Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK known ✓ | P06239 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28183297 | 0.98 | NOD1 (0.51) | NOD1GRIK1GRIK2GPR84FFAR1 | |
| Hydrochloric Acid SCHEMBL11275282 | 0.97 | GRIK1 (0.46) | NOD1GRIK1GRIK2GPR84FFAR1 | |
| Hydrochloric Acid SCHEMBL4800870 | 0.97 | GRIK1 (0.46) | NOD1GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL129873 | 0.95 | GRIK1 (0.47) | NOD1GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL10878349 | 0.95 | GRIK1 (0.47) | NOD1GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL608197 | 0.95 | GRIK1 (0.47) | NOD1GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL1830577 | 0.95 | GRIK1 (0.47) | NOD1GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL11256357 | 0.95 | GRIK1 (0.47) | NOD1GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL8144409 | 0.94 | GRIK1 (0.46) | NOD1GRIK1GRIK2GPR84FFAR1 | |
| SCHEMBL1866979 | 0.94 | GRIK1 (0.46) | NOD1GRIK1GRIK2GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114987967-A | Degradable garbage bag produced by using waste plastics and preparation method thereof | 江苏洁雅家居用品有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-107675228-B | A kind of colouring method of power distribution cabinet radiating shell | 中泽电气科技有限公司 | 2019-04-23 | — | — | CN | claimed |
| CN-108839186-A | A kind of ramulus mori knitting mildew-proof treatment method | 阜南县金威工艺品有限公司 | 2018-11-20 | — | — | CN | claimed |
| CN-107828229-A | A kind of waste plastic recovery method for lifting thermal change type temperature | 界首市锦丰塑业有限公司 | 2018-03-23 | — | — | CN | claimed |
| CN-107522916-A | A kind of preparation method of the rubber seal of high temperature oxidation resisting | 宁国市宁和密封件厂 | 2017-12-29 | — | — | CN | claimed |
| CN-107522948-A | A kind of woven bag | 盐城华和再生物资有限公司 | 2017-12-29 | — | — | CN | claimed |
| CN-114987967-A | Degradable garbage bag produced by using waste plastics and preparation method thereof | 江苏洁雅家居用品有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-107675228-B | A kind of colouring method of power distribution cabinet radiating shell | 中泽电气科技有限公司 | 2019-04-23 | — | — | CN | disclosed |
| CN-108839186-A | A kind of ramulus mori knitting mildew-proof treatment method | 阜南县金威工艺品有限公司 | 2018-11-20 | — | — | CN | disclosed |
| CN-108748556-A | A kind of method of windmill palm vine material dyeing | 安徽戴家工艺有限公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-107675228-A | A kind of colouring method of power distribution cabinet radiating shell | 安徽中泽电气科技有限公司 | 2018-02-09 | — | — | CN | disclosed |
| CN-107522948-A | A kind of woven bag | 盐城华和再生物资有限公司 | 2017-12-29 | — | — | CN | disclosed |
| CN-107326729-A | A kind of preparation method of environment-friendly waterproof corrugated case | 合肥龙发包装有限公司 | 2017-11-07 | — | — | CN | disclosed |