SCHEMBL1576902

SCHEMBL1576902

CCCCCCCCOc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 5/20 0.67
MCL1 Q07820 1/20 0.64
TP53 P04637 1/20 0.60
TSHR P16473 1/20 0.60
KAT8 Q9H7Z6 2/20 0.60
PLA2G4B P0C869 1/20 0.59
PLA2G2A P14555 1/20 0.56
RARB P10826 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29623817 1.00 PTPN11 (0.67) PTPN11MCL1TP53TSHRKAT8
SCHEMBL11694352 1.00 PTPN11 (0.67) PTPN11MCL1TP53TSHRKAT8
SCHEMBL29623919 1.00 PTPN11 (0.67) PTPN11MCL1TP53TSHRKAT8
SCHEMBL4653931 1.00 PTPN11 (0.67) PTPN11MCL1TP53TSHRKAT8
SCHEMBL223621 1.00 PTPN11 (0.67) PTPN11MCL1TP53TSHRKAT8
SCHEMBL9285957 0.98 MCL1 (0.66) PTPN11MCL1TP53TSHRKAT8
SCHEMBL29623897 0.95 MCL1 (0.69) PTPN11MCL1TP53TSHRKAT8
SCHEMBL1576849 0.95 MCL1 (0.69) PTPN11MCL1TP53TSHRKAT8
SCHEMBL538445 0.89 MCL1 (0.61) PTPN11MCL1KAT8
SCHEMBL1376266 0.88 PTPN11 (0.63) PTPN11TP53TSHRPLA2G4BPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144729-A1 A CLEANSING COMPOSITION L'OREAL (FR) 2026-05-28 US claimed
EP-4611719-A1 A CLEANSING COMPOSITION L'OREAL (FR) 2025-09-10 EP claimed
CN-120076784-A Cleaning composition 莱雅公司 2025-05-30 CN claimed
WO-2024092386-A1 A CLEANSING COMPOSITION L'OREAL (FR) 2024-05-10 WO claimed
US-8974804-B2 Composition in the form of an oil-in-water emulsion and uses thereof L'OREAL (FR) 2015-03-10 US claimed
US-20120301414-A1 COMPOSITION IN THE FORM OF AN OIL-IN-WATER EMULSION AND USES THEREOF L'OREAL (FR) 2012-11-29 US claimed
EP-1415645-B1 Composition in the form of an oil-in-water emulsion and its cosmetic uses OREAL (FR) 2007-10-03 EP claimed
US-20040166128-A1 Composition in the form of an oil-in-water emulsion and uses thereof L'OREAL (FR) 2004-08-26 US claimed
US-4910021-A Oral administered coated capsule for colonic absorption R. P. SCHERER CORPORATION (US) 1990-03-20 US claimed
EP-0036534-B1 AN ORALLY ADMINISTRABLE DRUG FORM COMPRISING A BETA-LACTAM ANTIBIOTIC AND AN ADJUVANT INTERx RESEARCH CORPORATION (US) 1987-09-23 EP claimed
EP-0225189-A2 Targeted enteral delivery system R.P. SCHERER CORPORATION (US) 1987-06-10 EP claimed
EP-0031561-B1 A RECTALLY ADMINISTERED SUPPOSITORY COMPRISING A DRUG AND AN ADJUVANT MERCK & CO. INC. (US) 1985-04-10 EP claimed
US-4470980-A Method of increasing oral absorption of β-lactam antibiotics INTERX RESEARCH CORP. (US) 1984-09-11 US claimed
US-4464363-A HYDROXY ARYL- OR HYDROXY ARALKYL ACIDS OR SALTS MERCK & CO., INC. (US) 1984-08-07 US claimed
US-4406896-A ANTIBIOTICS, ACIDS, HYDROXY MERCK & CO., INC. (US) 1983-09-27 US claimed
EP-0036534-A1 An orally administrable drug form comprising a beta-lactam antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-30 EP claimed
EP-0036145-A1 An orally administered drug form comprising a polar bioactive agent and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-23 EP claimed
EP-0035770-A2 An orally administered drug form comprising a glycosidic antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-16 EP claimed
EP-0031561-A2 A rectally administered suppository comprising a drug and an adjuvant MERCK & CO. INC. (US) 1981-07-08 EP claimed
US-20260144729-A1 A CLEANSING COMPOSITION L'OREAL (FR) 2026-05-28 US disclosed
WO-2025263641-A1 COMPOSITION COMPRISING GLYCOLIPID, CATIONIC POLYMER AND (POLY)HYDROXY ACID L'OREAL (FR) 2025-12-26 WO disclosed
EP-4611719-A1 A CLEANSING COMPOSITION L'OREAL (FR) 2025-09-10 EP disclosed
