Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.31 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.30 |
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64334 | 0.97 | — | — | |
| SCHEMBL29433272 | 0.97 | TSHR (0.35) | ALDH1A1L3MBTL1TSHRTDP1CA1 | |
| Ammonia Solution, Strong SCHEMBL2512351 | 0.94 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1TSHRTDP1CA1 | |
| SCHEMBL16563489 | 0.89 | — | — | |
| SCHEMBL782960 | 0.88 | ATR (0.32) | ALDH1A1L3MBTL1TSHRTDP1CA1 | |
| Ethylene Glycol SCHEMBL29059571 | 0.88 | ATR (0.32) | ALDH1A1L3MBTL1TSHRTDP1 | |
| Ethylene Glycol SCHEMBL1788495 | 0.88 | ATR (0.32) | ALDH1A1L3MBTL1TSHRTDP1 | |
| SCHEMBL16563491 | 0.86 | — | — | |
| SCHEMBL16564061 | 0.86 | — | — | |
| SCHEMBL575585 | 0.86 | CES1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101605591-A | Crosslinked cellulose membranes | GE HEALTHCARE BIO SCIENCES AB (SE) | 2009-12-16 | — | — | CN | claimed |
| EP-3885382-B1 | MONODISPERSE HYDROGEL PARTICLES | KURARAY CO (JP) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024237222-A1 | METHOD FOR PRODUCING CELLS | 株式会社クラレ | 2024-11-21 | — | — | WO | disclosed |
| WO-2024176915-A1 | DRY HYDROGEL-FORMING ARTICLE, HYDROGEL, AND METHOD FOR PRODUCING DRY HYDROGEL-FORMING ARTICLE | 株式会社クラレ | 2024-08-29 | — | — | WO | disclosed |
| US-12043706-B2 | Monodisperse hydrogel particles | KURARAY CO., LTD. (JP) | 2024-07-23 | — | — | US | disclosed |
| US-20220017703-A1 | MONODISPERSE HYDROGEL PARTICLES | KURARAY CO., LTD. (JP) | 2022-01-20 | — | — | US | disclosed |
| EP-3885382-A1 | MONODISPERSE HYDROGEL PARTICLES | Kuraray Co., Ltd. (JP) | 2021-09-29 | — | — | EP | disclosed |
| CN-110198941-A | Pyrrolopyridine N- oxidized derivatives and its preparation method and application | 江苏豪森药业集团有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-110041253-A | Pyridines N- oxidized derivatives and its preparation method and application | 上海翰森生物医药科技有限公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-109928897-A | Biguanide derivative and its application for preventing and treating infarct disease | 四川大学华西医院 | 2019-06-25 | — | — | CN | disclosed |
| CN-102784392-A | Methods and compositions for use in treatment of patients with autoantibody positive disease | HUMAN GENOME SCIENCES INC | 2012-11-21 | — | — | CN | disclosed |
| CN-102482283-A | Raf inhibitor compounds and methods of use thereof | ARRAY BIOPHARMA INC | 2012-05-30 | — | — | CN | disclosed |
| CN-102460176-A | Differential polypeptide detection method and application thereof | RONGXIU LI | 2012-05-16 | — | — | CN | disclosed |
| CN-102149712-A | Pyrazolo [3,4-b ] pyridine Raf inhibitors | ARRAY BIOPHARMA INC | 2011-08-10 | — | — | CN | disclosed |
| CN-102083442-A | Antioxidant inflammation modulators oleanolic acid derivatives with amino and other modifications at C-17 | REATA PHARMACEUTICALS INC | 2011-06-01 | — | — | CN | disclosed |
| CN-102015707-A | RAF inhibitor compounds and methods of use thereof | ARRAY BIOPHARMA INC | 2011-04-13 | — | — | CN | disclosed |
| CN-101848641-A | Sulfonanilide compounds is as the purposes of weed killer herbicide | BAYER CROPSCIENCE AG | 2010-09-29 | — | — | CN | disclosed |
| CN-101605591-A | Crosslinked cellulose membranes | GE HEALTHCARE BIO SCIENCES AB (SE) | 2009-12-16 | — | — | CN | disclosed |
| CN-1649887-A | Polymer coated substrates for immobilization of biomolecules and cells | BECKMAN COULTER INC (US) | 2005-08-03 | — | — | CN | disclosed |
| EP-0263934-A1 | Method for separation and purification of biopolymers by affinity chromatography | DIAGEN Institut für molekularbiologische Diagnostik GmbH (DE) | 1988-04-20 | — | — | EP | disclosed |