Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 known ✓ | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B known ✓ | P08514 | 1/20 | 0.31 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 7/20 | 0.32 |
| ▸ | NPY1R | P25929 | 4/20 | 0.32 |
| ▸ | NPY2R | P49146 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GGT1 | P19440 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23296534 | 0.99 | C3AR1 (0.35) | C3AR1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL2485111 | 0.99 | C3AR1 (0.35) | C3AR1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL9924206 | 0.86 | C3AR1 (0.34) | C3AR1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL2483025 | 0.86 | C3AR1 (0.34) | C3AR1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL11727564 | 0.84 | USP2 (0.37) | C3AR1NPY4RNPY1RNPY2RNPY5R | |
| Hydrochloric Acid SCHEMBL27645702 | 0.83 | NPY4R (0.36) | C3AR1NPY4RNPY1RNPY2RNPY5R | |
| Hydrochloric Acid SCHEMBL7111708 | 0.83 | GPR84 (0.42) | — | |
| Hydrochloric Acid SCHEMBL27456313 | 0.83 | GPR84 (0.42) | — | |
| Hydrochloric Acid SCHEMBL6546097 | 0.83 | GPR84 (0.42) | — | |
| Hydrochloric Acid SCHEMBL27454617 | 0.83 | GPR84 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115969726-B | Multi-effect composition, shampoo and preparation method thereof | 广州市芙缇化妆品有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-119745741-A | Non-irritant temperature-sensitive mud film and preparation method thereof | 南风化工(运城)集团有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119656066-A | Mussel special-moistening essence and preparation method thereof | 广州莱度技术开发有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-118845536-A | Acne-removing frosted shower gel and preparation method thereof | 广州汇创化妆品有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118750414-A | Volcanic mud oil-control face-cleaning freeze-dried cosmetic and preparation method and application thereof | 莫娅(上海)品牌管理有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-116725892-B | Composition capable of regulating skin flora balance, controlling oil and preserving moisture and application thereof | 广州玥颜化妆品有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-116999350-A | Amino acid facial cleanser and preparation method thereof | 彭氏(惠州)实业发展有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116725892-A | Composition capable of regulating skin flora balance, controlling oil and preserving moisture and application thereof | 广州玥颜化妆品有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-115887242-B | Shaking-free foam hair wax and preparation method thereof | 中山市澳臣精细化工实业有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-115969726-A | Multi-effect composition, shampoo and preparation method thereof | 广州市芙缇化妆品有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115887242-A | Shaking-free foam foaming wax and preparation method thereof | 中山市澳臣精细化工实业有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115607479-A | Moisturizing composition and moisturizing liquid for skin | 上海臻臣化妆品有限公司 | 2023-01-17 | — | — | CN | claimed |
| CN-115252533-A | Moisturizing and repairing composition and preparation method and application thereof | 广州瑞誉化工科技有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-114796014-A | Efficient acne-removing anti-allergy face-cleaning mousse and preparation method thereof | 顾远玥 | 2022-07-29 | — | — | CN | claimed |
| CN-122031341-A | Anal Zhou Huli liquid containing herbaceous plants and hyaluronic acid and preparation method thereof | 山东焦点福瑞达生物股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-116650361-B | Skin moisturizing composition and application thereof as well as daily chemical product | 上海友仁生物科技有限公司 | 2026-03-17 | — | — | CN | disclosed |
| CN-120294210-A | Method for detecting related substances of dihydroxypropyl arginine hydrochloride | 苏州博研医药科技有限公司 | 2025-07-11 | — | — | CN | disclosed |
| CN-115192482-A | Removable mask dry sheet taking black mud as main matrix and preparation method and application thereof | 山西焦煤运城盐化集团有限责任公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-114796014-A | Efficient acne-removing anti-allergy face-cleaning mousse and preparation method thereof | 顾远玥 | 2022-07-29 | — | — | CN | disclosed |
| CN-114796014-A | Efficient acne-removing anti-allergy face-cleaning mousse and preparation method thereof | 顾远玥 | 2022-07-29 | — | — | CN | disclosed |