Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7628864 | 0.98 | — | — | |
| SCHEMBL3306803 | 0.86 | — | — | |
| SCHEMBL1695288 | 0.84 | ADRB2 (0.39) | — | |
| Hydrochloric Acid SCHEMBL8595507 | 0.81 | TSHR (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL28196286 | 0.79 | ADRB2 (0.36) | — | |
| SCHEMBL3307803 | 0.79 | MEN1 (0.32) | — | |
| Methyl Alcohol SCHEMBL27880650 | 0.76 | TSHR (0.34) | — | |
| Hydrochloric Acid SCHEMBL3841749 | 0.75 | MEN1 (0.37) | — | |
| SCHEMBL11504759 | 0.74 | CYP3A4 (0.40) | — | |
| SCHEMBL3308695 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833857-B1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 2002-07-24 | — | — | EP | claimed |
| US-5756588-A | CURABLE COMPOSITION COMPRISING FLUOROPOLYMER, AROMATIC POLYHYDROXY CROSSLINKING AGENT, ORGANO-ONIUM COMPOUND, MONOHYDROXYFUNCTIONAL PHENOL CAPABLE OF DELAYING POST-COMPOUNDING INITIATION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-05-26 | — | — | US | claimed |
| EP-0833857-A1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1998-04-08 | — | — | EP | claimed |
| WO-1997000906-A1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1997-01-09 | — | — | WO | claimed |
| EP-1432744-B2 | AQUEOUS EMULSION POLYMERIZATION IN THE PRESENCE OF ETHERS AS CHAIN TRANSFER AGENTS TO PRODUCE FLUOROPOLYMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2014-10-01 | — | — | EP | disclosed |
| EP-1299435-B1 | NOVEL FLUOROPOLYMER WITH IMPROVED CHARACTERISTICS, MULTILAYER ARTICLE, ELECTROSTATICALLY DISSIPATIVE ARTICLE AND METHOD | DYNEON LLC (US) | 2010-02-24 | — | — | EP | disclosed |
| EP-1383811-B1 | EMULSIFIER FREE AQUEOUS EMULSION POLYMERIZATION PROCESS FOR MAKING FLUOROPOLYMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2009-11-25 | — | — | EP | disclosed |
| EP-1392744-B1 | EMULSIFIER FREE AQUEOUS EMULSION POLYMERIZATION PROCESS FOR MAKING FLUOROPOLYMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-07-09 | — | — | EP | disclosed |
| EP-1356000-B1 | COMPOSITIONS COMPRISING FLUOROELASTOMER AND FLUOROPLASTIC | DYNEON LLC (US) | 2006-08-02 | — | — | EP | disclosed |
| US-7074862-B2 | Emulsifier free aqueous emulsion polymerization process for making fluoropolymers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-07-11 | — | — | US | disclosed |
| EP-1340773-B1 | Core-shell polymer | DYNEON LLC (US) | 2006-06-21 | — | — | EP | disclosed |
| US-20050159558-A1 | Bonding of a fluoropolymer layer to a substrate | 3M INNOVATIVE PROPERTIES COMPANY | 2005-07-21 | — | — | US | disclosed |
| WO-2002088206-A2 | EMULSIFIER FREE AQUEOUS EMULSION POLYMERIZATION PROCESS FOR MAKING FLUOROPOLYMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-11-07 | — | — | WO | disclosed |
| EP-0833857-B1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2002000777-A2 | COMPOSITIONS COMPRISING FLUOROELASTOMER AND THERMOPLASTIC FLUOROCOPOLYMER | DYNEON LLC (US) | 2002-01-03 | — | — | WO | disclosed |
| WO-2002000741-A1 | NOVEL FLUOROPOLYMERS WITH IMPROVED CHARACTERISTICS | DYNEON LLC (US) | 2002-01-03 | — | — | WO | disclosed |
| US-6310141-B1 | FLUOROELASTOMER COPOLYMERS | DYNEON LLC | 2001-10-30 | — | — | US | disclosed |
| US-5756588-A | CURABLE COMPOSITION COMPRISING FLUOROPOLYMER, AROMATIC POLYHYDROXY CROSSLINKING AGENT, ORGANO-ONIUM COMPOUND, MONOHYDROXYFUNCTIONAL PHENOL CAPABLE OF DELAYING POST-COMPOUNDING INITIATION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0833857-A1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000906-A1 | IMPROVED SCORCH SAFETY OF CURABLE FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1997-01-09 | — | — | WO | disclosed |