Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 known ✓ | P25021 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.96 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.96 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1595766 | 1.00 | CYP1A2 (0.96) | CYP1A2CYP2D6DNM1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL2761 | 1.00 | CYP1A2 (0.96) | CYP1A2CYP2D6DNM1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL28259087 | 0.98 | CYP1A2 (0.92) | CYP1A2CYP2D6DNM1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL29244052 | 0.98 | CYP1A2 (0.92) | CYP1A2CYP2D6DNM1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL28055589 | 0.98 | CYP1A2 (0.92) | CYP1A2CYP2D6DNM1ALDH1A1TSHR | |
| Ethane SCHEMBL23167555 | 0.98 | CYP1A2 (0.92) | CYP1A2CYP2D6DNM1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL31470480 | 0.98 | CYP1A2 (0.92) | CYP1A2CYP2D6DNM1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL4449367 | 0.98 | CYP1A2 (0.92) | CYP1A2CYP2D6DNM1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL21402151 | 0.98 | CYP1A2 (0.92) | CYP1A2CYP2D6DNM1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL27646828 | 0.98 | CYP1A2 (0.92) | CYP1A2CYP2D6DNM1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118311023-A | Method for detecting novel crown antigen by near-infrared luminophor ultrasensitive full-automatic chemiluminescence method | 山东大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-118209744-A | Ultrasensitive procalcitonin antigen detection method for improving stability of luminophor based on auxiliary material method | 山东大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-116270850-B | Wuzi Yanzong oral liquid and preparation method thereof | 江西大自然制药有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-115248308-B | Application of poly-L-dopa nano-particles in preparation of immunochromatography detection test strip | 浙江大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-114965638-B | Ratio type biosensor with internal reference signal and preparation method | 南京邮电大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-114410764-B | Preparation method of long DNA sequence silica microbeads | 北京百迈客生物科技有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-117771437-A | Polyelectrolyte uniform modified intra-fiber mineralized stent material and preparation method and application thereof | 四川大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-114377210-B | Polyurethane/small intestine submucosa/polypyrrole composite material and preparation method and application thereof | 四川大学华西医院 | 2024-02-20 | — | — | CN | disclosed |
| CN-117089599-B | Long coding sequence microbead and preparation method thereof | 青岛百创智能制造技术有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117434259-A | Method for coupling magnetic beads and antibodies based on carbodiimide method | 上海思路迪生物医学科技有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-106009082-A | Coating rubber material of environment-friendly printing rubber roll and preparation method of coating rubber material | 铜陵宏正网络科技有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-106009086-A | Coating rubber material of rosin-tackified printing rubber roller and preparation method of coating rubber material | 铜陵宏正网络科技有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-106009083-A | Coating rubber material of aerogel printing rubber roll and preparation method of coating rubber material | 铜陵宏正网络科技有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-106009080-A | Coating rubber material of fireproof printing rubber roller and preparation method of coating rubber material | 铜陵宏正网络科技有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-106009079-A | Coating rubber material for composite fiber modified printing rubber roll and preparation method of coating rubber material | 铜陵宏正网络科技有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105968444-A | Coating rubber material for toughened printing rubber rolls and preparation method of coating rubber material | 铜陵宏正网络科技有限公司 | 2016-09-28 | — | — | CN | disclosed |
| US-7737166-B2 | Antifungal bicyclic hetero ring compounds | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-06-15 | — | — | US | disclosed |
| US-20090143353-A1 | such as 2-tert-Butyl-7-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-5-methyl-6-phenyl-1,3-benzoxazole-4-carbonitrile hydrochloride, a 1,6-beta-glucan synthetase inhibitor having potent growth inhibition, used treating a fungal infections; fungicides | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-06-04 | — | — | US | disclosed |
| EP-1932837-A1 | BICYCLO HETEROCYCLIC COMPOUND HAVING ANTIFUNGAL ACTION | Daiichi Sankyo Company, Limited (JP) | 2008-06-18 | — | — | EP | disclosed |
| US-RE37686-E1 | Azahydroxybenzotriazoles and derivatives thereof for peptide coupling reactions | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2002-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143353-A1 | such as 2-tert-Butyl-7-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-5-methyl-6-phenyl-1,3-benzoxazole-4-carbonitrile hydrochloride, a 1,6-beta-glucan synthetase inhibitor having potent growth inhibition, used treating a fungal infections; fungicides | CTPS1, TPP1, STS | HRH2 4005/4885CYP1A2 605/4885CYP2D6 1064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.