Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.43 |
| ▸ | CYP19A1 known ✓ | P11511 | 1/20 | 0.42 |
| ▸ | HRH3 known ✓ | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.54 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81566 | 0.98 | — | — | |
| SCHEMBL2370829 | 0.96 | TBXAS1 (0.51) | TBXAS1TERTTAAR1HTR1AALOX15 | |
| Iodide SCHEMBL27827657 | 0.96 | TBXAS1 (0.51) | TBXAS1TERTTAAR1HTR1AALOX15 | |
| Bromide SCHEMBL27862059 | 0.96 | TBXAS1 (0.51) | TBXAS1TERTTAAR1HTR1AALOX15 | |
| Fluoride SCHEMBL27922904 | 0.96 | TBXAS1 (0.51) | TBXAS1TERTTAAR1HTR1AALOX15 | |
| Ammonia Solution, Strong SCHEMBL27821905 | 0.96 | TBXAS1 (0.51) | TBXAS1TERTTAAR1HTR1AALOX15 | |
| SCHEMBL28241374 | 0.96 | TBXAS1 (0.51) | TBXAS1TERTTAAR1HTR1AALOX15 | |
| Trimethylammonium SCHEMBL27567321 | 0.94 | TBXAS1 (0.50) | TBXAS1TERTTAAR1HTR1AALOX15 | |
| Hydrochloric Acid SCHEMBL28820175 | 0.94 | TBXAS1 (0.57) | TBXAS1TERTTAAR1HTR1AALOX15 | |
| Bromide SCHEMBL29096133 | 0.94 | TBXAS1 (0.50) | TBXAS1TERTTAAR1HTR1AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651073-A | A method of preparing perfluor butyl iodide | 浙江昊唐实业有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-109503313-A | A kind of method of industrialized production trifluoroiodomethane | 浙江昊唐实业有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-103898802-B | A kind of transparency cellulose film and preparation method thereof | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2015-10-28 | — | — | CN | claimed |
| CN-118085643-A | Dispersion containing nano material and preparation method and application thereof | 中国科学院化学研究所 | 2024-05-28 | — | — | CN | disclosed |
| CN-115260320-B | Use of ionic polysaccharide derivatives as anti-icing coating materials | 中国科学院化学研究所 | 2023-05-05 | — | — | CN | disclosed |
| CN-115260839-B | Use of ionic polysaccharide derivatives as antifog coating materials | 中国科学院化学研究所 | 2023-04-14 | — | — | CN | disclosed |
| CN-115260320-A | Use of ionic polysaccharide derivatives as anti-icing coating materials | 中国科学院化学研究所 | 2022-11-01 | — | — | CN | disclosed |
| CN-115260839-A | Use of ionic polysaccharide derivatives as antifog coating materials | 中国科学院化学研究所 | 2022-11-01 | — | — | CN | disclosed |
| CN-110863106-B | Method for extracting copper ions by ionic liquid through aqueous two-phase extraction | 江南大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-109180475-B | Method for synthesizing diisooctyl terephthalate through rapid esterification without alkali washing and water washing | 华侨大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-108951228-B | Dyeing process of wool fabric | 江阴兴吴呢绒科技有限公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-109772453-A | Ionic liquid functionalized PVA catalytic composite membrane and preparation method thereof | 南京工业大学 | 2019-05-21 | — | — | CN | disclosed |
| CN-109651073-A | A method of preparing perfluor butyl iodide | 浙江昊唐实业有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-109503313-A | A kind of method of industrialized production trifluoroiodomethane | 浙江昊唐实业有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-104557905-B | A kind of preparation method of Tiotropium Bromide intermediate | 天津金耀集团有限公司 | 2018-02-23 | — | — | CN | disclosed |
| CN-107413379-A | For alkyl carbonate and the catalyst and preparation method of aryl alcohol transesterification reaction | 濮阳市宏源石油化工有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-103898802-B | A kind of transparency cellulose film and preparation method thereof | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2015-10-28 | — | — | CN | disclosed |
| CN-101003457-B | Method for preparing tri - isopropyl benzene by using catalyst of ion liquid | UNIV BEIJING CHEMICAL | 2010-05-12 | — | — | CN | disclosed |
| CN-101219995-A | Ion liquid based on heteropoly acid and synthesis thereof | UNIV EAST CHINA SCIENCE & TECH (CN) | 2008-07-16 | — | — | CN | disclosed |
| CN-101003457-A | Method for preparing tri - isopropyl benzene by using catalyst of ion liquid | UNIV BEIJING CHEMICAL (CN) | 2007-07-25 | — | — | CN | disclosed |