Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.72 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.72 |
| ▸ | HTT | P42858 | 4/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.62 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | BRD4 | O60885 | 4/20 | 0.59 |
| ▸ | METAP2 | P50579 | 1/20 | 0.59 |
| ▸ | METAP1 | P53582 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2525083 | 1.00 | KDM4E (0.72) | KDM4ELMNAL3MBTL1HTTNPC1 | |
| Hydrochloric Acid SCHEMBL31286548 | 1.00 | KDM4E (0.72) | KDM4ELMNAL3MBTL1HTTNPC1 | |
| SCHEMBL112193 | 0.98 | KDM4E (0.74) | KDM4ELMNAL3MBTL1HTTNPC1 | |
| SCHEMBL10156363 | 0.85 | KDM4E (0.70) | KDM4ELMNAL3MBTL1HTTNPC1 | |
| SCHEMBL29203716 | 0.84 | KDM4E (0.74) | KDM4ELMNAL3MBTL1HTTNPC1 | |
| SCHEMBL9177673 | 0.84 | KDM4E (0.79) | KDM4ELMNAL3MBTL1HTTNPC1 | |
| SCHEMBL31237495 | 0.84 | KDM4E (0.79) | KDM4ELMNAL3MBTL1HTTNPC1 | |
| SCHEMBL30159468 | 0.84 | KDM4E (1.00) | KDM4ELMNAL3MBTL1HTTNPC1 | |
| SCHEMBL1782934 | 0.84 | KDM4E (1.00) | KDM4ELMNAL3MBTL1HTTNPC1 | |
| SCHEMBL15155384 | 0.83 | KDM4E (0.68) | KDM4ELMNAL3MBTL1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120113681-A | Composite disinfectant containing chlorine dioxide and preparation process thereof | 山东兆冠药业有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-119605800-A | Oilfield water injection bactericide containing plant sterilization component and preparation method thereof | 郑州德融科技有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-118389912-B | Rare earth modified aluminum alloy and preparation method thereof | 北京钜嘉机械有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-118389912-A | Rare earth modified aluminum alloy and preparation method thereof | 北京钜嘉机械有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-116461169-B | Efficient heat-dissipating plate for automobile control room equipment cabinet and preparation method thereof | 江阴百士特控制显示设备有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-116461169-A | Efficient heat-dissipating plate for automobile control room equipment cabinet and preparation method thereof | 江阴百士特控制显示设备有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-113072687-B | Carbazole porous polymer containing 8-hydroxyquinoline group, and preparation method and application thereof | 东南大学 | 2022-12-13 | — | — | CN | claimed |
| CN-113072687-A | Carbazole porous polymer containing 8-hydroxyquinoline group, and preparation method and application thereof | 东南大学 | 2021-07-06 | — | — | CN | claimed |
| EP-3137079-A1 | INHIBITORS OF JMJD2C AS ANTICANCER AGENTS | The J. David Gladstone Institutes (US) | 2017-03-08 | — | — | EP | claimed |
| US-20170044107-A1 | Inhibitors of JMJD2C as Anticancer Agents | THE J. DAVID GLADSTONE INSTITUTES | 2017-02-16 | — | — | US | claimed |
| WO-2015167874-A1 | INHIBITORS OF JMJD2C AS ANTICANCER AGENTS | THE J. DAVID GLADSTONE INSTITUTES (US) | 2015-11-05 | — | — | WO | claimed |
| CN-104415765-A | Preparation method of Ru-Ni bimetallic based ordered mesoporous carbon catalyst | SUZHOU OST ADVANCED MATERIALS CO LTD | 2015-03-18 | — | — | CN | claimed |
| CN-101597315-B | Organic metal coordination compound gelator and luminous gel composed of same | UNIV BEIJING | 2011-05-11 | — | — | CN | claimed |
| CN-101597315-A | A kind of organometallic complex gel factor reaches by its luminous gel that constitutes | UNIV BEIJING (CN) | 2009-12-09 | — | — | CN | claimed |
| CN-1288151-C | Metal complex type luminous material containing electron injection group and its preparation method | UNIV SHANXI (CN) | 2006-12-06 | — | — | CN | claimed |
| CN-1263822-C | Luminous material of metal complex type containing hole transmission group and preparation process thereof | UNIV SHANXI (CN) | 2006-07-12 | — | — | CN | claimed |
| CN-1597682-A | Metal complex type luminous material containing electron injection group and its preparation method | UNIV SHANXI (CN) | 2005-03-23 | — | — | CN | claimed |
| CN-1597838-A | Luminous material of metal complex type containing hole transmission group and preparation process thereof | UNIV SHANXI (CN) | 2005-03-23 | — | — | CN | claimed |
| EP-4622962-A1 | SMALL MOLECULAR WEIGHT CHEMICAL COMPOUND TO ANTAGONIZE EPH-EPHRIN TETRAMERIZATION AND INHIBIT BIDIRECTIONAL SIGNALING | The Board of Regents of the University of Texas System (US) | 2025-10-01 | — | — | EP | disclosed |
| US-4317887-A | NUCLEOPHILIC-MODIFIED POLYACRYLAMIDE, POLYSTYRENE, AND DIVINYLBENZENE-STYRENE COPOLYMER; ION EXCHANGE RESINS; FIREPROOFING | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1982-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044107-A1 | Inhibitors of JMJD2C as Anticancer Agents | KDM2A, KDM1B, KDM5C | GAA 4162/4885HSP90AA1 1397/4885KDM4E 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.