CN-120076784-A Cleaning composition 莱雅公司 2025-05-30 CN disclosed
US-20240269050-A1 ELECTROPORATION PROCESS FOR DELIVERING A COMPOSITION COMPRISING AT LEAST ONE HYDROXY ACID COMPOUND L'OREAL (FR) 2024-08-15 US disclosed
WO-2024092386-A1 A CLEANSING COMPOSITION L'OREAL (FR) 2024-05-10 WO disclosed
US-20240115469-A1 COMPOSITION FOR KERATIN FIBERS L'OREAL (FR) 2024-04-11 US disclosed
EP-4271356-A1 COMPOSITION FOR KERATIN FIBERS L'OREAL (FR) 2023-11-08 EP disclosed
CN-116600780-A Composition for keratin fibres 莱雅公司 2023-08-15 CN disclosed
WO-2022248669-A1 ELECTROPORATION PROCESS FOR DELIVERING A COMPOSITION COMPRISING AT LEAST ONE HYDROXY ACID COMPOUND L'OREAL (FR) 2022-12-01 WO disclosed
WO-2022118982-A1 PROCESS FOR TREATING KERATIN FIBERS L'OREAL (FR) 2022-06-09 WO disclosed
WO-2022118980-A1 COMPOSITION FOR KERATIN FIBERS L'OREAL (FR) 2022-06-09 WO disclosed
WO-2022118978-A1 COMPOSITION FOR KERATIN FIBERS L'OREAL (FR) 2022-06-09 WO disclosed
US-10481163-B1 Mass spectrometry method using mixed matrix SHIMADZU CORPORATION (JP) 2019-11-19 US disclosed
US-10481163-B1 Mass spectrometry method using mixed matrix SHIMADZU CORPORATION (JP) 2019-11-19 US disclosed
EP-2683351-B1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME OREAL (FR) 2019-10-16 EP disclosed
US-20160067160-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME OREAL (FR) 2016-03-10 US disclosed
US-8974804-B2 Composition in the form of an oil-in-water emulsion and uses thereof L'OREAL (FR) 2015-03-10 US disclosed
CN-102655839-B A cosmetic or dermatological composition with low stickiness, containing a lipophilic active ingredient OREAL 2014-11-12 CN disclosed
US-8716311-B2 Use of piperidine ester derivative as solvent in cosmetic compositions; cosmetic compositions comprising it L'OREAL (FR) 2014-05-06 US disclosed
US-20140056832-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME L'OREAL (FR) 2014-02-27 US disclosed
EP-2683351-A2 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME L'Oréal (FR) 2014-01-15 EP disclosed
US-20130196957-A1 ROLL-ON WITH HIGH SALICYLIC ACID CONTENT L'OREAL (FR) 2013-08-01 US disclosed
EP-2568293-A8 Matrix additive for mass spectrometry Shimadzu Corporation (JP) 2013-05-08 EP disclosed
US-20130062570-A1 MATRIX ADDITIVE FOR MASS SPECTROMETRY SHIMADZU CORPORATION (JP) 2013-03-14 US disclosed
EP-2568293-A1 Matrix additive for mass spectrometry Shimadzu Corporation (JP) 2013-03-13 EP disclosed
US-20120301414-A1 COMPOSITION IN THE FORM OF AN OIL-IN-WATER EMULSION AND USES THEREOF L'OREAL (FR) 2012-11-29 US disclosed
US-20120282197-A1 USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT L'OREAL (FR) 2012-11-08 US disclosed
US-20120269746-A1 USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT L'OREAL (FR) 2012-10-25 US disclosed
EP-2501359-A1 A COSMETIC OR DERMATOLOGICAL COMPOSITION WITH LOW STICKINESS, CONTAINING A LIPOPHILIC ACTIVE INGREDIENT L'Oréal (FR) 2012-09-26 EP disclosed
WO-2012119861-A2 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME L'OREAL (FR) 2012-09-13 WO disclosed
US-8263666-B2 Topical applying; mixture containing hydrophilic polysiloxane polymer and lipophilic compound amino acid and salicylic acid L'OREAL (FR) 2012-09-11 US disclosed
