Glycerin

Glycerin

SCHEMBL230009

Cl.OCC(O)CO

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL9653032 1.00 LMNA (0.90)
Glycerin SCHEMBL9653041 1.00
Glycerin SCHEMBL21768737 1.00
Glycerin SCHEMBL10974009 1.00 LMNA (0.90)
Glycerin SCHEMBL10979458 1.00 LMNA (0.90)
Glycerin SCHEMBL29033539 0.95
Glycerin SCHEMBL26626409 0.95
Glycerin SCHEMBL11026686 0.95
Glycerin SCHEMBL28694326 0.95
Glycerin SCHEMBL27756681 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114772682-B Gold-based modified electrode, method for removing chloroglycerol and application thereof 北京化工大学 2023-07-25 CN claimed
CN-115754047-A Method for detecting residual quantity of glycerin and glycerin chloride in glycerophosphorylcholine 中山百灵生物技术股份有限公司 2023-03-07 CN claimed
CN-115138382-A Flower-ball-shaped sulfur-doped carbon nitride catalyst for hydrogen production by visible light decomposition of water and preparation method thereof 宁波工程学院 2022-10-04 CN claimed
CN-115138384-A Flower-like molybdenum and sulfur co-doped three-dimensional carbon nitride catalyst for hydrogen production by visible light decomposition of water and preparation method thereof 宁波工程学院 2022-10-04 CN claimed
CN-115121273-A Three-dimensional thorn-shaped bismuth-doped carbon nitride catalyst for hydrogen production by visible light decomposition of water and preparation method thereof 宁波工程学院 2022-09-30 CN claimed
CN-114917944-A Double-spherical bismuth and sulfur co-doped carbon nitride catalyst for hydrogen production by visible light decomposition of water and preparation method thereof 宁波工程学院 2022-08-19 CN claimed
CN-114917945-A Carbon-rich hollow three-dimensional flower spherical carbon nitride catalyst for hydrogen production by visible light decomposition of water and preparation method thereof 宁波工程学院 2022-08-19 CN claimed
CN-114772682-A Gold-based modified electrode, method for removing glycerol oxychloride and application of gold-based modified electrode 北京化工大学 2022-07-22 CN claimed
CN-216630821-U Reation kettle is used in glycerin chlorohydrin production 江苏合泰新材料科技有限公司 2022-05-31 CN claimed
WO-2022075992-A1 SELF-WICKING DEVICES HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-04-14 WO claimed
CN-211635272-U Continuous production device for chiral epichlorohydrin and chiral glycerin chloride 湖南亚王医药科技有限公司 2020-10-09 CN claimed
CN-106358766-A High-survival-rate pomegranate grafting method 怀远县荆涂山石榴科技有限公司 2017-02-01 CN claimed
CN-102171198-B Method for producing epichlorohydrin from glycerol KANZLER WALTER 2013-08-07 CN claimed
CN-102675047-A Method for preparing dichloropropanol XI AN HANSHU CHEMICAL ENGINEERING CO LTD 2012-09-19 CN claimed
US-20120035380-A1 PROCESS FOR PREPARING EPICHLOROHYDRIN FROM GLYCEROL KANZLER WALTER (AT) 2012-02-09 US claimed
CN-102295529-A Method for continuously preparing dichlorohydrin by using glycerin and hydrochloric acid 2011-12-28 CN claimed
US-7694628-B2 Method of producing energetically-inert pseudoscents of explosive materials, and compositions thereof GMA INDUSTRIES (US) 2010-04-13 US claimed
CN-101541418-A Conversion of glycerine to dichlorohydrins and epichlorohydrin CONSER SPA 2009-09-23 CN claimed
WO-2007108797-A2 A METHOD OF PRODUCING ENERGETICALLY-INERT PSEUDOSCENTS OF EXPLOSIVE MATERIALS, AND COMPOSITIONS THEREOF GMA INDUSTRIES (US) 2007-09-27 WO claimed
US-20070221087-A1 Method of producing energetically-inert pseudoscents of explosive materials, and compositions thereof GMA INDUSTRIES 2007-09-27 US claimed