Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Benzethonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 known ✓ | P04626 | 2/20 | 0.98 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.98 |
| ▸ | CHRM4 known ✓ | P08173 | 2/20 | 0.98 |
| ▸ | CHRM5 known ✓ | P08912 | 2/20 | 0.98 |
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.98 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.98 |
| ▸ | ADRA2B known ✓ | P18089 | 2/20 | 0.98 |
| ▸ | ADRA2C known ✓ | P18825 | 2/20 | 0.98 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.98 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.98 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.98 |
| ▸ | HTR2A known ✓ | P28223 | 2/20 | 0.98 |
| ▸ | HTR2C known ✓ | P28335 | 2/20 | 0.98 |
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.98 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.98 |
| ▸ | KCNH2 known ✓ | Q12809 | 2/20 | 0.98 |
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.98 |
| ▸ | NR3C1 known ✓ | P04150 | 1/20 | 0.98 |
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.98 |
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzethonium SCHEMBL22711570 | 1.00 | SMN1; SMN2 (0.98) | SMN1; SMN2HIF1ALMNATSHRTDP1 | |
| Benzethonium SCHEMBL7271853 | 0.99 | SMN1; SMN2 (0.95) | SMN1; SMN2HIF1ALMNATSHRTDP1 | |
| Benzethonium SCHEMBL122985 | 0.99 | SMN1; SMN2 (1.00) | SMN1; SMN2HIF1ALMNATSHRTDP1 | |
| Benzethonium SCHEMBL976365 | 0.98 | SMN1; SMN2 (0.96) | SMN1; SMN2HIF1ALMNATSHRTDP1 | |
| Benzethonium SCHEMBL4418328 | 0.98 | SMN1; SMN2 (0.98) | SMN1; SMN2HIF1ALMNATSHRTDP1 | |
| Benzethonium SCHEMBL927612 | 0.98 | SMN1; SMN2 (0.98) | SMN1; SMN2HIF1ALMNATSHRTDP1 | |
| Benzethonium SCHEMBL1672928 | 0.98 | SMN1; SMN2 (0.98) | SMN1; SMN2HIF1ALMNATSHRTDP1 | |
| Benzethonium SCHEMBL5549294 | 0.98 | SMN1; SMN2 (0.98) | SMN1; SMN2HIF1ALMNATSHRTDP1 | |
| Benzethonium SCHEMBL27797280 | 0.98 | SMN1; SMN2 (1.00) | SMN1; SMN2HIF1ALMNATSHRTDP1 | |
| Benzethonium SCHEMBL1951703 | 0.98 | SMN1; SMN2 (0.98) | SMN1; SMN2HIF1ALMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007133220-A1 | WOOD PRESERVATIVE | JENEVEIN EARL (US) | 2007-11-22 | — | — | WO | claimed |
| US-20060189497-A1 | Wood preservative | JENEVEIN EARL | 2006-08-24 | — | — | US | claimed |
| US-7045492-B2 | Cleaning composition comprising cationic surfactants, chelant, and an alcohol solvent mixture | Jenevein, Earl (US) | 2006-05-16 | — | — | US | claimed |
| US-20040162230-A1 | Cleaning composition and a method of making thereof | JENEVEIN, EARL | 2004-08-19 | — | — | US | claimed |
| EP-4744113-A2 | ELECTRODES FOR ENERGY STORAGE DEVICES | Nanoramic, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025014921-A9 | ELECTRODES FOR ENERGY STORAGE DEVICES | FASTCAP SYSTEMS CORPORATION (US) | 2025-10-16 | — | — | WO | disclosed |
| EP-4599485-A1 | ELECTRODES FOR ENERGY STORAGE DEVICES | Nanoramic, Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| CN-116023323-B | Preparation method of avibactam intermediate | 浙江工业大学 | 2025-06-17 | — | — | CN | disclosed |
| US-20250192187-A1 | ENERGY STORAGE DEVICE | NANORAMIC, INC. | 2025-06-12 | — | — | US | disclosed |
| WO-2025101774-A1 | ELECTRODES FOR ENERGY STORAGE DEVICES | FASTCAP SYSTEMS CORPORATION (US) | 2025-05-15 | — | — | WO | disclosed |
| WO-2025014921-A2 | ELECTRODES FOR ENERGY STORAGE DEVICES | FASTCAP SYSTEMS CORPORATION (US) | 2025-01-16 | — | — | WO | disclosed |
| EP-4487356-A1 | ENERGY STORAGE DEVICE | Fastcap Systems Corporation (US) | 2025-01-08 | — | — | EP | disclosed |
| US-20050143467-A1 | Stimulation of cpt-1 as a means to reduce weight | THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE LICENSING AND TECHNOLOGY DEVELOPMENT (US) | 2005-06-30 | — | — | US | disclosed |
| US-20050106217-A1 | Stimulation of CPT-1 as a means to reduce weight | JOHNS HOPKINS UNIVERSITY LICENSING AND TECHNOLOGY DEVELOPMENT (US) | 2005-05-19 | — | — | US | disclosed |
| EP-1471906-A1 | STIMULATION OF CPT-1 AS A MEANS TO REDUCE WEIGHT | Johns Hopkins University School of Medicine (US) | 2004-11-03 | — | — | EP | disclosed |
| US-20040162230-A1 | Cleaning composition and a method of making thereof | JENEVEIN, EARL | 2004-08-19 | — | — | US | disclosed |
| US-20040162230-A1 | Cleaning composition and a method of making thereof | JENEVEIN, EARL | 2004-08-19 | — | — | US | disclosed |
| WO-2003066043-A1 | STIMULATION OF CPT-1 AS A MEANS TO REDUCE WEIGHT | JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2003-08-14 | — | — | WO | disclosed |
| US-RE30309-E | N-Alkyl-3-pyridinium-methanol fluorides and derivatives thereof | PIERRE FABRE S.A. (FR) | 1980-06-17 | — | — | US | disclosed |
| US-4098879-A | DENTIFRICES AND ANTICARIES AGENTS | PIERRE FABRE S.A. (FR) | 1978-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050106217-A1 | Stimulation of CPT-1 as a means to reduce weight | CPT1B, CPT1A, CPT2 | ERBB2 4521/4885CHRM2 2048/4885CHRM4 1914/4885 |
| US-20050143467-A1 | Stimulation of cpt-1 as a means to reduce weight | CPT1B, CPT1A, CPT2 | ERBB2 4521/4885CHRM2 2048/4885CHRM4 1914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.