Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 known ✓ | P11387 | 4/20 | 0.60 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | STAT1 | P42224 | 1/20 | 0.59 |
| ▸ | CYCS | P99999 | 3/20 | 0.58 |
| ▸ | TERT | O14746 | 4/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014524 | 0.98 | TOP1 (0.62) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL8014529 | 0.98 | TOP1 (0.62) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL31677406 | 0.98 | TOP1 (0.62) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL7157353 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL5572880 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL483549 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL599424 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL483748 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL1465442 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| Hydrochloric Acid SCHEMBL483503 | 0.96 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8057918-B2 | Organic light-emitting diodes and methods for assembly and enhanced charge injection | NORTHWESTERN UNIVERSITY (US) | 2011-11-15 | — | — | US | disclosed |
| US-8053094-B2 | Organic light-emitting diodes and methods for assembly and enhanced charge injection | NORTHWESTERN UNIVERSITY (US) | 2011-11-08 | — | — | US | disclosed |
| US-7969088-B2 | Method of using silicon molecular components for controlling charge migration and light emission of organic light-emitting diodes | NORTHWESTERN UNIVERSITY (US) | 2011-06-28 | — | — | US | disclosed |
| US-7750175-B2 | Organic light-emitting diodes and related hole transport compounds | NORTHWESTERN UNIVERSITY (US) | 2010-07-06 | — | — | US | disclosed |
| US-20090284145-A1 | Organic Light-Emitting Diodes and Methods for Assembly and Enhanced Charge Injection | NATIONAL SCIENCE FOUNDATION | 2009-11-19 | — | — | US | disclosed |
| US-20090284137-A1 | ORGANIC LIGHT-EMITTING DIODES AND METHODS FOR ASSEMBLY AND EMISSION CONTROL | NORTHWESTERN UNIVERSITY | 2009-11-19 | — | — | US | disclosed |
| US-20090224657-A1 | ORGANIC LIGHT-EMITTING DIODES AND METHODS FOR ASSEMBLY AND ENHANCED CHARGE INJECTION | MARKS TOBIN J | 2009-09-10 | — | — | US | disclosed |
| US-20070170844-A1 | Organic light-emitting diodes and methods for assembly and emission control | NORTHWESTERN UNIVERSITY | 2007-07-26 | — | — | US | disclosed |
| WO-2006023950-A2 | ORGANIC LIGHT-EMITTING DIODES AND RELATED HOLE TRANSPORT COMPOUNDS | NORTHWESTERN UNIVERSITY (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20050260443-A1 | Organic light - emitting diodes and methods for assembly and enhanced charge injection | MARKS TOBIN J | 2005-11-24 | — | — | US | disclosed |
| US-20050234256-A1 | Organic light-emitting diodes and related hole transport compounds | NATIONAL SCIENCE FOUNDATION | 2005-10-20 | — | — | US | disclosed |
| US-6939625-B2 | Organic light-emitting diodes and methods for assembly and enhanced charge injection | Nôrthwestern University (US) | 2005-09-06 | — | — | US | disclosed |
| US-20050158579-A1 | Organic light-emitting diodes and methods for assembly and enhanced charge injection | NATIONAL SCIENCE FOUNDATION | 2005-07-21 | — | — | US | disclosed |
| US-20040092195-A1 | Organic light-emitting diodes and methods for assembly and emission control | NATIONAL SCIENCE FOUNDATION | 2004-05-13 | — | — | US | disclosed |
| US-20030162053-A1 | Organic light - emitting diodes and methods for assembly and enhanced charge injection | NATIONAL SCIENCE FOUNDATION | 2003-08-28 | — | — | US | disclosed |
| US-6586763-B2 | Electroluminescent article comprising anode, plurality of molecular conductive layers coupled to one another and to anode with silicon-oxygen bonds, cathode, molecular charge control layer coupled with silicon-oxygen bonds | NORTHWESTERN UNIVERSITY | 2003-07-01 | — | — | US | disclosed |
| US-20020179898-A1 | ORGANIC LIGHT-EMITTING DIODES AND METHODS FOR ASSEMBLY AND EMISSION CONTROL | NATIONAL SCIENCE FOUNDATION | 2002-12-05 | — | — | US | disclosed |
| US-6399221-B1 | Organic light-emitting diodes and methods for assembly and emission control | NORTHWESTERN UNIVERSITY | 2002-06-04 | — | — | US | disclosed |
| US-6361885-B1 | ANODES AND CATHODES FOR ELECTROLUMINESCENT DEVICE | ORGANIC DISPLAY TECHNOLOGY | 2002-03-26 | — | — | US | disclosed |
| US-5834100-A | Organic light-emitting dioddes and methods for assembly and emission control | NORTHWESTERN UNIVERSITY (US) | 1998-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234256-A1 | Organic light-emitting diodes and related hole transport compounds | CLTB, SLCO4C1, ILK | TOP1 2727/4885STAT3 2470/4885STAT1 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.