Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.40 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5693995 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPTTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL5693996 | 1.00 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPTTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL28960108 | 0.96 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1MAPTTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL29183626 | 0.96 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1MAPTTDP1KDM4E | |
| Benzene SCHEMBL28083527 | 0.96 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1MAPTTDP1KDM4E | |
| SCHEMBL453160 | 0.96 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1MAPTTDP1KDM4E | |
| SCHEMBL30959 | 0.96 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1MAPTTDP1KDM4E | |
| SCHEMBL9490577 | 0.96 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1MAPTTDP1KDM4E | |
| Methane SCHEMBL23501806 | 0.92 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPTTDP1KDM4E | |
| SCHEMBL36869 | 0.92 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1MAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385887-B | Method for preparing isoxadifen by catalyzing cyclization reaction through ammonium salt ionic liquid | 北京联本医药化学技术有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-117210976-A | High-whiteness viscose fiber spinning oil and preparation method thereof | 乌鲁木齐市华泰隆化学助剂有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-115385887-A | Method for preparing isoxepac by ammonium salt ionic liquid catalytic cyclization reaction | 北京联本医药化学技术有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-102585097-B | Method for preparing amphoteric starch | UNIV HENAN TECHNOLOGY | 2013-06-12 | — | — | CN | claimed |
| CN-102585097-A | Method for preparing amphoteric starch | UNIV HENAN TECHNOLOGY | 2012-07-18 | — | — | CN | claimed |
| CN-101385185-B | Rechargeable lithium-ion cell with triphenylamine redox shuttle | 3M INNOVATIVE PROPERTIES CO | 2011-05-04 | — | — | CN | claimed |
| CN-101385185-A | Rechargeable lithium-ion cell with triphenylamine redox shuttle | 3M INNOVATIVE PROPERTIES CO (US) | 2009-03-11 | — | — | CN | claimed |
| CN-1966501-A | Dendriform acetal ketal compound containing oxy, sulf heteroatom and its preparation method | UNIV TIANJIN TECHNOLOGY (CN) | 2007-05-23 | — | — | CN | claimed |
| US-6319649-B1 | CAN FORM PATTERN WITH HIGH SENSITIVITY, RESOLUTION ABILITY AND STABILITY, ACCURACY | HITACHI, LTD. (JP) | 2001-11-20 | — | — | US | claimed |
| US-5147621-A | Amine stabilizer | CHEMIE AG BITTERFELD-WOLFEN (DE) | 1992-09-15 | — | — | US | claimed |
| CN-118164937-A | Method for preparing 5-acetyl-2, 3-phenylpropanoid dihydrofuran by ammonium salt ionic liquid catalysis | 北京联本医药化学技术有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-115385887-B | Method for preparing isoxadifen by catalyzing cyclization reaction through ammonium salt ionic liquid | 北京联本医药化学技术有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-117210976-A | High-whiteness viscose fiber spinning oil and preparation method thereof | 乌鲁木齐市华泰隆化学助剂有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-115385887-A | Method for preparing isoxepac by ammonium salt ionic liquid catalytic cyclization reaction | 北京联本医药化学技术有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-112770779-B | Cellulose composition, tablet and orally disintegrating tablet | 旭化成株式会社 | 2022-07-22 | — | — | CN | disclosed |
| EP-0000757-B1 | PROCESS FOR THE PREPARATION OF TRIARYLPHOSPHITES | CIBA-GEIGY AG (CH) | 1981-08-05 | — | — | EP | disclosed |
| US-4251469-A | ADDITIVES FOR EXTREME PRESSURE LUBRICANTS | CIBA-GEIGY CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
| US-4197209-A | Lubricant compositions containing sulfur-containing esters of phosphoric acid | CIBA-GEIGY CORPORATION (US) | 1980-04-08 | — | — | US | disclosed |
| US-4189453-A | FROM MERCAPTANS AND PHOSPHORUS TRIHALIDE, CATALYTIC | CIBA-GEIGY CORPORATION (US) | 1980-02-19 | — | — | US | disclosed |
| EP-0000757-A1 | Process for the preparation of triarylphosphites | CIBA-GEIGY AG (CH) | 1979-02-21 | — | — | EP | disclosed |