SCHEMBL17044643

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5368249	0.88	CA2 (0.43)	TDP1CA2CA1CA12CA9
	SCHEMBL8083823	0.82	HTR6 (0.53)	TDP1CA2CA1CA12CA9
	SCHEMBL2881343	0.82	TRPA1 (0.40)	TDP1CA2CA1CA12CA9
	SCHEMBL1919298	0.78	CA2 (0.67)	CA2CA1CA12CA9CA4
	SCHEMBL1738692	0.78	ENPP2 (0.46)	TDP1CA2CA1CA12CA9
	SCHEMBL7772184	0.78	F2 (0.64)	TDP1CA2CA1CA12CA9
	SCHEMBL314445	0.78	LMNA (0.48)	TDP1CA2CA1CA12CA9
	SCHEMBL313925	0.78	ALDH1A1 (0.44)	TDP1CA2CA1CA12CA9
	SCHEMBL30968190	0.78	LMNA (0.48)	TDP1CA2CA1CA12CA9
	SCHEMBL4101241	0.78	CA2 (0.67)	TDP1CA2CA1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.