Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 known ✓ | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.48 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.48 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.48 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.48 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.48 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.48 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.48 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.48 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.90 |
| ▸ | TSHR | P16473 | 2/20 | 0.90 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.67 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL782950 | 1.00 | ALDH1A1 (0.90) | ALDH1A1TSHRTAAR1AOC3HRH3 | |
| Hydrochloric Acid SCHEMBL6391891 | 0.97 | TSHR (0.94) | ALDH1A1TSHRTAAR1AOC3HRH3 | |
| Hydrochloric Acid SCHEMBL8743641 | 0.97 | TSHR (0.94) | ALDH1A1TSHRTAAR1AOC3HRH3 | |
| Hydrochloric Acid SCHEMBL22132 | 0.97 | TSHR (0.94) | ALDH1A1TSHRTAAR1AOC3HRH3 | |
| Water SCHEMBL4609382 | 0.97 | ALDH1A1 (0.94) | ALDH1A1TSHRTAAR1AOC3HRH3 | |
| Hydrochloric Acid SCHEMBL28352413 | 0.97 | TSHR (0.94) | ALDH1A1TSHRTAAR1AOC3HRH3 | |
| Hydrochloric Acid SCHEMBL7039469 | 0.95 | TSHR (0.90) | ALDH1A1TSHRTAAR1AOC3HRH3 | |
| Methane SCHEMBL28616286 | 0.95 | TSHR (0.90) | ALDH1A1TSHRTAAR1AOC3HRH3 | |
| Hydrochloric Acid SCHEMBL7039464 | 0.95 | TSHR (0.90) | ALDH1A1TSHRTAAR1AOC3HRH3 | |
| Hydrochloric Acid SCHEMBL28015782 | 0.95 | TSHR (0.90) | ALDH1A1TSHRTAAR1AOC3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240058434-A1 | NANOEMULSION UNIVERSAL INFLUENZA VACCINE | BLUEWILLOW BIOLOGICS, INC. (US) | 2024-02-22 | — | — | US | claimed |
| WO-2023200764-A1 | NANOEMULSION UNIVERSAL INFLUENZA VACCINE | BLUEWILLOW BIOLOGICS, INC. (US) | 2023-10-19 | — | — | WO | claimed |
| WO-2023133143-A1 | INTRANASAL POLYSACCHARIDE CONJUGATE NANOEMULSION VACCINES AND METHODS OF USING THE SAME | BLUEWILLOW BIOLOGICS, INC. (US) | 2023-07-13 | — | — | WO | claimed |
| US-20200246449-A1 | INTRAVENOUS IMMUNOGLOBULIN COMPOSITIONS SPECIFIC FOR RESPIRATORY SYNCYTIAL VIRUS AND METHODS OF MAKING AND USING THE SAME | NANOBIO CORPORATION (US) | 2020-08-06 | — | — | US | claimed |
| WO-2018204669-A1 | INTRAVENOUS IMMUNOGLOBULIN COMPOSITIONS SPECIFIC FOR RESPIRATORY SYNCYTIAL VIRUS AND METHODS OF MAKING AND USING THE SAME | NANOBIO CORPORATION (US) | 2018-11-08 | — | — | WO | claimed |
| CN-104876826-B | A kind of synthetic method of the double benzyl chlorides of renewable accelerant and application | 西南大学 | 2017-06-13 | — | — | CN | claimed |
| US-9492525-B2 | Human respiratory syncytial virus vaccine | NANOBIO CORPORATION (US) | 2016-11-15 | — | — | US | claimed |
| CN-103857484-B | The method preparing hollow metal nanometer particle and the hollow metal nanometer particle prepared by the method | LG化学株式会社 | 2016-06-08 | — | — | CN | claimed |
| CN-104884198-A | Method for manufacturing hollow metal nanoparticle supported by support body | LG CHEMICAL LTD | 2015-09-02 | — | — | CN | claimed |
| CN-104876826-A | Synthesis method and application of reproducible dyeing accelerant bisbenzyl dimethyl ammonia chloride | UNIV SOUTHWEST | 2015-09-02 | — | — | CN | claimed |
| CN-101237868-A | Nanoparticulate clopidogrel and aspirin combination formulations | ELAN PHARMA INT LTD (IE) | 2008-08-06 | — | — | CN | claimed |
| CN-101212954-A | Nanoparticulate clopidogrel formulations | ELAN PHARMA INT LTD (IE) | 2008-07-02 | — | — | CN | claimed |
| CN-101198314-A | Nanoparticulate quinazoline derivative formulations | ELAN PHARMA INT LTD (IE) | 2008-06-11 | — | — | CN | claimed |
| CN-101180038-A | Nanoparticulate corticosteroid and antihistamine formulations | ELAN PHARMA INT LTD (IE) | 2008-05-14 | — | — | CN | claimed |
| CN-101175481-A | Injectable compositions of nanoparticulate immunosuppressive compounds | ELAN PHARMA INT LTD (IE) | 2008-05-07 | — | — | CN | claimed |
| CN-101160118-A | Nanoparticulate formulations of docetaxel and analogues thereof | ELAN PHARMA INT LTD (IE) | 2008-04-09 | — | — | CN | claimed |
| CN-101132770-A | Nanoparticulate candesartan formulations | ELAN PHARMA INT LTD (IE) | 2008-02-27 | — | — | CN | claimed |
| CN-101090720-A | Nanoparticulate compositions of tubulin inhibitor compounds | BAXTER INT (US) | 2007-12-19 | — | — | CN | claimed |
| US-6197321-B1 | CONTAINING MICROBIAL SANITIZER AND HARDENER | ECOLAB, INC. | 2001-03-06 | — | — | US | claimed |
| US-5312624-A | Sanitizing drains by dispensing chemicals in housings | ECOLAB INC. (US) | 1994-05-17 | — | — | US | claimed |