Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.36 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL27603489 | 1.00 | ZDHHC20 (0.48) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Trimethylammonium SCHEMBL17223773 | 0.98 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL28468701 | 0.92 | TSHR (0.54) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL522224 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL28468699 | 0.92 | TSHR (0.54) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL108752 | 0.89 | — | — | |
| Trimethylammonium SCHEMBL27603492 | 0.89 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Bromide SCHEMBL3808860 | 0.87 | — | — | |
| Trimethylammonium SCHEMBL27623503 | 0.87 | ZDHHC20 (0.49) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Alcohol SCHEMBL28414613 | 0.86 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115210270-B | Film and use thereof | 富士胶片制造欧洲有限公司 | 2024-06-04 | — | — | CN | disclosed |
| US-20230138382-A1 | Membranes and Their Uses | FUJIFILM MANUFACTURING EUROPE B.V. (NL) | 2023-05-04 | — | — | US | disclosed |
| US-20230107868-A1 | Membranes and Their Uses | FUJIFILM MANUFACTURING EUROPE B.V. (NL) | 2023-04-06 | — | — | US | disclosed |
| EP-2734292-B1 | ION EXCHANGE MEMBRANES | FUJIFILM MFG EUROPE BV (NL) | 2021-11-03 | — | — | EP | disclosed |
| WO-2021198419-A1 | MEMBRANES AND THEIR USES | FUJIFILM MANUFACTURING EUROPE BV (NL) | 2021-10-07 | — | — | WO | disclosed |
| WO-2021198416-A1 | MEMBRANES AND THEIR USES | FUJIFILM MANUFACTURING EUROPE BV (NL) | 2021-10-07 | — | — | WO | disclosed |
| EP-3322748-B1 | ION EXCHANGE MEMBRANES | FUJIFILM MFG EUROPE BV (NL) | 2021-01-13 | — | — | EP | disclosed |
| EP-3322749-B1 | ION EXCHANGE MEMBRANES | FUJIFILM MFG EUROPE BV (NL) | 2020-10-07 | — | — | EP | disclosed |
| US-10633499-B2 | Process for preparing membranes | FUJIFILM MANUFACTURING EUROPE B.V. (NL) | 2020-04-28 | — | — | US | disclosed |
| US-10597502-B2 | Ion exchange membranes | FUJIFILM MANUFACTURING EUROPE B.V. (NL) | 2020-03-24 | — | — | US | disclosed |
| US-20120248029-A1 | Curable Compositions And Membranes | FUJIFILM MANUFACTURING EUROPE BV (NL) | 2012-10-04 | — | — | US | disclosed |
| CN-102686621-A | Curable compositions and membranes | FUJIFILM MFG EUROPE BV | 2012-09-19 | — | — | CN | disclosed |
| EP-2350150-B1 | CURABLE COMPOSITIONS AND MEMBRANES | FUJIFILM MFG EUROPE BV (NL) | 2012-08-22 | — | — | EP | disclosed |
| WO-2012085541-A2 | INKS & PRINTING PROCESS | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2012-06-28 | — | — | WO | disclosed |
| EP-2361271-A1 | CURABLE COMPOSITIONS AND MEMBRANES | Fujifilm Manufacturing Europe BV (NL) | 2011-08-31 | — | — | EP | disclosed |
| EP-2361270-A1 | CURABLE COMPOSITIONS AND MEMBRANES | Fujifilm Manufacturing Europe BV (NL) | 2011-08-31 | — | — | EP | disclosed |
| EP-2350150-A1 | CURABLE COMPOSITIONS AND MEMBRANES | Fujifilm Manufacturing Europe BV (NL) | 2011-08-03 | — | — | EP | disclosed |
| WO-2011073641-A1 | CURABLE COMPOSITIONS AND MEMBRANES | FUJIFILM MANUFACTURING EUROPE BV (NL) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011073640-A1 | CURABLE COMPOSITIONS AND MEMBRANES | FUJIFILM MANUFACTURING EUROPE BV (NL) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011073638-A1 | CURABLE COMPOSITIONS AND MEMBRANES | FUJIFILM MANUFACTURING EUROPE BV (NL) | 2011-06-23 | — | — | WO | disclosed |