Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.39 |
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.38 |
| ▸ | GRIN2D known ✓ | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B known ✓ | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 known ✓ | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A known ✓ | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B known ✓ | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C known ✓ | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A known ✓ | Q8TCU5 | 1/20 | 0.37 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 4/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | GGT1 | P19440 | 2/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23923852 | 1.00 | PTGS1 (0.39) | PTGS1SLC7A11NOS2CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL23923850 | 1.00 | PTGS1 (0.39) | PTGS1SLC7A11NOS2CYP1A2CYP2C19 | |
| SCHEMBL13539959 | 0.98 | — | — | |
| SCHEMBL13482801 | 0.98 | — | — | |
| SCHEMBL15525400 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL21437407 | 0.81 | NOS2 (0.46) | NOS2CYP1A2CYP2C19TSHRGLA | |
| Hydrochloric Acid SCHEMBL30809505 | 0.81 | NOS2 (0.46) | NOS2CYP1A2CYP2C19TSHRGLA | |
| SCHEMBL15103225 | 0.79 | SLC7A5 (0.48) | SLC7A5GRIK1GRIA1GRIA2SLC1A3 | |
| SCHEMBL14164385 | 0.78 | NOS2 (0.47) | NOS2CYP1A2CYP2C19TSHRGLA | |
| SCHEMBL14087200 | 0.78 | NOS2 (0.47) | NOS2CYP1A2CYP2C19TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023092715-A1 | ALANINE AGGREGATION-INDUCED EMISSION FLUORESCENT PROBE, AND SYNTHESIS METHOD THEREFOR AND USE THEREOF | 深圳先进技术研究院 | 2023-06-01 | — | — | WO | claimed |
| CN-116143749-A | Alanine aggregation-induced emission fluorescent probe and synthesis method and application thereof | 深圳先进技术研究院 | 2023-05-23 | — | — | CN | claimed |
| US-20250354192-A1 | METHODS FOR QUANTIFYING LIVE BACTERIA | ANCERA INC (US) | 2025-11-20 | — | — | US | disclosed |
| EP-4540404-A1 | METHODS FOR QUANTIFYING LIVE BACTERIA | Ancera Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| US-20250059581-A1 | METHOD OF BACTERIAL IDENTIFICATION AND TESTING OF BACTERIUM RESISTANT TO ONE OR MORE ANTIBIOTICS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2025-02-20 | — | — | US | disclosed |
| EP-4457354-A2 | METHOD OF BACTERIAL IDENTIFICATION AND TESTING OF BACTERIUM RESISTANT TO ONE OR MORE ANTIBIOTICS | Nanyang Technological University (SG) | 2024-11-06 | — | — | EP | disclosed |
| CN-118541492-A | Method for identifying bacteria and testing bacteria resistant to one or more antibiotics | 南洋理工大学 | 2024-08-23 | — | — | CN | disclosed |
| WO-2023245172-A1 | METHODS FOR QUANTIFYING LIVE BACTERIA | ANCERA INC. (US) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023128875-A2 | METHOD OF BACTERIAL IDENTIFICATION AND TESTING OF BACTERIUM RESISTANT TO ONE OR MORE ANTIBIOTICS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2023-07-06 | — | — | WO | disclosed |
| WO-2023092715-A1 | ALANINE AGGREGATION-INDUCED EMISSION FLUORESCENT PROBE, AND SYNTHESIS METHOD THEREFOR AND USE THEREOF | 深圳先进技术研究院 | 2023-06-01 | — | — | WO | disclosed |
| CN-116143749-A | Alanine aggregation-induced emission fluorescent probe and synthesis method and application thereof | 深圳先进技术研究院 | 2023-05-23 | — | — | CN | disclosed |
| US-20210325398-A1 | TARGETED SIALIC ACID LABELING COMPOUNDS, METHODS, AND USES THEREOF | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT | 2021-10-21 | — | — | US | disclosed |