Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Boric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | TSHR | P16473 | 1/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL7631361 | 1.00 | — | — | |
| Boric Acid SCHEMBL5145958 | 1.00 | LMNA (0.80) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL28246506 | 1.00 | LMNA (0.80) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL29683415 | 1.00 | — | — | |
| Boric Acid SCHEMBL1685958 | 1.00 | LMNA (0.80) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL27323803 | 1.00 | LMNA (0.80) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL29085738 | 1.00 | LMNA (0.80) | LMNATSHRTDP1 | |
| Boric Acid SCHEMBL458469 | 1.00 | — | — | |
| Boric Acid SCHEMBL16223734 | 0.91 | — | — | |
| Boric Acid SCHEMBL1435247 | 0.91 | LMNA (0.67) | LMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124865-A1 | PROCESS FOR POLYMERIZING CATIONICALLY POLYMERIZABLE OLEFIN | Bayer Inc. (CA) | 2001-08-22 | — | — | EP | claimed |
| US-5483014-A | Catalysts, method of preparing these catalysts, and polymerization processes wherein these catalysts are used | TURNER HOWARD W (US) | 1996-01-09 | — | — | US | claimed |
| EP-1572752-B1 | POLYMERIZATION PROCESSES | EXXONMOBIL CHEM PATENTS INC (US) | 2014-08-13 | — | — | EP | disclosed |
| EP-1578806-B1 | POLYMERIZATION PROCESSES | EXXONMOBIL CHEM PATENTS INC (US) | 2013-05-22 | — | — | EP | disclosed |
| EP-1572753-B1 | POLYMERIZATION PROCESSES | EXXONMOBIL CHEM PATENTS INC (US) | 2012-06-13 | — | — | EP | disclosed |
| EP-1578822-B1 | POLYMERS SUBSTANTIALLY FREE OF LONG CHAIN BRANCHING | EXXONMOBIL CHEM PATENTS INC (US) | 2011-04-06 | — | — | EP | disclosed |
| EP-1572751-B1 | POLYMERIZATION PROCESSES | EXXONMOBIL CHEM PATENTS INC (US) | 2010-06-23 | — | — | EP | disclosed |
| EP-1572766-B1 | POLYMERS WITH NEW SEQUENCE DISTRIBUTIONS | EXXONMOBIL CHEM PATENTS INC (US) | 2010-06-02 | — | — | EP | disclosed |
| EP-1572763-B1 | POLYMERS WITH NEW SEQUENCE DISTRIBUTIONS | EXXONMOBIL CHEM PATENTS INC (US) | 2010-05-26 | — | — | EP | disclosed |
| US-7723447-B2 | slurry polymerization in presence a cationic catalyst system, an environmentally friendly hydrofluorocarbon diluent, of one or more monomer(s) to form a single phase polymerization medium; prevent agglomeration and reactor fouling; utilizing boiling pool reactor systems | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-05-25 | — | — | US | disclosed |
| US-7582715-B2 | Polymers substantially free of long chain branching | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-09-01 | — | — | US | disclosed |
| WO-2002010227-A1 | METHOD FOR PRODUCING HIGHLY PRODUCTIVE SUPPORTED IONIC CATALYST FOR GAS PHASE POLYMERIZATION | UNIVATION TECHNOLOGIES, LLC (US) | 2002-02-07 | — | — | WO | disclosed |
| US-20020010083-A1 | Cationic catalysts and process for using said catalysts | EXXONMOBIL CHEMICAL PATENTS, INC. | 2002-01-24 | — | — | US | disclosed |
| EP-1152016-A1 | ETHYLENE COPOLYMER RUBBER, PROCESS FOR PRODUCING THE SAME, AND USE | Mitsui Chemicals, Inc. (JP) | 2001-11-07 | — | — | EP | disclosed |
| US-6291389-B1 | COMPRISING A CATION AND A COMPATIBLE NON-CORDINATING ANION; MONOMER, TEMPERATURE AND/OR SOLVENT DETERMINING WHETHER COORDINATION OR CATIONIC MECHANISM OR BOTH; COMPLEXES OF METALLOCENES AND LEWIS ACIDS; HIGH MOLECULAR WEIGHT | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-09-18 | — | — | US | disclosed |
| EP-1124865-A1 | PROCESS FOR POLYMERIZING CATIONICALLY POLYMERIZABLE OLEFIN | Bayer Inc. (CA) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000004061-A1 | PROCESS FOR POLYMERIZING CATIONICALLY POLYMERIZABLE OLEFIN | BAYER INC. (CA) | 2000-01-27 | — | — | WO | disclosed |
| US-6008307-A | Process for producing olefin polymers using cationic catalysts | EXXON CHEMICAL PATENTS INC (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0757698-A1 | CATIONIC CATALYSTS AND PROCESS FOR USING SAID CATALYSTS | EXXON CHEMICAL PATENTS INC. (US) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029940-A1 | CATIONIC CATALYSTS AND PROCESS FOR USING SAID CATALYSTS | EXXON CHEMICAL PATENTS INC. (US) | 1995-11-09 | — | — | WO | disclosed |