Pyridine

Pyridine

SCHEMBL2537121

Cl.NO.c1ccncc1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL8328719 0.96
Pyridine SCHEMBL17101599 0.88
Pyridine SCHEMBL9332905 0.88
Pyridine SCHEMBL8398488 0.88 TSHR (0.90)
Pyridine SCHEMBL8398481 0.88 TSHR (0.90)
Pyridine SCHEMBL8733404 0.88 TSHR (0.90)
Pyridine SCHEMBL3706899 0.88
Pyridine SCHEMBL2810359 0.88
Pyridine SCHEMBL3706898 0.88 TSHR (0.90)
Pyridine SCHEMBL11673636 0.88 TSHR (0.90)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113740470-B Method for judging whether loquat honey is mature or not and application 中国农业科学院蜜蜂研究所 2022-04-19 CN claimed
CN-113740470-A Method for judging whether loquat honey is mature or not and application 中国农业科学院蜜蜂研究所 2021-12-03 CN claimed
CN-106442794-B A kind of method of gas chromatography mass spectrometry separation detection coniferyl alcohol and sinapinic alcohol 安徽农业大学 2018-12-18 CN claimed
CN-106442756-B A kind of analysis method of malt amylase process Linoleic acid metabolin 青岛啤酒股份有限公司 2018-11-27 CN claimed
CN-105548404-B It is a kind of that Huoshan rice dry measure used in former times and the method for huoshan dendrobium candidum kind are differentiated based on metabolism group 安徽农业大学 2017-09-26 CN claimed
CN-106442794-A Method for separating and detecting coniferyl alcohol and sinapyl alcohol through gas chromatography-mass spectrometry (GC-MS) 安徽农业大学 2017-02-22 CN claimed
CN-118020825-A Fresh-keeping storage method for delaying apricot fruit softening based on pulsed strong light synergistic modified atmosphere 郑州轻工业大学 2024-05-14 CN disclosed
CN-117186261-A Exocarpium Citri Grandis homogeneous polysaccharide, and its preparation method and application 广州中医药大学(广州中医药研究院) 2023-12-08 CN disclosed
CN-116284485-A Polygonatum cyrtonema polysaccharide for resisting fatigue and improving immunity as well as preparation method and application thereof 南京中医药大学 2023-06-23 CN disclosed
CN-115406985-A Method for characterizing polysaccharide structure information and method for identifying authenticity or quality of traditional Chinese medicine 南京师范大学 2022-11-29 CN disclosed
CN-113740470-B Method for judging whether loquat honey is mature or not and application 中国农业科学院蜜蜂研究所 2022-04-19 CN disclosed
CN-113740470-A Method for judging whether loquat honey is mature or not and application 中国农业科学院蜜蜂研究所 2021-12-03 CN disclosed
CN-108384821-B Preparation method of oligosaccharide for promoting proliferation of intestinal probiotics 江苏省农业科学院 2021-09-14 CN disclosed
EP-1681280-B1 NOVEL PHENOL DERIVATIVES AND ANTITRYPANOSOMA PREVENTIVE/THERAPEUTIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT ARIGEN PHARMACEUTICALS INC (JP) 2009-03-25 EP disclosed
US-20090054387-A1 Method for preparing 4-[17beta-methoxy-17alpha-methoxymethyl-3-oxestra-4,9-dien-11beta-yl]benzaldehyde (E)-oxime (asoprisnil) BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2009-02-26 US disclosed
EP-2010555-A2 METHOD FOR PREPARING 4-[17BETA -METHOXY-17 -ALPHA METHOXYMETHYL-3-OXOESTRA-4,9-DIEN-11BETA -YL]BENZALDEHYDE (E)-OXIME (ASOPRISNIL) Bayer Schering Pharma Aktiengesellschaft (DE) 2009-01-07 EP disclosed
WO-2007118717-A2 METHOD FOR PREPARING 4-[17β-METHOXY-17α-METHOXYMETHYL-3-OXOESTRA-4,9-DIEN-11β-YL]BENZALDEHYDE (E)-OXIME (ASOPRISNIL) BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-10-25 WO disclosed
US-20070208078-A1 NOVEL PHENOL DERIVATIVES AND ANTITRYPANOSOMA PREVENTIVE/THERAPEUTIC AGENT COMPRISING THE SAME AS ACTIVE INGREDIENT ARIGEN, INC. (JP) 2007-09-06 US disclosed
CN-1882523-A Novel phenol derivative, and anti-trypanosomiasis medicine with the phenol derivative as effective ingredient ARIJI KK (JP) 2006-12-20 CN disclosed
EP-1681280-A1 NOVEL PHENOL DERIVATIVES AND ANTITRYPANOSOMA PREVENTIVE/THERAPEUTIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT aRigen, Inc. (JP) 2006-07-19 EP disclosed