Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Carbamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL3845940 | 1.00 | — | — | |
| Carbamic Acid SCHEMBL11241925 | 1.00 | — | — | |
| Carbamic Acid SCHEMBL18765304 | 1.00 | — | — | |
| Carbamic Acid SCHEMBL460108 | 1.00 | — | — | |
| Carbamic Acid SCHEMBL10506103 | 0.94 | — | — | |
| Carbamic Acid SCHEMBL28194568 | 0.94 | — | — | |
| Carbamic Acid SCHEMBL10802450 | 0.94 | — | — | |
| Carbamic Acid SCHEMBL27930001 | 0.94 | — | — | |
| Carbamic Acid SCHEMBL15667943 | 0.94 | — | — | |
| Carbamic Acid SCHEMBL27335487 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240425517-A1 | NOVEL COMPOUND FOR DEGRADATION OF TARGET PROTEIN OR POLYPEPTIDE BY POLYUBIQUITINATION | PRAZER THERAPEUTICS INC. (KR) | 2024-12-26 | — | — | US | claimed |
| CN-117903078-A | Amide derivative containing 3, 4-dichloro isothiazole, preparation method and application thereof | 南开大学 | 2024-04-19 | — | — | CN | claimed |
| CN-117430539-A | Preparation method of lactam and obtained product | 中国石油化工股份有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-114634509-A | Full continuous flow preparation method of (-) -tetrahydroberberine alkaloid | 复旦大学 | 2022-06-17 | — | — | CN | claimed |
| US-20220010068-A1 | POLY(2-OXAZOLINE)S AND METHODS FOR PREPARING THEM | UNIVERSITEIT GENT (BE) | 2022-01-13 | — | — | US | claimed |
| EP-3880181-A1 | POLY(2-OXAZOLINE)S AND METHODS FOR PREPARING THEM | Universiteit Gent (BE) | 2021-09-22 | — | — | EP | claimed |
| WO-2021122625-A1 | METHOD FOR PRODUCING DI- AND POLYISOCYANATES OF THE DIPHENYLMETHANE SERIES | COVESTRO DEUTSCHLAND AG (DE) | 2021-06-24 | — | — | WO | claimed |
| WO-2020099553-A1 | POLY(2-OXAZOLINE)S AND METHODS FOR PREPARING THEM | UNIVERSITEIT GENT (BE) | 2020-05-22 | — | — | WO | claimed |
| EP-3652177-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES AS CHOLINE KINASE INHIBITORS | Nerviano Medical Sciences S.r.l. (IT) | 2020-05-20 | — | — | EP | claimed |
| CN-110343122-A | A kind of preparation method of Biapenem | 山东罗欣药业集团股份有限公司 | 2019-10-18 | — | — | CN | claimed |
| EP-0000021-B1 | PROCESS FOR THE PREPARATION OF SULFONIC ACID GROUPS AND PHOSPHONATE GROUPS BEARING POLYISOCYANATE MIXTURES | BAYER AG (DE) | 1980-07-23 | — | — | EP | claimed |
| US-4195032-A | Process for continuously working up solutions of the type accumulating in the phosgenation of monoamines | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-25 | — | — | US | claimed |
| US-4177206-A | FIREPROOFING | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | claimed |
| US-4153764-A | Process for the production of polyisocyanate organic silicate solid/cellular solid product | BLOUNT DAVID H | 1979-05-08 | — | — | US | claimed |
| US-4146550-A | REACTION OF CARBAMIC ACID CHLORIDE WITH ACTIVE HYDROGEN COMPOUND, DECOMPOSITION | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-27 | — | — | US | claimed |
| US-4088665-A | Process for the partial carbodiimidization of organic isocyanates | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | claimed |
| US-4051165-A | Preparation of biuret polyisocyanates | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | claimed |
| US-4045479-A | Process of preparing penicillamine | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-08-30 | — | — | US | claimed |
| US-3981831-A | REACTION OF ORGANIC POLYISOCYANATE WITH ALKALI METAL SILICATE OR SILICA SOL | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-21 | — | — | US | claimed |
| US-3957756-A | PREPARATION OF SUBSTITUTED UREAS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | claimed |