Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 5/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TET3 | O43151 | 1/20 | 0.30 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995392 | 0.98 | TET2 (0.38) | TET2ALOX15HSD17B10TET3TET1 | |
| Bromide SCHEMBL8931105 | 0.96 | TET2 (0.36) | TET2ALOX15HSD17B10TET3TET1 | |
| Sulfuric Acid SCHEMBL9103493 | 0.90 | TET2 (0.33) | TET2ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL4387248 | 0.88 | TET2 (0.34) | TET2ALOX15HSD17B10 | |
| SCHEMBL4654955 | 0.86 | TET2 (0.35) | TET2ALOX15HSD17B10 | |
| SCHEMBL1770041 | 0.84 | TET2 (0.30) | TET2 | |
| SCHEMBL7856854 | 0.83 | LMNA (0.40) | ALOX15 | |
| Hydrochloric Acid SCHEMBL7764314 | 0.80 | TET2 (0.34) | TET2ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL2710766 | 0.78 | TET2 (0.48) | TET2ALOX15HSD17B10TET3TET1 | |
| SCHEMBL1006556 | 0.78 | TET2 (0.35) | TET2ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1047 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060309-B1 | RINSE-OFF VOLUMIZING HAIR COMPOSITIONS CONTAINING STYLING POLYMERS AND POLYCATIONIC POLYMERS | KAO USA INC (US) | 2023-07-26 | — | — | EP | claimed |
| WO-2020036284-A1 | SUSTAINED-RELEASE FORMULATION OF CILOSTAZOL | 한국유나이티드제약 주식회사 | 2020-02-20 | — | — | WO | claimed |
| WO-2019063478-A1 | SUBMICRON PARTICLE FORMULATIONS | CAPSUGEL BELGIUM NV (BE) | 2019-04-04 | — | — | WO | claimed |
| EP-2956521-B1 | METHODS OF USING WELLBORE SERVICING COMPOSITIONS | HALLIBURTON ENERGY SERVICES INC (US) | 2017-10-18 | — | — | EP | claimed |
| EP-2956521-A1 | WELLBORE SERVICING COMPOSITIONS AND METHODS OF MAKING AND USING SAME | Halliburton Energy Services, Inc. (US) | 2015-12-23 | — | — | EP | claimed |
| WO-2014179121-A1 | WELLBORE SERVICING COMPOSITIONS AND METHODS OF MAKING AND USING SAME | HALLIBURTON ENERGY SERVICES, INC. (US) | 2014-11-06 | — | — | WO | claimed |
| US-20140318785-A1 | Wellbore Servicing Compositions and Methods of Making and Using Same | HALLIBURTON ENERGY SERVICES, INC. (US) | 2014-10-30 | — | — | US | claimed |
| US-8668010-B2 | Wellbore servicing compositions comprising a fluid loss agent and methods of making and using same | HALLIBURTON ENERGY SERVICES, INC. (US) | 2014-03-11 | — | — | US | claimed |
| EP-2649022-A1 | WELLBORE SERVICING COMPOSITIONS COMPRISING A FLUID LOSS AGENT AND METHODS OF MAKING AND USING SAME | Halliburton Energy Services, Inc. (US) | 2013-10-16 | — | — | EP | claimed |
| US-20130177485-A1 | DIAGNOSTIC DEVICE FOR IDENTIFYING RUPTURE OF MEMBRANE DURING PREGNANCY | MOMTEC LIFE LTD OF YAZMOT HAEMEK (IL) | 2013-07-11 | — | — | US | claimed |
| US-7923117-B2 | first monomer of the polymer includes at least one amine functional group; aminoethylmethacrylate; aminoethylacrylate; second monomer includes a carbon backbone having at least one silane functional group pendant; prevent dye from migrating | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2011-04-12 | — | — | US | claimed |
| US-20110065139-A1 | DIAGNOSTIC DEVICE FOR IDENTIFYING RUPTURE OF MEMBRANE DURING PREGNANCY | MULLERAD JACOB | 2011-03-17 | — | — | US | claimed |
| EP-1909741-B1 | denture support composition | RECKITT BENCKISER UK LTD (GB) | 2010-11-10 | — | — | EP | claimed |
| WO-2010079100-A1 | IMPROVEMENTS RELATING TO FABRIC CONDITIONERS | UNILEVER PLC (GB) | 2010-07-15 | — | — | WO | claimed |
| EP-2198299-A2 | A DIAGNOSTIC DEVICE FOR IDENTIFYING RUPTURE OF MEMBRANE DURING PREGNANCY | Mullerad, Jacob (IL) | 2010-06-23 | — | — | EP | claimed |
| WO-2009050711-A2 | A DIAGNOSTIC DEVICE FOR IDENTIFYING RUPTURE OF MEMBRANE DURING PREGNANCY | MULLERAD JACOB (IL) | 2009-04-23 | — | — | WO | claimed |
| US-20080249506-A1 | Methods of treating diverticula | STRYKER DEVELOPMENT LLC | 2008-10-09 | — | — | US | claimed |
| EP-1345594-B1 | THERMOFORMABLE SOLID PHARMACEUTICAL COMPOSITION FOR CONTROLLED RELEASE OF IVABRADINE | SERVIER LAB (FR) | 2007-01-24 | — | — | EP | claimed |
| EP-0923611-B1 | POLYACRYLAMIDE POLYMERISATION | ICI PLC (GB) | 2004-01-28 | — | — | EP | claimed |
| EP-0580529-B1 | Process for making paper or cardboard having improved retention | S N F (FR) | 1996-04-17 | — | — | EP | claimed |