Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Butadiene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butadiene SCHEMBL27493774 | 1.00 | — | — | |
| Butadiene SCHEMBL8849434 | 1.00 | TRPA1 (0.40) | — | |
| Butadiene SCHEMBL11246759 | 1.00 | — | — | |
| Butadiene SCHEMBL8849444 | 1.00 | TRPA1 (0.40) | — | |
| Butadiene SCHEMBL11246756 | 1.00 | TRPA1 (0.40) | — | |
| Butadiene SCHEMBL8721369 | 0.93 | — | — | |
| Butadiene SCHEMBL4444276 | 0.93 | — | — | |
| Butadiene SCHEMBL346636 | 0.93 | — | — | |
| Butadiene SCHEMBL10907342 | 0.93 | — | — | |
| Butadiene SCHEMBL3793988 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539689-A | Preparation method of variable frequency cable | 广东新亚光电缆股份有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-114446532-A | Production method of medium-voltage fire-resistant cable | 广东新亚光电缆股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-108948273-A | A kind of butadiene-haloflex-styrene-grafted copolymer rubber and preparation method thereof | 潍坊硕邑化学有限公司 | 2018-12-07 | — | — | CN | claimed |
| CN-108690282-A | Heat-insulated polyvinyl chloride-butadiene rubber composite cable sheath and preparation method thereof | 芜湖航天特种电缆厂股份有限公司 | 2018-10-23 | — | — | CN | claimed |
| CN-101421099-B | Acrylic rubber-metal composite body | NOK CORP | 2012-06-20 | — | — | CN | claimed |
| CN-101512199-A | Bonded piston seal | NOK CORP (JP) | 2009-08-19 | — | — | CN | claimed |
| CN-101421099-A | Acrylic rubber-metal composite body | NOK CORP (JP) | 2009-04-29 | — | — | CN | claimed |
| US-20070299167-A1 | Two-part bio-based furfuryl adhesive composition for engineered wood | AQUALON COMPANY | 2007-12-27 | — | — | US | claimed |
| WO-2007149589-A2 | TWO-PART BIO-BASED FURFURYL ADHESIVE COMPOSITION FOR ENGINEERED WOOD | ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) | 2007-12-27 | — | — | WO | claimed |
| EP-1501548-A4 | CHEMICALLY ACTIVATED CARBOXYPOLYSACCHARIDES AND USES | FZIOMED INC (US) | 2007-10-03 | — | — | EP | claimed |
| US-20030012896-A1 | Oxygen scavenging polymers in rigid polyethylene terephthalate beverage and food containers | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2003-01-16 | — | — | US | claimed |
| US-6454965-B1 | SELECTIVELY OXIDIZE UPON ACTIVATION WITHOUT GIVING OFF ODOROUS FRAGMENTS; CONDENSATION POLYMER DERIVED FROM CYCLIC HYDROCARBON MONOMERS HAVING AT LEAST ONE CYCLIC ALLYLIC AND A TRANSITION METAL OXIDATION CATALYST | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2002-09-24 | — | — | US | claimed |
| EP-1066337-A2 | OXYGEN SCAVENGERS WITH REDUCED OXIDATION PRODUCTS FOR USE IN PLASTIC FILMS AND BEVERAGE AND FOOD CONTAINERS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2001-01-10 | — | — | EP | claimed |
| WO-1999048963-A2 | OXYGEN SCAVENGERS WITH REDUCED OXIDATION PRODUCTS FOR USE IN PLASTIC FILMS AND BEVERAGE AND FOOD CONTAINERS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 1999-09-30 | — | — | WO | claimed |
| EP-0679698-B1 | Multicoloured flakes, process for their manufacture and decorative product using the said flakes | QUADRA IND SARL (FR) | 1998-07-15 | — | — | EP | claimed |
| CN-1099695-A | A method for manufacturing high-performance midsoles | KOREA INST OF FOOTWEAR TECHNOL (KR) | 1995-03-08 | — | — | CN | claimed |
| US-4233252-A | Butadiene chlorination process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-11-11 | — | — | US | claimed |
| EP-0001301-B1 | PRODUCTION OF A MIXTURE OF DICHLOROBUTENES FROM BUTADIENE AND CHLORINE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-08-20 | — | — | EP | claimed |
| EP-0001301-A1 | Production of a mixture of dichlorobutenes from butadiene and chlorine | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-04 | — | — | EP | claimed |
| US-4100250-A | HYDROMETALLURGY | COMINCO LTD. (CA) | 1978-07-11 | — | — | US | claimed |