Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL710942 | 1.00 | CTSD (0.33) | CTSD | |
| Hydrochloric Acid SCHEMBL27553871 | 1.00 | CTSD (0.33) | CTSD | |
| Methane SCHEMBL8847115 | 0.97 | CTSD (0.32) | CTSD | |
| SCHEMBL812577 | 0.97 | CTSD (0.35) | CTSD | |
| Fluoride SCHEMBL1131348 | 0.94 | CTSD (0.33) | CTSD | |
| Bromide SCHEMBL1539586 | 0.94 | CTSD (0.33) | CTSD | |
| Iodide SCHEMBL27948708 | 0.94 | CTSD (0.33) | CTSD | |
| Fluoride SCHEMBL27948615 | 0.94 | CTSD (0.33) | CTSD | |
| Methyl Alcohol SCHEMBL5277411 | 0.92 | CTSD (0.32) | CTSD | |
| Chloromethane SCHEMBL8161132 | 0.92 | CTSD (0.32) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587256-B | Catalyst system and polymerization process using the same | 埃克森美孚化学专利公司 | 2023-05-19 | — | — | CN | claimed |
| CN-111587257-B | Mixed catalyst system with four metallocenes on a single support | 埃克森美孚化学专利公司 | 2023-02-10 | — | — | CN | claimed |
| CN-111108130-B | Has the advantages ofcontaining-CH2-SiMe3Hybrid catalysts of partially unbridged hafnocenes | 埃克森美孚化学专利公司 | 2022-06-28 | — | — | CN | claimed |
| CN-110431160-B | Supported catalyst system and method of use | 埃克森美孚化学专利公司 | 2021-12-31 | — | — | CN | claimed |
| CN-111587257-A | Mixed catalyst system with four metallocenes on a single support | 埃克森美孚化学专利公司 | 2020-08-25 | — | — | CN | claimed |
| CN-111587256-A | Catalyst system and polymerization process using the same | 埃克森美孚化学专利公司 | 2020-08-25 | — | — | CN | claimed |
| CN-111108130-A | Has the advantages ofcontaining-CH2-SiMe3Hybrid catalysts of partially unbridged hafnocenes | 埃克森美孚化学专利公司 | 2020-05-05 | — | — | CN | claimed |
| US-20190127502-A1 | Mixed Catalyst Systems with Four Metallocenes on a Single Support | EXXONMOBIL CHEMICAL PATENTS INC. | 2019-05-02 | — | — | US | claimed |
| CN-104159929-A | Supported composite metallocene catalyst, method for preparing the same, and method for preparing polyolefin using the same | SK INNOVATION CO LTD | 2014-11-19 | — | — | CN | claimed |
| CN-102656198-B | Process for the preparation of a particulate bimodal polyethylene product | TOTAL PETROCHEMICALS RES FELUY | 2014-05-28 | — | — | CN | claimed |
| CN-101080424-A | Organochromium/metallocene combination catalyst for producing bimodal resins | CHEVRON PHILLIPS CHEMICAL CO (US) | 2007-11-28 | — | — | CN | claimed |
| CN-1993389-A | Acidic activator-supports and catalysts for olefin polymerization | CHEVRON PHILLIPS CHEMICAL CO (US) | 2007-07-04 | — | — | CN | claimed |
| CN-1365366-A | Improvements in or relating to polymers | BOREALIS TECH OY (FI) | 2002-08-21 | — | — | CN | claimed |
| CN-1053673-C | Load catalyst system, preparation and application in polymerization of alkene thereof | HOECHST AG (DE) | 2000-06-21 | — | — | CN | claimed |
| EP-0685495-B1 | Method for using a supported metallocene catalyst system | PHILLIPS PETROLEUM CO (US) | 1998-04-08 | — | — | EP | claimed |
| US-5627247-A | COMPOUNDS OF CYCLOPENTADIENE OR INDENE WITH FLUORENE AND GROUP IV METALS | PHILLIPS PETROLEUM COMPANY (US) | 1997-05-06 | — | — | US | claimed |
| US-5594078-A | BRIDGED FLUORENYL METALLOCENE CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-01-14 | — | — | US | claimed |
| US-5541272-A | INDENYL-CONTAINING POLYMERIZATION CATALYSTS | PHILLIPS PETROLEUM COMPANY (US) | 1996-07-30 | — | — | US | claimed |
| CN-1101051-A | Preparation of cycloolefincopolymer | HOECHST AG (DE) | 1995-04-05 | — | — | CN | claimed |
| CN-1096517-A | Load catalyst system, its preparation and the application in olefinic polymerization thereof | HOECHST AG (DE) | 1994-12-21 | — | — | CN | claimed |