Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2123128

CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)Cc1cccc(C)c1C.Cl

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCHE known ✓ P06276 5/20 0.43
ACHE known ✓ P22303 3/20 0.43
ESR1 known ✓ P03372 1/20 0.43
ESR2 known ✓ Q92731 1/20 0.43
KCNH2 known ✓ Q12809 4/20 0.41
GAA known ✓ P10253 1/20 0.40
DRD2 known ✓ P14416 1/20 0.38
OPRM1 known ✓ P35372 1/20 0.38
DRD3 known ✓ P35462 1/20 0.38
OPRD1 known ✓ P41143 1/20 0.38
OPRK1 known ✓ P41145 1/20 0.38
MAPT P10636 3/20 0.46
ALDH1A1 P00352 3/20 0.40
THRB P10828 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MAPK1 P28482 1/20 0.39
MCHR1 Q99705 1/20 0.38
TP53 P04637 1/20 0.38
ICMT O60725 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3131665 1.00 MAPT (0.46) MAPTBCHEACHEESR1ESR2
Hydrochloric Acid SCHEMBL6894428 1.00 MAPT (0.46) MAPTBCHEACHEESR1ESR2
Hydrochloric Acid SCHEMBL6892141 1.00 MAPT (0.46) MAPTBCHEACHEESR1ESR2
Hydrochloric Acid SCHEMBL6894361 1.00 MAPT (0.46) MAPTBCHEACHEESR1ESR2
Hydrochloric Acid SCHEMBL4137773 1.00 MAPT (0.46) MAPTBCHEACHEESR1ESR2
Hydrochloric Acid SCHEMBL11235728 1.00 MAPT (0.46) MAPTBCHEACHEESR1ESR2
SCHEMBL6574866 0.98 BCHE (0.44) MAPTBCHEACHEESR1ESR2
SCHEMBL9579609 0.98 BCHE (0.44) MAPTBCHEACHEESR1ESR2
SCHEMBL1836537 0.98 BCHE (0.44) MAPTBCHEACHEESR1ESR2
SCHEMBL1472901 0.98 BCHE (0.44) MAPTBCHEACHEESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1812149-B1 SEMIPERMEABLE COMPOSITE MEMBRANE, PRODUCTION PROCESS THEREOF AND TREATMENT METHOD FOR BORON-CONTAINING WATER TORAY INDUSTRIES (JP) 2013-06-12 EP claimed
EP-3550030-B1 METHOD FOR MEASURING GLYCATION RATE OF HEMOGLOBIN TOYO BOSEKI (JP) 2025-01-01 EP disclosed
US-11567076-B2 Method for detecting coliform bacteria contained in milk ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-01-31 US disclosed
CN-115536035-A Preparation method of temperature-resistant organic bentonite, temperature-resistant organic bentonite and application thereof 中石化南京化工研究院有限公司 2022-12-30 CN disclosed
CN-109957201-B Nano high-toughness PS composite material and preparation method thereof 江西固康新材料有限公司 2021-12-14 CN disclosed
US-10908160-B2 Method for detecting Streptococcus bacterium contained in milk ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-02-02 US disclosed
US-10732179-B2 Method for detecting Staphylococcus contained in milk ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-08-04 US disclosed
EP-3085769-B1 METHOD FOR DETECTING COLIFORM BACTERIA CONTAINED IN MILK ASAHI CHEMICAL IND (JP) 2020-04-15 EP disclosed
US-20200103405-A1 METHOD FOR DETECTING STREPTOCOCCUS BACTERIUM CONTAINED IN MILK ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-04-02 US disclosed
EP-3025811-B1 METALLIC COPPER DISPERSION, METHOD FOR MANUFACTURING SAME, AND USAGE FOR SAME ISHIHARA SANGYO KAISHA (JP) 2020-03-11 EP disclosed
EP-1518534-B1 Bilayered cosmetic product, uses thereof and kit-of-parts containing this product. OREAL (FR) 2010-07-14 EP disclosed
US-20100029503-A1 ANALYSIS CHIP AND ANALYSIS METHOD TORAY INDUSTRIES, INC. (JP) 2010-02-04 US disclosed
US-7641054-B2 Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and treatment method for boron-containing water using the same TORAY INDUSTRIES, INC. (JP) 2010-01-05 US disclosed
EP-2107373-A1 ANALYSIS CHIP AND ANALYSIS METHOD Toray Industries, Inc. (JP) 2009-10-07 EP disclosed
US-20090004125-A1 polymers obtained by polymerization of methyl acrylate and of at least one polyethylene/polybutylene macromonomer comprising at least one methacrylate end group L'OREAL (FR) 2009-01-01 US disclosed
US-20080000843-A1 Composite Semipermeable Membrane, Production Process Thereof, and Element, Fluid Separation Equipment and Treatment Method for Boron-Containing Water Using the Same TORAY INDUSTRIES, INC. (JP) 2008-01-03 US disclosed
EP-1812149-A1 COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND TREATMENT METHOD FOR BORON-CONTAINING WATER USING THE SAME TORAY INDUSTRIES, INC. (JP) 2007-08-01 EP disclosed
WO-2006051888-A1 COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND TREATMENT METHOD FOR BORON-CONTAINING WATER USING THE SAME TORAY INDUSTRIES, INC. (JP) 2006-05-18 WO disclosed
US-20050095213-A1 Two-coat cosmetic product, cosmetic process of using thereof and makeup kit containing this product L'OREAL S.A. (FR) 2005-05-05 US disclosed
US-20040029758-A1 Method of circulating water in circulatory water tank system and liquid composition for sterilizing and disinfecting circulatory water tank system LEGIOTEC CO., LTD. (JP) 2004-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050095213-A1 Two-coat cosmetic product, cosmetic process of using thereof and makeup kit containing this product CUTA, PRKACB, PRKDC BCHE 2861/4885ACHE 2328/4885ESR1 2085/4885
US-20090004125-A1 polymers obtained by polymerization of methyl acrylate and of at least one polyethylene/polybutylene macromonomer comprising at least one methacrylate end group MMAB, DNMT1, TET1 BCHE 3465/4885ACHE 3405/4885ESR1 1822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.