Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.35 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 known ✓ | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403624 | 0.99 | HTR2A (0.39) | HTR2AMEN1KMT2ACSNK1ENAAA | |
| Hydrochloric Acid SCHEMBL28712260 | 0.83 | NAAA (0.43) | HTR2AMEN1KMT2ACSNK1ENAAA | |
| Hydrochloric Acid SCHEMBL11785349 | 0.74 | HTR2A (0.43) | HTR2AMEN1KMT2ACSNK1ENAAA | |
| Hydrochloric Acid SCHEMBL4799254 | 0.74 | HTR2A (0.43) | HTR2AMEN1KMT2ACSNK1ENAAA | |
| Hydrochloric Acid SCHEMBL28715893 | 0.74 | HTR2A (0.43) | HTR2AMEN1KMT2ACSNK1ENAAA | |
| Hydrochloric Acid SCHEMBL6122957 | 0.74 | HTR2A (0.43) | HTR2AMEN1KMT2ACSNK1ENAAA | |
| Hydrochloric Acid SCHEMBL1170862 | 0.74 | HTR2A (0.43) | HTR2AMEN1KMT2ACSNK1ENAAA | |
| Hydrochloric Acid SCHEMBL4800361 | 0.74 | HTR2A (0.43) | HTR2AMEN1KMT2ACSNK1ENAAA | |
| Hydrochloric Acid SCHEMBL4618491 | 0.74 | HTR2A (0.43) | HTR2AMEN1KMT2ACSNK1ENAAA | |
| Hydrochloric Acid SCHEMBL10582696 | 0.74 | HTR2A (0.43) | HTR2AMEN1KMT2ACSNK1ENAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119713-B1 | LIQUID ELECTROGRAPHIC DEVELOPERS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-10-07 | — | — | EP | claimed |
| US-4547449-A | IMPROVED REPLENISHABILITY | EASTMAN KODAK COMPANY (US) | 1985-10-15 | — | — | US | claimed |
| EP-0119713-A1 | Liquid electrographic developers | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-09-26 | — | — | EP | claimed |
| EP-2291422-B1 | PIGMENT DISPERSANTS WITH MODIFIED COPOLYMERS | BASF SE (DE) | 2015-10-21 | — | — | EP | disclosed |
| US-8664324-B2 | Pigment dispersants with modified copolymers | BASF SE (DE) | 2014-03-04 | — | — | US | disclosed |
| US-20110144260-A1 | PIGMENT DISPERSANTS WITH MODIFIED COPOLYMERS | BASF SE (DE) | 2011-06-16 | — | — | US | disclosed |
| EP-2291422-A1 | PIGMENT DISPERSANTS WITH MODIFIED COPOLYMERS | BASF SE (DE) | 2011-03-09 | — | — | EP | disclosed |
| WO-2009156277-A1 | PIGMENT DISPERSANTS WITH MODIFIED COPOLYMERS | BASF SE (DE) | 2009-12-30 | — | — | WO | disclosed |
| US-7056650-B2 | Thermally developable materials containing cationic overcoat polymer | EASTMAN KODAK COMPANY (US) | 2006-06-06 | — | — | US | disclosed |
| US-7049054-B2 | Thermally developable materials containing ionic polymer interlayer | EASTMAN KODAK COMPANY (US) | 2006-05-23 | — | — | US | disclosed |
| US-20060051712-A1 | THERMALLY DEVELOPABLE MATERIALS CONTAINING IONIC POLYMER INTERLAYER | EASTMAN KODAK COMPANY | 2006-03-09 | — | — | US | disclosed |
| EP-1067433-A1 | High-efficiency plasma treatment of paper | EASTMAN KODAK COMPANY (US) | 2001-01-10 | — | — | EP | disclosed |
| EP-1067432-A1 | High-efficiency plasma treatment of polyolefins | EASTMAN KODAK COMPANY (US) | 2001-01-10 | — | — | EP | disclosed |
| US-6100312-A | A CURABLE QUATERNARY AMMONIUM ADDITION COPOLYMER WITH A DISPERSED FINE-GRAIN PIGMENT; STORAGE STABILITY; COLOR FILTER USED IN A LIQUID CRYSTAL DISPLAY ELEMENT | FUJI PHOTO CO., LTD. (JP) | 2000-08-08 | — | — | US | disclosed |
| US-5998091-A | COPOLYMER OF A MONOFUNCTIONAL MACROMONOMER HAVING A PARTICULAR POLYMERIZABLE DOUBLE BOND-CONTAINING GROUP SITUATED AT ONLY ONE END OF THE MAIN CHAIN, A QUATERNARY AMMONIUM SALT AND AN AMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0119713-B1 | LIQUID ELECTROGRAPHIC DEVELOPERS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-10-07 | — | — | EP | disclosed |
| US-4547449-A | IMPROVED REPLENISHABILITY | EASTMAN KODAK COMPANY (US) | 1985-10-15 | — | — | US | disclosed |
| EP-0119713-A1 | Liquid electrographic developers | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4273849-A | HALOGENATED POLYMER, ACRYLIC COPOLYMER | EASTMAN KODAK COMPANY (US) | 1981-06-16 | — | — | US | disclosed |
| US-4229513-A | CHLORINATED POLYETHYLENE, AND COPOLYMER OF POLAR MONOMER AND SOLUBILIZING MONOMER | EASTMAN KODAK COMPANY (US) | 1980-10-21 | — | — | US | disclosed |