Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377109 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL3991927 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL11630886 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL1493263 | 0.78 | ALOX15 (0.36) | — | |
| Hydrochloric Acid SCHEMBL2385982 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL10722495 | 0.77 | MGAM (0.41) | — | |
| SCHEMBL3994671 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL8864784 | 0.75 | KDM4E (0.33) | — | |
| Hydrochloric Acid SCHEMBL989808 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL5305458 | 0.74 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118908874-A | PAD4 inhibitor, preparation method thereof and application thereof in preparation of anti-pulmonary fibrosis drugs | 首都医科大学 | 2024-11-08 | — | — | CN | claimed |
| CN-115141119-A | Ornithine derivative, preparation method thereof, gadobenate dimeglumine-ornithine complex, preparation and application | 首都医科大学 | 2022-10-04 | — | — | CN | claimed |
| WO-2025034569-A9 | STING INHIBITORS AND METHODS OF USING THEREOF | UNIVERSITY OF MASSACHUSETTS (US) | 2025-05-22 | — | — | WO | disclosed |
| CN-119775261-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2025-04-08 | — | — | CN | disclosed |
| WO-2025034569-A2 | STING INHIBITORS AND METHODS OF USING THEREOF | UNIVERSITY OF MASSACHUSETTS (US) | 2025-02-13 | — | — | WO | disclosed |
| CN-115427404-B | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118908874-A | PAD4 inhibitor, preparation method thereof and application thereof in preparation of anti-pulmonary fibrosis drugs | 首都医科大学 | 2024-11-08 | — | — | CN | disclosed |
| CN-118681025-A | Hydrotalcite material loaded with PAD4 inhibitor and preparation method and application thereof | 首都医科大学 | 2024-09-24 | — | — | CN | disclosed |
| CN-118059066-A | Ferric oxide-chitosan-PAD 4 inhibitor nano-drug and preparation method and application thereof | 首都医科大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-115141119-B | Ornithine derivative and preparation method thereof, gadobenate dimeglumine-ornithine complex, and preparation and application thereof | 首都医科大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-117883425-A | PAD4 inhibitor and application of nano-preparation thereof in preparation of ischemic cerebral apoplexy drugs | 首都医科大学 | 2024-04-16 | — | — | CN | disclosed |
| US-4946843-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-08-07 | — | — | US | disclosed |
| EP-0281254-B1 | ANTIARRYTHMIC AGENTS | Pfizer Limited (GB) | 1990-01-17 | — | — | EP | disclosed |
| EP-0307014-A1 | Anti-allergic 2-(heterocyclyl alkyl) imidazo pyridines and 2-(heterocyclyl alkyl) purines | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-03-15 | — | — | EP | disclosed |
| EP-0281254-A1 | Antiarrythmic agents | Pfizer Limited (GB) | 1988-09-07 | — | — | EP | disclosed |
| US-4414223-A | MITICIDWS | BURROUGHS WELLCOME CO. (US) | 1983-11-08 | — | — | US | disclosed |
| US-4082770-A | ANALGESIC, ANTIPYRETIC, ANTIINFLAMMATORY | WARNER-LAMBERT COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
| US-4056526-A | ANALGESIC, ANTIPYRETIC, ANTIINFLAMMATORY | WARNER-LAMBERT COMPANY (US) | 1977-11-01 | — | — | US | disclosed |
| US-4018793-A | ANALGESICS, ANTIINFLAMMATORY, ANTIPYRETICS | WARNER-LAMBERT COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-3971814-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | WARNER-LAMBERT COMPANY (US) | 1976-07-27 | — | — | US | disclosed |