Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3608 | 0.96 | — | — | |
| Propane SCHEMBL5723751 | 0.92 | — | — | |
| SCHEMBL28166849 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL21596295 | 0.92 | — | — | |
| Fluoride SCHEMBL25337972 | 0.92 | — | — | |
| SCHEMBL23319722 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL11717158 | 0.92 | — | — | |
| SCHEMBL29921519 | 0.92 | — | — | |
| Methylamine SCHEMBL6865611 | 0.89 | — | — | |
| Methylene Chloride SCHEMBL26983527 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058591-B1 | EPIMERISATION OF TRANS CHRYSANTHEMIC ACIDS AND INTERMEDIATES OBTAINED THEREFROM | ROUSSEL-UCLAF (FR) | 1984-10-03 | — | — | EP | claimed |
| US-4447637-A | Epimerization of trans chrysanthemates | ROUSSEL UCLAF (FR) | 1984-05-08 | — | — | US | claimed |
| EP-0058591-A1 | Epimerisation of trans chrysanthemic acids and intermediates obtained therefrom | ROUSSEL-UCLAF (FR) | 1982-08-25 | — | — | EP | claimed |
| CN-118076610-A | Macrocyclic compounds with ENT1 inhibitory activity | ITEOS比利时公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-116590286-A | Three-dimensional nucleic acid nano material, preparation method thereof and application thereof in stem cell therapy | 中山大学附属第三医院 | 2023-08-15 | — | — | CN | disclosed |
| US-20200392562-A1 | POLYMERASE CHAIN REACTION COMPOSITION COMPRISING AMINES | THERMO FISHER SCIENTIFIC BALTICS UAB (LT) | 2020-12-17 | — | — | US | disclosed |
| EP-3728633-A1 | POLYMERASE CHAIN REACTION COMPOSITION COMPRISING AMINES | THERMO FISHER SCIENTIFIC BALTICS UAB (LT) | 2020-10-28 | — | — | EP | disclosed |
| CN-111556900-A | Polymerase chain reaction compositions comprising amines | 赛默飞世尔科技波罗的海封闭股份公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-1072644-C | 4-fluoroalkyl substituted phenacyl guanidine, its preparing method, application as medicine or diagnosis agent and medicine containing such compound | HOECHST AG (DE) | 2001-10-10 | — | — | CN | disclosed |
| CN-1065861-C | Phenyl substituted alkenocarboxylic guanidine, preparation method, application as medicine or diagnostic agent adn medicine containing it | HOECHST AG (DE) | 2001-05-16 | — | — | CN | disclosed |
| CN-1063437-C | Fluorophenyl sbstd. alkenylc arboxylic acid-guanidine its preparation method, applied as medicine and diagnosis agent and medicine containing the compound | HOECHST AG (DE) | 2001-03-21 | — | — | CN | disclosed |
| CN-1049888-C | Benzoylguanidine, process for preparing same, their use as medicine and medicine containing same | HOECHST AG (DE) | 2000-03-01 | — | — | CN | disclosed |
| CN-1174833-A | Phenyl substituted alkenocarboxylic guanidine, preparation method, application as medicine or diagnostic agent adn medicine containing it | HOECHST AG (DE) | 1998-03-04 | — | — | CN | disclosed |
| CN-1153773-A | substituted benzoyl guanidine its preparation, application as medicine or diagnostic reagent and medicine containing the said compound | HOECHST AG (DE) | 1997-07-09 | — | — | CN | disclosed |
| CN-1143076-A | 4-fluoroalkyl substituted phenacyl guanidine, its preparing method, application as medicine or diagnosis agent and medicine containing such compound | HOECHST AG (DE) | 1997-02-19 | — | — | CN | disclosed |
| CN-1138029-A | Fluorophenyl sbstd. alkenylc arboxylic acid-guanidine its preparation method, applied as medicine and diagnosis agent and medicine containing the compound | HOECHST AG (DE) | 1996-12-18 | — | — | CN | disclosed |
| CN-1050018-A | Benzoylguanidines, they the preparation method, they are as the application of medicament and the medicament that contains them | HOECHST AG (DE) | 1991-03-20 | — | — | CN | disclosed |
| EP-0058591-B1 | EPIMERISATION OF TRANS CHRYSANTHEMIC ACIDS AND INTERMEDIATES OBTAINED THEREFROM | ROUSSEL-UCLAF (FR) | 1984-10-03 | — | — | EP | disclosed |
| US-4447637-A | Epimerization of trans chrysanthemates | ROUSSEL UCLAF (FR) | 1984-05-08 | — | — | US | disclosed |