Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.37 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1628529 | 0.98 | CA1 (0.38) | CA1CA2MAPTTP53LMNA | |
| Iodide SCHEMBL28977654 | 0.97 | CA1 (0.37) | CA1CA2MAPTTP53LMNA | |
| SCHEMBL28568820 | 0.92 | MAPT (0.37) | CA1CA2MAPTTP53LMNA | |
| SCHEMBL19362304 | 0.86 | ALDH1A1 (0.44) | CA1CA2MAPTTP53LMNA | |
| Hydrochloric Acid SCHEMBL30286340 | 0.84 | MAPT (0.36) | CA1CA2MAPTTP53LMNA | |
| SCHEMBL15803245 | 0.84 | HRH3 (0.34) | CA2MAPTTP53LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL28707646 | 0.84 | CA1 (0.37) | CA1CA2MAPTTP53LMNA | |
| SCHEMBL28014802 | 0.82 | CA1 (0.38) | CA1CA2MAPTTP53LMNA | |
| Hydrochloric Acid SCHEMBL28447947 | 0.82 | CA1 (0.38) | CA1CA2MAPTTP53LMNA | |
| Bromide SCHEMBL28376642 | 0.81 | CA1 (0.37) | CA1CA2MAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119100665-A | Composite cement mortar resistant to chloride ion corrosion and preparation method thereof | 青岛理工大学 | 2024-12-10 | — | — | CN | claimed |
| CN-118388718-A | MXene-TiO2Ag double-layer hydrogel and preparation and application thereof | 西北师范大学 | 2024-07-26 | — | — | CN | claimed |
| CN-116613398-A | Positive electrode lithium supplementing composite material, preparation method thereof and lithium ion battery comprising positive electrode lithium supplementing composite material | 合肥国轩高科动力能源有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-113567528-B | Composite material modified nicotine sensor, preparation method thereof and method for detecting nicotine content in tobacco leaves by adopting composite material modified nicotine sensor | 同济大学 | 2023-05-09 | — | — | CN | claimed |
| CN-115867586-A | Electrochemically debondable adhesive compositions | 汉高股份有限及两合公司 | 2023-03-28 | — | — | CN | claimed |
| CN-114044862-B | Preparation method of chitin brush-shaped conductive elastomer material and prepared material | 安徽农业大学 | 2022-08-19 | — | — | CN | claimed |
| CN-113567528-A | Composite material modified nicotine sensor, preparation method thereof and method for detecting nicotine content in tobacco leaves by using composite material modified nicotine sensor | 同济大学 | 2021-10-29 | — | — | CN | claimed |
| CN-108007992-B | Detect the preparation method of the poly ion liquid@3D nanogold cluster modified electrode of hemoglobin | 辽宁师范大学 | 2019-08-09 | — | — | CN | claimed |
| CN-119100665-A | Composite cement mortar resistant to chloride ion corrosion and preparation method thereof | 青岛理工大学 | 2024-12-10 | — | — | CN | disclosed |
| CN-119100665-A | Composite cement mortar resistant to chloride ion corrosion and preparation method thereof | 青岛理工大学 | 2024-12-10 | — | — | CN | disclosed |
| CN-118388718-A | MXene-TiO2Ag double-layer hydrogel and preparation and application thereof | 西北师范大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-117467226-B | Composition, sensing film, sensor, preparation method and application | 上海拜安传感技术有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117467226-A | Composition, sensing film, sensor, preparation method and application | 上海拜安传感技术有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-116613398-A | Positive electrode lithium supplementing composite material, preparation method thereof and lithium ion battery comprising positive electrode lithium supplementing composite material | 合肥国轩高科动力能源有限公司 | 2023-08-18 | — | — | CN | disclosed |
| US-20140027938-A1 | PROCESS FOR ELECTROSPINNING CHITIN FIBERS FROM CHITINOUS BIOMASS SOLUTION AND FIBERS AND ARTICLES PRODUCED THEREBY | BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2014-01-30 | — | — | US | disclosed |
| CN-103122187-A | Ionic liquid modified marine antifouling paint | LANZHOU CHEM PHYS INST | 2013-05-29 | — | — | CN | disclosed |
| CN-103122047-A | Preparation method for antifouling paint matrix resin containing ionic liquid perssads | LANZHOU CHEM PHYS INST | 2013-05-29 | — | — | CN | disclosed |
| US-7732099-B2 | Composite polymer electrolyte composition | TREKION CO., LTD. (JP) | 2010-06-08 | — | — | US | disclosed |
| US-20060057465-A1 | Composite polymer electrolyte composition | TREKION CO., LTD. (JP) | 2006-03-16 | — | — | US | disclosed |
| EP-1612809-A1 | COMPOSITE POLYMER ELECTROLYTE COMPOSITION | Trekion Co. Ltd. (JP) | 2006-01-04 | — | — | EP | disclosed |