Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.41 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.39 |
| ▸ | HRH3 known ✓ | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.50 |
| ▸ | APEX1 | P27695 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3634436 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL22283007 | 0.96 | DNM1 (0.53) | DNM1APEX1NPSR1CYP3A4SLC5A7 | |
| Hydrochloric Acid SCHEMBL22282998 | 0.96 | DNM1 (0.53) | DNM1APEX1NPSR1CYP3A4SLC5A7 | |
| Hydrochloric Acid SCHEMBL28087292 | 0.96 | — | — | |
| Ammonia Solution, Strong SCHEMBL27791732 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL28300489 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL28269780 | 0.93 | DNM1 (0.45) | DNM1APEX1NPSR1CYP3A4SLC5A7 | |
| Hydrochloric Acid SCHEMBL20769541 | 0.93 | DNM1 (0.56) | DNM1APEX1NPSR1CYP3A4SLC5A7 | |
| Hydrochloric Acid SCHEMBL196186 | 0.93 | — | — | |
| Water SCHEMBL1397159 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565898-A | Three-proofing finishing agent as well as preparation method and application thereof | 苏州联胜化学有限公司 | 2017-04-19 | — | — | CN | claimed |
| CN-108698029-A | High charge density metal silicophosphate molecular sieve SAPO-79 | 环球油品公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-106150436-B | Hydrogen sulfide eliminates suppressing method in a kind of oil well production process | 中国石油化工股份有限公司 | 2018-08-17 | — | — | CN | disclosed |
| CN-108096173-A | Mild amino acid shampoo of a kind of green and preparation method thereof | 广州蜜妆生物科技有限公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-104220042-B | Foaming formulations comprising silicone-based polyurethanes | 金伯利-克拉克环球有限公司 | 2018-04-24 | — | — | CN | disclosed |
| CN-105837096-B | A kind of concrete production technology | 北京奥润开元环保科技研究院有限公司 | 2018-04-10 | — | — | CN | disclosed |
| CN-107789223-A | A kind of color protection highlights shampoo composite | 拉芳家化股份有限公司 | 2018-03-13 | — | — | CN | disclosed |
| CN-105776973-B | A kind of low-cost concrete and its production technology comprising slag and road-surface milling material | 北京奥润开元环保科技研究院有限公司 | 2017-07-21 | — | — | CN | disclosed |
| CN-105776974-B | Low-cost concrete and its production technology | 北京奥润开元环保科技研究院有限公司 | 2017-07-21 | — | — | CN | disclosed |
| CN-105801029-B | A kind of concrete new production process | 北京奥润开元环保科技研究院有限公司 | 2017-06-27 | — | — | CN | disclosed |
| CN-102858940-B | Delivery particles | 宝洁公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-104072394-B | The manufacture method of nitrile compound | 住友化学株式会社 | 2017-04-05 | — | — | CN | disclosed |
| CN-104244921-B | Comprise the effervescent preparations of silicone polyester | 金伯利-克拉克环球有限公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-104220043-B | Foaming formulations and cleaning products comprising silicone polyesters | 金伯利-克拉克环球有限公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-103589530-B | Delivery of particles | 宝洁公司 | 2016-08-24 | — | — | CN | disclosed |