Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121806 | 0.82 | — | — | |
| SCHEMBL4992871 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL11237749 | 0.74 | — | — | |
| SCHEMBL7072086 | 0.73 | — | — | |
| SCHEMBL298741 | 0.70 | — | — | |
| SCHEMBL9572806 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL6277263 | 0.70 | KDM4E (0.41) | — | |
| Fluoride SCHEMBL29252244 | 0.68 | — | — | |
| SCHEMBL1193464 | 0.67 | — | — | |
| SCHEMBL4721663 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3664818-B1 | NASAL DECONGESTANT COMPOSITIONS COMPRISING MENTHOL, DEXPANTHENOL AND SODIUM HYALURONATE | ELIXIR ILAC ARASTIRMA VE GELISTIRME A S (TR) | 2023-11-29 | — | — | EP | disclosed |
| US-10906888-B2 | Pyrimidine carboxamides as inhibitors of Vanin-1 enzyme | PFIZER INC. (US) | 2021-02-02 | — | — | US | disclosed |
| US-20200246311-A1 | NASAL DECONGESTANT COMPOSITIONS COMPRISING DEXPANTHENOL AND SODIUM HYALURONATE | ELIXIR ILAC ARASTIRMA VE GELISTIRME A.S. (TR) | 2020-08-06 | — | — | US | disclosed |
| EP-3664818-A2 | NASAL DECONGESTANT COMPOSITIONS COMPRISING DEXPANTHENOL AND SODIUM HYALURONATE | Elixir Ilaç Arastirma Ve Gelistirme A.S. (TR) | 2020-06-17 | — | — | EP | disclosed |
| WO-2020102575-A1 | HETEROCYCLIC AMINOTHIAZOLES AND USES THEREOF | INCEPTION IBD, INC. (US) | 2020-05-22 | — | — | WO | disclosed |
| US-20190315715-A1 | NOVEL PYRIMIDINE CARBOXAMIDES AS INHIBITORS OF VANIN-1 ENZYME | PFIZER INC. (US) | 2019-10-17 | — | — | US | disclosed |
| US-20190292157-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS INHIBITORS OF VANIN-1 ENZYME | PFIZER INC. (US) | 2019-09-26 | — | — | US | disclosed |
| US-10308615-B2 | Heterocyclic compounds as inhibitors of Vanin-1 enzyme | PFIZER INC. (US) | 2019-06-04 | — | — | US | disclosed |
| EP-3484876-A1 | NOVEL PYRIMIDINE CARBOXAMIDES AS INHIBITORS OF VANIN-1 ENZYME | Pfizer Inc (US) | 2019-05-22 | — | — | EP | disclosed |
| US-20180148420-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS INHIBITORS OF VANIN-1 ENZYME | PFIZER INC. (US) | 2018-05-31 | — | — | US | disclosed |
| EP-2213308-A1 | Eyedrop comprising agar | TORAY INDUSTRIES INC. (JP) | 2010-08-04 | — | — | EP | disclosed |
| US-20080199524-A1 | Eyedrops containing particulate agar | TORAY INDUSTRIES, INC. (JP) | 2008-08-21 | — | — | US | disclosed |
| US-7348306-B2 | Composition for promoting lacrimal secretion | FUSO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2008-03-25 | — | — | US | disclosed |
| US-20060019904-A1 | Composition for promoting lacrimal secretion | FUSO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2006-01-26 | — | — | US | disclosed |
| US-20040266725-A1 | Polysaccharide-containing compositions and use thereof | Toray Industries., Inc. (JP) | 2004-12-30 | — | — | US | disclosed |
| EP-1424081-A1 | POLYSACCHARIDE-CONTAINING COMPOSITIONS AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 2004-06-02 | — | — | EP | disclosed |
| EP-1247532-A1 | COMPOSITION PROMOTING LACRIMAL SECRETION | FUSO PHARMACEUTICAL INDUSTRIES LTD. (JP) | 2002-10-09 | — | — | EP | disclosed |
| EP-0606486-B1 | PHARMACEUTICAL PREPARATION FOR INTRA-AIRWAY ADMINISTRATION | TEIJIN LTD (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-5626871-A | RECEPTACLES WITH CELLULOSE AND STARCH POWDERS FOR ALLERGIES, ASTHMA, BRONCHITIS OR LUNG DISEASES | TEIJIN LIMITED (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0606486-A1 | PHARMACEUTICAL PREPARATION FOR INTRA-AIRWAY ADMINISTRATION | TEIJIN LIMITED (JP) | 1994-07-20 | — | — | EP | disclosed |