CN-102655839-A A cosmetic or dermatological composition with low stickiness, containing a lipophilic active ingredient OREAL 2012-09-05 CN disclosed
EP-2482791-A1 USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT L'Oréal (FR) 2012-08-08 EP disclosed
EP-2482793-A1 USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT L'Oréal (FR) 2012-08-08 EP disclosed
WO-2012093103-A2 TWO-PART COSMETIC PRODUCT L'OREAL (FR) 2012-07-12 WO disclosed
WO-2011061864-A1 A COSMETIC OR DERMATOLOGICAL COMPOSITION WITH LOW STICKINESS, CONTAINING A LIPOPHILIC ACTIVE INGREDIENT L'OREAL (FR) 2011-05-26 WO disclosed
WO-2011038776-A1 USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT L'OREAL (FR) 2011-04-07 WO disclosed
WO-2011038778-A1 USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT L'OREAL (FR) 2011-04-07 WO disclosed
WO-2010148101-A2 TOPICAL COMPOSITIONS CONTAINING A POLYMER FOR RELEASING AT LEAST ONE SALICYLIC ACID COMPOUND L'OREAL S.A. (FR) 2010-12-23 WO disclosed
WO-2010148104-A2 TOPICAL COMPOSITIONS CONTAINING A POLYMER FOR RELEASING AT LEAST ONE SALICYLIC ACID COMPOUND L'OREAL S.A. (FR) 2010-12-23 WO disclosed
US-20100256100-A1 ROLL-ON WITH HIGH SALICYLIC ACID CONTENT L'OREAL (FR) 2010-10-07 US disclosed
CN-101744739-A Use of an ester derived from 4-carboxy-2-pyrrolidinone as a solvent in cosmetic compositions and cosmetic compositions containing the ester OREAL 2010-06-23 CN disclosed
US-20100143276-A1 Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions L'OREAL (FR) 2010-06-10 US disclosed
US-20090285868-A1 Photostable cosmetic compositions comprising dibenzoylmethane/pyrrolidinone compounds L'OREAL (FR) 2009-11-19 US disclosed
US-20090029928-A1 PEELING PROCESS AND COMPOSITION L'OREAL (FR) 2009-01-29 US disclosed
WO-2008064979-A2 COSMETIC COMPOSITIONS CONTAINING A SILOXANE- CONTAINING ARYLALKYL BENZOATE AMIDE DERIVATIVE; USE OF SAID DERIVATIVE AS SOLVENT IN OILS; NOVEL SILOXANE- CONTAINING ARYLALKYL BENZOATE AMIDE DERIVATIVES L'OREAL (FR) 2008-06-05 WO disclosed
US-20070276044-A1 Peeling Cosmetic Method Using a 8-Hexadecene-1,16-Dicarboxylic Acid L'OREAL (FR) 2007-11-29 US disclosed
US-20040166128-A1 Composition in the form of an oil-in-water emulsion and uses thereof L'OREAL (FR) 2004-08-26 US disclosed
US-5667789-A EMULSIFIER FREE, COSMETIC AND DERMATOLOGICAL COMPOSITIONS, TREATMENT OF ACNE, AGING L'OREAL (FR) 1997-09-16 US disclosed
EP-0338808-B1 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INT INC (US) 1995-08-23 EP disclosed
EP-0225189-B1 TARGETED ENTERAL DELIVERY SYSTEM R.P. SCHERER CORPORATION (US) 1992-10-07 EP disclosed
US-5075416-A Suspending methanesulfonic acid and aromatic acid in aliphatic solvent, slowly adding unsaturated aromatic hydrocarbon RUTGERSWERKE AG (DE) 1991-12-24 US disclosed
US-5017546-A Metallized phenolic resins SCHENECTADY INTERNATIONAL, INC. 1991-05-21 US disclosed
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed
US-4910021-A Oral administered coated capsule for colonic absorption R. P. SCHERER CORPORATION (US) 1990-03-20 US disclosed
EP-0338808-A2 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INTERNATIONAL, INC. (US) 1989-10-25 EP disclosed
EP-0225189-A2 Targeted enteral delivery system R.P. SCHERER CORPORATION (US) 1987-06-10 EP disclosed
US-4355070-A COLOR FORMER, DEVELOPER, HEAT FUSIBLE MATERIAL AND OIL ABSORPTIVE PIGMENT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1982-10-19 US disclosed
