Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 4/20 | 0.31 |
| ▸ | RET known ✓ | P07949 | 1/20 | 0.31 |
| ▸ | HTR6 known ✓ | P50406 | 1/20 | 0.30 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9719951 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL4457343 | 0.77 | KDM4E (0.40) | SIGMAR1RETHTR6KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL8927723 | 0.76 | — | — | |
| SCHEMBL6857385 | 0.75 | RET (0.38) | SIGMAR1RETHTR6KDM4EMEN1 | |
| SCHEMBL29480066 | 0.75 | RET (0.38) | SIGMAR1RETHTR6KDM4EMEN1 | |
| SCHEMBL3685967 | 0.75 | HTR2A (0.38) | SIGMAR1RETHTR6KDM4EMEN1 | |
| SCHEMBL29697103 | 0.75 | HTR2A (0.38) | SIGMAR1RETHTR6KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7628976 | 0.74 | RET (0.35) | SIGMAR1RETHTR6KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7641689 | 0.74 | RET (0.35) | SIGMAR1RETHTR6KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7615277 | 0.74 | RET (0.35) | SIGMAR1RETHTR6KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223822-B2 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-29 | — | — | US | claimed |
| EP-1753796-A1 | MULTIPLE CATALYST AND REACTOR SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM | ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) | 2007-02-21 | — | — | EP | claimed |
| WO-2005113622-A1 | MULTIPLE CATALYST AND REACTOR SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-12-01 | — | — | WO | claimed |
| US-20040220359-A1 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-11-04 | — | — | US | claimed |
| US-10421921-B2 | Lubricants from mixed alpha-olefin feeds | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2019-09-24 | — | — | US | disclosed |
| EP-1920031-B1 | LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2018-01-10 | — | — | EP | disclosed |
| US-20170137737-A1 | Lubricants from Mixed Alpha-Olefin Feeds | EXXONMOBIL CHEMICAL PATENTS INC. | 2017-05-18 | — | — | US | disclosed |
| US-9593288-B2 | Lubricants from mixed alpha-olefin feeds | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-20150252279-A1 | Lubricants From Mixed Alpha-Olefin Feeds | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-09-10 | — | — | US | disclosed |
| US-8957159-B2 | Multiple catalyst system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-02-17 | — | — | US | disclosed |
| US-8921291-B2 | Lubricants from mixed alpha-olefin feeds | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20140378720-A1 | Processes to Produce Polyalpha-Olefin Compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2014-12-25 | — | — | US | disclosed |
| US-6403181-B1 | CONDUITS MADE FROM POLYETHYLENE MIXTURES HAVING BIMODAL MOLECULAR WEIGHT DISTRIBUTION, HIGH MOLECULAR WEIGHT AND HIGH VISCOSITY; IMPACT/TENSILE STRENGTH; VIABILITY | MOBIL OIL CORPORATION | 2002-06-11 | — | — | US | disclosed |
| WO-2002044222-A1 | BIMETALLIC CATALYST FOR PRODUCING POLYETHYLENE RESINS WITH BIMODAL MOLECULAR WEIGHT DISTRIBUTION, ITS PREPARATION AND USE | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2002-06-06 | — | — | WO | disclosed |
| EP-0977786-A4 | PREMIUM PIPE RESINS | MOBIL OIL CORP (US) | 2001-10-24 | — | — | EP | disclosed |
| EP-0881949-A4 | BIMETALLIC CATALYST FOR ETHYLENE POLYMERIZATION REACTIONS WITH UNIFORM COMPONENT DISTRIBUTION | MOBIL OIL CORP (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0977786-A1 | PREMIUM PIPE RESINS | MOBIL OIL CORPORATION (a New York corporation) (US) | 2000-02-09 | — | — | EP | disclosed |
| EP-0881949-A1 | BIMETALLIC CATALYST FOR ETHYLENE POLYMERIZATION REACTIONS WITH UNIFORM COMPONENT DISTRIBUTION | MOBIL OIL CORPORATION (US) | 1998-12-09 | — | — | EP | disclosed |
| WO-1998049209-A1 | PREMIUM PIPE RESINS | MOBIL OIL CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |
| WO-1997017136-A1 | BIMETALLIC CATALYST FOR ETHYLENE POLYMERIZATION REACTIONS WITH UNIFORM COMPONENT DISTRIBUTION | MOBIL OIL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378720-A1 | Processes to Produce Polyalpha-Olefin Compositions | AP1M1, AP1S1, CCT4 | SIGMAR1 1617/4885RET 1682/4885HTR6 2690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.