Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2231004

CCCCNCCCC.Cl

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA known ✓ P06280 1/20 0.53
CA2 known ✓ P00918 1/20 0.43
S1PR2 known ✓ O95136 5/20 0.42
S1PR4 known ✓ O95977 5/20 0.42
S1PR1 known ✓ P21453 5/20 0.42
S1PR3 known ✓ Q99500 5/20 0.42
S1PR5 known ✓ Q9H228 1/20 0.42
SIGMAR1 known ✓ Q99720 1/20 0.41
TSHR P16473 4/20 0.73
ALDH1A1 P00352 1/20 0.73
CYP2C19 P33261 2/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
ADH1B P00325 2/20 0.50
ADH1C P00326 2/20 0.50
ADH1A P07327 2/20 0.50
ADH7 P40394 2/20 0.50
CYP1A2 P05177 1/20 0.50
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6233205 1.00 TSHR (0.73) TSHRALDH1A1CYP2C19MEN1GLA
Ethane SCHEMBL28459729 0.96 TSHR (0.69) TSHRALDH1A1CYP2C19MEN1GLA
Hydrochloric Acid SCHEMBL11805112 0.96 TSHR (0.69) TSHRALDH1A1CYP2C19MEN1GLA
Hydrochloric Acid SCHEMBL8024908 0.96 TSHR (0.69) TSHRALDH1A1CYP2C19MEN1GLA
Hydrochloric Acid SCHEMBL11561356 0.96 TSHR (0.69) TSHRALDH1A1CYP2C19MEN1GLA
SCHEMBL2532 0.96
SCHEMBL27946380 0.96 TSHR (0.79) TSHRALDH1A1CYP2C19MEN1GLA
Hydrochloric Acid SCHEMBL9058503 0.93 TSHR (0.65) TSHRALDH1A1CYP2C19MEN1GLA
Hydrochloric Acid SCHEMBL22771571 0.93 TSHR (0.87) TSHRALDH1A1CYP2C19MEN1GLA
Hydrochloric Acid SCHEMBL22771814 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122054812-A Photoelectric device and preparation method thereof, electricity utilization device and electricity generation device 宁德时代新能源科技股份有限公司 2026-05-15 CN claimed
CN-119409726-A Efficient preparation method of antioxidant 168 湖北兴发化工集团股份有限公司 2025-02-11 CN claimed
CN-119080022-A Lamellar AEL molecular sieve and preparation method and application thereof 聊城大学 2024-12-06 CN claimed
CN-119081535-A Polyurethane composite super-hydrophobic coating and preparation method thereof 浙江锋凌新材料科技有限公司 2024-12-06 CN claimed
CN-118271568-A Preparation method of high-functionality polyurethane acrylic ester crosslinking agent and crosslinking agent thereof 厦门大学 2024-07-02 CN claimed
CN-117900696-A Magnetic solder and preparation method and application thereof 云南科威液态金属谷研发有限公司 2024-04-19 CN claimed
CN-114085353-B Photo-thermal dual-curing resin and preparation method thereof 武汉中科先进材料科技有限公司 2023-08-11 CN claimed
CN-113666833-B Preparation method of environment-friendly rosinyl quaternary ammonium salt antibacterial agent 浙江理工大学 2022-08-30 CN claimed
CN-112552870-B High-strength high-hardness UV/moisture dual-curing MS glue and preparation method thereof 烟台信友新材料有限公司 2022-08-02 CN claimed
CN-112745474-B Preparation method of all-solid-state polymer electrolyte and prepared product 合肥国轩高科动力能源有限公司 2022-06-07 CN claimed
US-6579835-B2 From cationic oligourethanes based on branched and thermocrosslinkable (per)fluoropolyethers AUSIMONT S.P.A. (IT) 2003-06-17 US claimed
US-20020016267-A1 Polyurethanes having a low friction coefficient AUSIMONT S.P.A. 2002-02-07 US claimed
US-20020016505-A1 Heat storage material having solid/solid phase transition remains solid through application; heat resistance; materials handling MERCK PATENT GMBH (DE) 2002-02-07 US claimed
EP-1162220-A1 Polyurethanes having a low friction coefficient Ausimont S.p.A. (IT) 2001-12-12 EP claimed
EP-1148108-A1 Storage media for latent heat storage units MERCK PATENT GmbH (DE) 2001-10-24 EP claimed
EP-1059319-A2 Fluorinated oligourethanes Ausimont S.p.A. (IT) 2000-12-13 EP claimed
US-4863984-A STYRENE RESIN, AMINE SALT GENERAL ELECTRIC COMPANY (US) 1989-09-05 US claimed
EP-0305861-A1 Flame retardant extrudate of polyphenylene ether blends, and method of making GENERAL ELECTRIC COMPANY (US) 1989-03-08 EP claimed
US-4051165-A Preparation of biuret polyisocyanates BAYER AKTIENGESELLSCHAFT (DT) 1977-09-27 US claimed
US-4042605-A Process for the production of 1,4-diaminoanthraquinone-2,3-dinitrile BASF AKTIENGESELLSCHAFT (DT) 1977-08-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020016505-A1 Heat storage material having solid/solid phase transition remains solid through application; heat resistance; materials handling HSPH1, HSP90AA1, HSPA1A GLA 3327/4885CA2 2944/4885S1PR2 4334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.