US-4311758-A INORGANIC PIGMENTS IN THE COLOR DEVELOPER LAYER KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1982-01-19 US disclosed
US-4236732-A COLOR DEVELOPING LAYER CONTAINING PARTICLES OF A CHROMOGENIC MATERIAL, AN ACCEPTOR AND A HEAT FUSIBLE MATERIAL KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1980-12-02 US disclosed
US-4228222-A COLOR DEVELOPING LAYER INCLUDING WATER SOLUBLE RESIN AS BINDER KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1980-10-14 US disclosed
US-4168845-A Heat-sensitive record material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-09-25 US disclosed
US-4134847-A HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-01-16 US disclosed
US-4046941-A PRESSURE SENSITIVE COPYING SANKO CHEMICAL COMPANY LTD. (JA) 1977-09-06 US disclosed
US-3983292-A Pressure sensitive recording papers SANKO CHEMICAL COMPANY LTD. (JA) 1976-09-28 US disclosed
US-3983292-A Pressure sensitive recording papers SANKO CHEMICAL COMPANY LTD. (JA) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256100-A1 ROLL-ON WITH HIGH SALICYLIC ACID CONTENT SUCLG1, CUTA, SYVN1 PTPN11 2923/4885MCL1 4416/4885TP53 1507/4885
US-20070276044-A1 Peeling Cosmetic Method Using a 8-Hexadecene-1,16-Dicarboxylic Acid CUTA, RARA, RARG PTPN11 1508/4885MCL1 4148/4885TP53 1333/4885
US-20090029928-A1 PEELING PROCESS AND COMPOSITION CUTA, PRKCH, EBP PTPN11 1574/4885MCL1 4048/4885TP53 2799/4885
US-20090285868-A1 Photostable cosmetic compositions comprising dibenzoylmethane/pyrrolidinone compounds NOTUM, CYP51A1, DHPS PTPN11 1579/4885MCL1 2908/4885TP53 142/4885
US-20120301414-A1 COMPOSITION IN THE FORM OF AN OIL-IN-WATER EMULSION AND USES THEREOF PLOD3, CUTA, LOXL1 PTPN11 3469/4885MCL1 2887/4885TP53 1565/4885
US-20140056832-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME DIMT1, MAT2A, SCD PTPN11 4306/4885MCL1 3944/4885TP53 1744/4885
US-20040166128-A1 Composition in the form of an oil-in-water emulsion and uses thereof PLOD3, CUTA, LOXL1 PTPN11 3469/4885MCL1 2887/4885TP53 1565/4885
US-20240269050-A1 ELECTROPORATION PROCESS FOR DELIVERING A COMPOSITION COMPRISING AT LEAST ONE HYDROXY ACID COMPOUND KRT18, CD44, EPCAM PTPN11 4416/4885MCL1 3300/4885TP53 833/4885
US-20120282197-A1 USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT PLD1, PLD2, FFAR1 PTPN11 4853/4885MCL1 3444/4885TP53 1319/4885
US-20260144729-A1 A CLEANSING COMPOSITION SMURF1, CUTA, S100B PTPN11 3869/4885MCL1 4475/4885TP53 2338/4885
US-20130196957-A1 ROLL-ON WITH HIGH SALICYLIC ACID CONTENT SUCLG1, CUTA, SYVN1 PTPN11 2923/4885MCL1 4416/4885TP53 1507/4885
US-20160067160-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME DIMT1, FADS2, SCD PTPN11 4335/4885MCL1 3946/4885TP53 1681/4885
US-20120269746-A1 USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT DEGS1, CAPN1, PPT1 PTPN11 4563/4885MCL1 1860/4885TP53 507/4885
US-20100143276-A1 Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions FASN, ALOX12, PAH PTPN11 4533/4885MCL1 4092/4885TP53 935/4885
US-20240115469-A1 COMPOSITION FOR KERATIN FIBERS KRT18, COL14A1, KIF5C PTPN11 4647/4885MCL1 4723/4885TP53 2177/4885
US-20130062570-A1 MATRIX ADDITIVE FOR MASS SPECTROMETRY ASPH, P4HA1, DNPEP PTPN11 2207/4885MCL1 4709/4885TP53 3850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.