comprising at least one electrophilic monomer and at least one non-benzoquinone oxidant | KRT18, GPX4, NOX4 | ALDH1A1 303/4885USP2 1996/4885TSHR 4243/4885 |
| US-20060083706-A1 | Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant | MITF, CUTA, NACA | ALDH1A1 43/4885USP2 1866/4885TSHR 3327/4885 |
| US-20060078523-A1 | Composition comprising at least one electrophilic monomer and at least one acid in a cosmetically acceptable anhydrous medium, and use thereof for cosmetic treatment of the hair | HOGA1, OAT, SUCLG1 | ALDH1A1 18/4885USP2 3505/4885TSHR 4459/4885 |
| US-20060088488-A1 | Dyeing composition comprising a mixture of at least one pigment and at least one electrophilic monomer | KRT18, IK, DDR1 | ALDH1A1 155/4885USP2 4315/4885TSHR 4653/4885 |
| US-20060110350-A1 | Composition comprising electrophilic monomers and particular organic salts, and use thereof for cosmetic treatment of keratin materials | KRT18, PRKDC, CUTA | ALDH1A1 992/4885USP2 4077/4885TSHR 4710/4885 |
| US-20060078522-A1 | Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt | KRT18, DSG1, DSC1 | ALDH1A1 1453/4885USP2 4051/4885TSHR 4360/4885 |
| US-20120156270-A1 | METHOD FOR SMOOTHING OUT THE SKIN BY FILLING IN RECESSED PORTIONS | EPAS1, PGF, PASK | ALDH1A1 4610/4885USP2 2168/4885TSHR 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.