Surotomycin

Surotomycin

SCHEMBL29384312

CCCCCc1ccc(/C(C)=C/C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@H](CC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]2C(=O)NCC(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@H](CO)C(=O)N[C@@H]([C@H](C)CC(=O)O)C(=O)N[C@@H](CC(=O)c3ccccc3N)C(=O)O[C@@H]2C)cc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 1/20 0.82
▸ DRD1 P21728 1/20 0.82
▸ PTGS1 P23219 1/20 0.82
▸ PDE4A P27815 1/20 0.82
▸ EPHA2 P29317 3/20 0.38
▸ IL23R Q5VWK5 4/20 0.37
▸ KCNMA1 Q12791 1/20 0.37
▸ KCNMB4 Q86W47 1/20 0.37
▸ NECTIN4 Q96NY8 3/20 0.36
▸ KEAP1 Q14145 1/20 0.36
▸ F2 P00734 1/20 0.36
▸ F11 P03951 1/20 0.35
▸ KRAS P01116 1/20 0.35
▸ ITGB3 P05106 1/20 0.35
▸ ITGB1 P05556 1/20 0.35
▸ ITGAV P06756 1/20 0.35
▸ ITGA5 P08648 1/20 0.35
▸ ITGB6 P18564 1/20 0.35
▸ ITGB8 P26012 1/20 0.35
▸ MDM2 Q00987 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Surotomycin SCHEMBL13246889 1.00 CTSL (0.82) CTSLDRD1PTGS1PDE4AEPHA2
Surotomycin SCHEMBL15177344 1.00 CTSL (0.82) CTSLDRD1PTGS1PDE4AEPHA2
Surotomycin SCHEMBL17284900 1.00 CTSL (0.82) CTSLDRD1PTGS1PDE4AEPHA2
Surotomycin SCHEMBL13246848 1.00 CTSL (0.82) CTSLDRD1PTGS1PDE4AEPHA2
Surotomycin SCHEMBL13267854 1.00 CTSL (0.82) CTSLDRD1PTGS1PDE4AEPHA2
Surotomycin SCHEMBL29497451 1.00 CTSL (0.82) CTSLDRD1PTGS1PDE4AEPHA2
SCHEMBL13246857 1.00 CTSL (0.83) CTSLDRD1PTGS1PDE4AEPHA2
SCHEMBL13246850 0.99 CTSL (0.81) CTSLDRD1PTGS1PDE4AEPHA2
SCHEMBL25541987 0.96 CTSL (0.75) CTSLDRD1PTGS1PDE4AEPHA2
SCHEMBL25541971 0.96 CTSL (0.75) CTSLDRD1PTGS1PDE4AEPHA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260027140-A1 COMPOSITIONS AND METHODS FOR TREATING AND AMELIORATING RESPIRATORY CONDITIONS AND INFLAMMATION OF MUCOSA ATOPIC MEDICAL INC (US) 2026-01-29 — — US claimed
WO-2025059113-A1 TREATMENTS FOR ENHANCING IMMUNE RESPONSE TO CLOSTRIDIOIDES DIFFICILE INFECTIONS THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2025-03-20 — — WO claimed
WO-2022040799-A1 ANTIMICROBIAL COMPOSITION GP TECH INOVASYON TEKNOLOJI VE ARASTIRMA A.S (TR) 2022-03-03 — — WO claimed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
WO-2026090542-A1 BETA-AMINO-ESTER AND BETA-THIOL-ESTER CONTAINING POLYMERS FOR DRUG DELIVERY AND PHARMACEUTICAL USES EMORY UNIVERSITY (US) 2026-04-30 — — WO disclosed
US-12601740-B2 Method and kit for identifying antimicrobial agents and effective concentrations thereof COBIO DIAGNOSTICS INC. (US) 2026-04-14 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
US-20260085341-A1 Using Multiple Heteroresistance to Guide Combination Antimicrobial Regimens UNIV EMORY (US) 2026-03-26 — — US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
US-20260060822-A1 BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF UNIV WAKE FOREST HEALTH SCIENCES (US) 2026-03-05 — — US disclosed
WO-2022112595-A1 NOVEL REPLICATION DEFICIENT INFLUENZA A VIRUS INDUCING HIGH LEVELS OF TYPE I INTERFERON BLUESKY IMMUNOTHERAPIES GMBH (AT) 2022-06-02 — — WO disclosed
US-20220143040-A1 ANTIVIRAL TREATMENT CEBINA GmbH (AT) 2022-05-12 — — US disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
EP-3966223-A1 PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
US-11273163-B2 Antiviral treatment CEBINA GmbH (AT) 2022-03-15 — — US disclosed
WO-2022040799-A1 ANTIMICROBIAL COMPOSITION GP TECH INOVASYON TEKNOLOJI VE ARASTIRMA A.S (TR) 2022-03-03 — — WO disclosed
EP-3960729-A1 COMPOUNDS AND METHODS OF TREATING INFECTIONS Neoculi Pty Ltd (AU) 2022-03-02 — — EP disclosed
CN-114126619-A Compounds for the synthesis of peptidomimetics 范因斯坦医学研究院 2022-03-01 — — CN disclosed
US-11246312-B2 Antimicrobial compositions and methods of using same CROWPIERCE TECHNOLOGIES, LLC (US) 2022-02-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260027140-A1 COMPOSITIONS AND METHODS FOR TREATING AND AMELIORATING RESPIRATORY CONDITIONS AND INFLAMMATION OF MUCOSA IL1B, IL5, SERPINB1 CTSL 56/4885DRD1 4874/4885PTGS1 1118/4885
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS CTSL 1003/4885DRD1 302/4885PTGS1 3055/4885
US-20260085341-A1 Using Multiple Heteroresistance to Guide Combination Antimicrobial Regimens Q6ZSR9, AMPD2, AMPD1 CTSL 126/4885DRD1 936/4885PTGS1 4860/4885
US-12601740-B2 Method and kit for identifying antimicrobial agents and effective concentrations thereof MYD88, TNFSF11, TNF CTSL 141/4885DRD1 2403/4885PTGS1 4363/4885
US-20220143040-A1 ANTIVIRAL TREATMENT ACE, SARS1, TRIM25 CTSL 83/4885DRD1 747/4885PTGS1 2167/4885
US-20260060822-A1 BIOENGINEERED SCAFFOLDS FOR VASCULAR GRAFTS AND METHODS OF USE THEREOF PFKP, PBK, MYLK CTSL 1755/4885DRD1 4725/4885PTGS1 1138/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 CTSL 562/4885DRD1 3675/4885PTGS1 3510/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 CTSL 790/4885DRD1 3490/4885PTGS1 3935/4885
US-11273163-B2 Antiviral treatment ACE, SARS1, TRIM25 CTSL 90/4885DRD1 635/4885PTGS1 2614/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT CTSL 886/4885DRD1 2192/4885PTGS1 3489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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