Taurine

Taurine

SCHEMBL29403235

NCCS(=O)(=O)[O-].NCCS(=O)(=O)[O-].NCCS(=O)(=O)[O-].[Na+].[Na+].[Na+]

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Taurine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
LMNA P02545 2/20 0.68
TSHR P16473 2/20 0.68
GMNN O75496 1/20 0.68
TP53 P04637 1/20 0.68
MAPK1 P28482 1/20 0.68
THPO P40225 1/20 0.68
HBB P68871 1/20 0.68
PMP22 Q01453 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
KDM4E B2RXH2 1/20 0.50
MAPT P10636 1/20 0.50
ALOX15 P16050 1/20 0.50
SLC6A6 P31641 1/20 0.45
CYP2C19 P33261 1/20 0.45
BLM P54132 1/20 0.45
ENPEP Q07075 2/20 0.42
HPGD P15428 1/20 0.38
BBOX1 O75936 3/20 0.36
APP P05067 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Taurine SCHEMBL29400164 1.00 ALDH1A1 (0.68) ALDH1A1LMNATSHRGMNNTP53
Taurine SCHEMBL923630 1.00
Taurine SCHEMBL10626131 0.93 LMNA (0.60) ALDH1A1LMNATSHRGMNNTP53
Taurine SCHEMBL688315 0.93
Taurine SCHEMBL29475753 0.93 LMNA (0.60) ALDH1A1LMNATSHRGMNNTP53
Taurine SCHEMBL1100955 0.93
Taurine SCHEMBL2288742 0.93 LMNA (0.60) ALDH1A1LMNATSHRGMNNTP53
Taurine SCHEMBL7107906 0.93 LMNA (0.60) ALDH1A1LMNATSHRGMNNTP53
Taurine SCHEMBL10952592 0.93
Taurine SCHEMBL30097994 0.93 LMNA (0.60) ALDH1A1LMNATSHRGMNNTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11891355-B2 Method for preparing taurine and method for recovering mother liquor thereof ZHEJIANG NHU COMPANY LTD. (CN) 2024-02-06 US claimed
US-11845714-B2 Process for producing taurine VITAWORKS IP, LLC (US) 2023-12-19 US claimed
WO-2026087586-A1 METHOD FOR THE CONTINUOUS MANUFACTURE OF TAURINE ARXADA AG (CH) 2026-04-30 WO disclosed
US-20250051271-A1 METHOD FOR PREPARING TAURINE, METHYLTAURATE AND METHYLTAURINE SIMULTANEOUSLY QIANJIANG YONGAN PHARMACEUTICAL CO., LTD. (CN) 2025-02-13 US disclosed
EP-4506333-A1 METHOD FOR PREPARING TAURINE, METHYLTAURATE AND METHYLTAURINE SIMULTANEOUSLY Qiangjiang Yongan Pharmaceutical Co., Ltd. (CN) 2025-02-12 EP disclosed
US-20240092732-A1 PROCESS FOR PRODUCING TAURINE LIBRE HOLDINGS INC. 2024-03-21 US disclosed
US-11891355-B2 Method for preparing taurine and method for recovering mother liquor thereof ZHEJIANG NHU COMPANY LTD. (CN) 2024-02-06 US disclosed
US-11851395-B2 Process for producing alkali taurinate VITAWORKS IP, LLC (US) 2023-12-26 US disclosed
US-11845714-B2 Process for producing taurine VITAWORKS IP, LLC (US) 2023-12-19 US disclosed
EP-3786153-B1 METHOD AND SYSTEM FOR REMOVING IMPURITIES OUT OF TAURINE MOTHER LIQUOR AND TAURINE MOTHER LIQUOR RECOVERY QIANGJIANG YONGAN PHARMACEUTICAL CO LTD (CN) 2023-07-19 EP disclosed
US-20230192603-A1 PROCESS FOR PRODUCING ALKALI TAURINATE LIBRE HOLDINGS INC. 2023-06-22 US disclosed
US-20220135519-A1 Cyclic Process for Producing Taurine from Monoethanolamine LIBRE HOLDINGS INC. 2022-05-05 US disclosed
CN-111116430-B Preparation method of sodium taurate 万华化学集团股份有限公司 2022-04-22 CN disclosed
EP-3808734-B1 THE METHOD AND PRODUCTION SYSTEM FOR FULLY RECOVERING AND TREATING TAURINE MOTHER LIQUOR QIANGJIANG YONGAN PHARMACEUTICAL CO LTD (CN) 2022-03-30 EP disclosed
WO-2022055782-A1 CYCLIC PROCESS FOR PRODUCING TAURINE FROM MONOETHANOLAMINE VITAWORKS IP, LLC (US) 2022-03-17 WO disclosed
WO-2022055780-A1 CYCLIC PROCESS FOR PRODUCING TAURINE FROM MONOETHANOLAMINE VITAWORKS IP, LLC (US) 2022-03-17 WO disclosed
WO-2022055781-A1 CYCLIC PROCESS FOR PRODUCING TAURINE FROM MONOETHANOLAMINE VITAWORKS IP, LLC (US) 2022-03-17 WO disclosed
US-20220073453-A1 Cyclic Process for Producing Taurine from Monoethanolamine LIBRE HOLDINGS INC. 2022-03-10 US disclosed
US-20220073455-A1 Cyclic Process for Producing Taurine from Monoethanolamine LIBRE HOLDINGS INC. 2022-03-10 US disclosed
US-11254639-B1 Cyclic process for producing taurine from monoethanolamine VITAWORKS IP, LLC (US) 2022-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240092732-A1 PROCESS FOR PRODUCING TAURINE SLC6A6, OSGEP, ABAT ALDH1A1 591/4885LMNA 4220/4885TSHR 3692/4885
US-20220135519-A1 Cyclic Process for Producing Taurine from Monoethanolamine SRM, SMS, PHOSPHO1 ALDH1A1 2265/4885LMNA 3371/4885TSHR 4592/4885
US-11254639-B1 Cyclic process for producing taurine from monoethanolamine SRM, PHOSPHO1, SMS ALDH1A1 2628/4885LMNA 3603/4885TSHR 4437/4885
US-20220073455-A1 Cyclic Process for Producing Taurine from Monoethanolamine SRM, PHOSPHO1, SMS ALDH1A1 2628/4885LMNA 3603/4885TSHR 4437/4885
US-11845714-B2 Process for producing taurine OAT, CA3, MAPT ALDH1A1 1348/4885LMNA 3589/4885TSHR 3774/4885
US-11851395-B2 Process for producing alkali taurinate OAT, CA3, MAPT ALDH1A1 2181/4885LMNA 3170/4885TSHR 4139/4885
US-20230192603-A1 PROCESS FOR PRODUCING ALKALI TAURINATE OAT, CA3, MAPT ALDH1A1 2181/4885LMNA 3170/4885TSHR 4139/4885
US-20220073453-A1 Cyclic Process for Producing Taurine from Monoethanolamine SLC6A6, SMS, SRM ALDH1A1 2976/4885LMNA 1557/4885TSHR 3701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.