Hydrochloric Acid

Hydrochloric Acid

SCHEMBL287803

Cl.NNc1cccc(Cl)c1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA known ✓ P10253 4/20 0.50
HTR3E known ✓ A5X5Y0 2/20 0.48
HTR3B known ✓ O95264 2/20 0.48
HTR3A known ✓ P46098 2/20 0.48
HTR3D known ✓ Q70Z44 2/20 0.48
HTR3C known ✓ Q8WXA8 2/20 0.48
PTGS2 known ✓ P35354 1/20 0.46
IDO1 P14902 2/20 0.55
ALDH1A1 P00352 3/20 0.52
MAPT P10636 5/20 0.52
LMNA P02545 4/20 0.52
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
HTT P42858 2/20 0.52
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31620030 1.00 IDO1 (0.55) IDO1ALDH1A1MAPTLMNAKMT2A
SCHEMBL7823 0.98
Water SCHEMBL17375142 0.95 IDO1 (0.55) IDO1ALDH1A1MAPTLMNAKMT2A
Bromide SCHEMBL20984750 0.95 IDO1 (0.55) IDO1ALDH1A1MAPTLMNAKMT2A
Hydrochloric Acid SCHEMBL6770230 0.93 IDO1 (0.53) IDO1ALDH1A1MAPTLMNAKMT2A
Cyanide SCHEMBL17767363 0.91 IDO1 (0.52) IDO1ALDH1A1MAPTLMNAKMT2A
Sulfuric Acid SCHEMBL11363114 0.87 MEN1 (0.55) IDO1ALDH1A1MAPTLMNAKMT2A
Sulfuric Acid SCHEMBL11243238 0.87 MEN1 (0.55) IDO1ALDH1A1MAPTLMNAKMT2A
Phosphoric Acid SCHEMBL20984059 0.86 MAPT (0.53) IDO1ALDH1A1MAPTLMNAKMT2A
Oxalic Acid SCHEMBL20984322 0.86 MAPT (0.58) IDO1ALDH1A1MAPTLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 476 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025020685-A1 PEROVSKITE THIN FILM LAYER AND PREPARATION METHOD THEREFOR, AND PEROVSKITE SILICON STACKED SOLAR CELL AND PREPARATION METHOD THEREFOR 通威太阳能(成都)有限公司 2025-01-30 WO claimed
CN-116887609-A Perovskite thin film layer and preparation method thereof, perovskite silicon laminated solar cell and preparation method thereof 通威太阳能(成都)有限公司 2023-10-13 CN claimed
US-11040938-B2 Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) 2021-06-22 US claimed
CN-107663161-B Continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt 上海惠和化德生物科技有限公司 2020-04-10 CN claimed
US-20190152896-A1 Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) 2019-05-23 US claimed
CN-106749288-B N- (substituted-phenyl) Bi Zuo Bing fraxinellones analog derivative, preparation method and application 郑州大学 2018-07-10 CN claimed
CN-106749288-A N (substituted benzene) base Bi Zuo Ji fraxinellones analog derivative, its preparation method and application 郑州大学 2017-05-31 CN claimed
CN-105198771-A Method for preparing 3-chlorophenylhydrazine hydrochloride TIANJIN CHEM REAGENT RES INST 2015-12-30 CN claimed
CN-104109104-A Preparation method of 3-chlorophenylhydrazine hydrochloride TIANJIN CHEM REAGENT RES INST 2014-10-22 CN claimed
EP-0918052-B1 Improved polymeric mdi color BAYER AG (US) 2003-05-28 EP claimed
US-5942151-A PREVENTING THE DISCOLORATION OF PRODUCING POLYMETHYLENEPOLYPHENYLENE POLYISOCYANATE BY ADDING AN ADDITIVE HYDRAZINE OR A HYDRAZINE DERIVATIVE BAYER CORPORATION (US) 1999-08-24 US claimed
EP-0918052-A1 Improved polymeric mdi color Bayer Corporation (US) 1999-05-26 EP claimed
US-20260041683-A1 Compounds with Anti-Acinetobacter Baumannii Activity UNIV KENTUCKY RES FOUND (US) 2026-02-12 US disclosed
CN-120060869-A Electrocatalytic synthesis method of aryl sulfone compound 平顶山学院 2025-05-30 CN disclosed
CN-120077042-A 3A,4,5, 6-tetrahydro-1H-pyrazolo [3,4-C ] pyridin-7 (7 AH) -one derivatives as factor XIIa inhibitors 卡尔维斯塔制药有限公司 2025-05-30 CN disclosed
CN-119751423-A Pyrimidine-containing aryl pyrazole oxime ether compound as well as preparation method and application thereof 河南大学 2025-04-04 CN disclosed
US-3948929-A ANTIINFLAMMATORY, ANTIPYRETIC MILES LABORATORIES, INC. (US) 1976-04-06 US disclosed
US-3948930-A ANTIINFLAMMATORY, ANTIPYRETIC MILES LABORATORIES, INC. (US) 1976-04-06 US disclosed
US-3948932-A ANTIINFLAMMATORY, ANTIPYRETIC MILES LABORATORIES, INC. (US) 1976-04-06 US disclosed
US-3936444-A FROM A LACTIM-ETHER AND AN ARYL OR HETEROARYL HYDRAZINE, ACID CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11040938-B2 Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts HPD, TYR, PDK2 GAA 237/4885HTR3E 2484/4885HTR3B 2357/4885
US-20260041683-A1 Compounds with Anti-Acinetobacter Baumannii Activity ABCC1, SLC11A2, ANTXR2 GAA 1039/4885HTR3E 3356/4885HTR3B 4336/4885
US-20190152896-A1 Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts HPD, TYR, PDK2 GAA 237/4885HTR3E 2484/4885HTR3B 2357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.