Carbamic Acid

Carbamic Acid

SCHEMBL460108

Cl.Cl.NC(=O)O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Carbamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110300759-A The new compound of anti-mycobacteria 悉尼大学 2019-10-01 CN claimed
CN-109758468-A Medical usage of the N- benzene substitution -2- hypoxanthine sulfenyl acetamide derivative in Killing Mycobacterium Tuberculosis infection 中国药科大学 2019-05-17 CN claimed
CN-108314065-A Divide the full membrane separating method that salt produces lithium liquor by salt lake bittern multistage nanofiltration 陕西省膜分离技术研究院有限公司 2018-07-24 CN claimed
CN-106860468-A A kind of formula for treating phthisical pharmaceutical composition and preparation method thereof 新乡医学院第附属医院 2017-06-20 CN claimed
EP-3154983-A1 SOLID FORMS OF AN ANTIVIRAL COMPOUND Gilead Pharmasset LLC (US) 2017-04-19 EP claimed
CN-104772160-B A kind of carbonitride photocatalytic activity nano fibrous membrane and preparation method thereof 北京师范大学 2017-03-15 CN claimed
WO-2015191431-A1 SOLID FORMS OF AN ANTIVIRAL COMPOUND GILEAD PHARMASSET LLC (US) 2015-12-17 WO claimed
CN-104772160-A Carbon nitride photocatalytic activity nano fiber membrane and preparation method thereof UNIV BEIJING NORMAL 2015-07-15 CN claimed
US-8829028-B2 5-HT4 receptor antagonists for the treatment of heart failure SERODUS AS (NO) 2014-09-09 US claimed
CN-102633737-A Synthesis of triazine amide organic acid JIANDONG XIU 2012-08-15 CN claimed
CN-102559844-A Preparation method of detecting system for minimal inhibitory concentration of mycobacteria UNIV SHANGHAI JIAOTONG 2012-07-11 CN claimed
CN-102491952-A Synthesis process of triazine amide SICHUAN LESHAN FUHUA TONGDA AGRO CHEMICAL TECHNOLOGY CO LTD 2012-06-13 CN claimed
CN-102380107-A Method for detecting whether patient is allergic to medicine UNIV PLA 3RD MILITARY MEDICAL 2012-03-21 CN claimed
CN-102188655-A Molecular Chinese patent medicine for inhibiting defects of Lifei tablets and syndromes of pulmonary tuberculosis MIN YANG 2011-09-21 CN claimed
US-20090169545-A1 5-HT4 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF HEART FAILURE SERODUS AS (NO) 2009-07-02 US claimed
US-20060094715-A1 5-Ht4 receptor antagonists for the treatment of heart failure SERODUS AS (NO) 2006-05-04 US claimed
CN-1644536-A Surface active agent waste water rapid treating, circulating and recovering method UNIV SHANGHAI COMMUNICATION (CN) 2005-07-27 CN claimed
CN-1297352-A Use of organophosphorous compounds for the therapeutic and prophylactic treatment of infections HASSAN JOMAA (DE) 2001-05-30 CN claimed
CN-122074043-A Combination therapy with KRAS modulators 光达治疗公司 2026-05-22 CN disclosed
US-3947484-A Continuous prephosgenation process for the production of organic isocyanates BAYER AKTIENGESELLSCHAFT (DT) 1976-03-30 US disclosed