Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.35 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.35 |
| ▸ | HDAC1 known ✓ | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 known ✓ | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC6 known ✓ | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.34 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.34 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.33 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6116105 | 0.97 | — | — | |
| SCHEMBL44143 | 0.97 | — | — | |
| SCHEMBL28278850 | 0.95 | TDP1 (0.36) | KDM4ELMNATDP1DGAT1MAOA | |
| Ammonia Solution, Strong SCHEMBL20241550 | 0.95 | TDP1 (0.36) | KDM4ELMNATDP1DGAT1MAOA | |
| Acetic Acid SCHEMBL23783571 | 0.93 | KDM4E (0.37) | KDM4ELMNATDP1DGAT1MAOA | |
| Ethylamine SCHEMBL7474222 | 0.92 | TDP1 (0.35) | KDM4ELMNATDP1DGAT1MAOA | |
| Hydrochloric Acid SCHEMBL14659623 | 0.92 | TDP1 (0.35) | KDM4ELMNATDP1DGAT1MAOA | |
| Bicarbonate SCHEMBL28222758 | 0.91 | KDM4E (0.33) | KDM4ELMNATDP1DGAT1MAOA | |
| Acetic Acid SCHEMBL4576890 | 0.90 | GLRA1 (0.35) | KDM4ETDP1DGAT1MAOAMAOB | |
| SCHEMBL9725893 | 0.90 | TDP1 (0.34) | KDM4ELMNATDP1DGAT1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2032 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528812-B | Double amino acid-genipin derivative and preparation method and application thereof | 广东工业大学 | 2025-06-03 | — | — | CN | claimed |
| CN-116836188-B | Probe prodrug and probe for detecting OX-LDL and application of probe for detecting vascular atherosclerosis | 南京大学 | 2025-05-06 | — | — | CN | claimed |
| CN-115521328-B | Organic boron fluorescent material and preparation method and application thereof | 河南农业大学 | 2025-03-21 | — | — | CN | claimed |
| CN-119528812-A | Double amino acid-genipin derivative and preparation method and application thereof | 广东工业大学 | 2025-02-28 | — | — | CN | claimed |
| CN-119241644-A | Synthesis method of linker MC-Gly-Gly-Phe-Gly-OH | 瑞博(苏州)制药有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-118271251-A | Intermediate compound, preparation method thereof and method for preparing dapest | 武汉工程大学 | 2024-07-02 | — | — | CN | claimed |
| CN-118255796-A | Tool molecule for exploring targeting property of BPA boron-like drug in tumor tissue and method for detecting distribution of BPA boron-like drug in tumor tissue | 兰州大学 | 2024-06-28 | — | — | CN | claimed |
| CN-115475164-B | Protein degradation targeting chimeric capable of degrading PDGFR-beta, preparation method and application thereof | 西安交通大学 | 2024-06-04 | — | — | CN | claimed |
| CN-117720617-A | Synthesis process of acetyl tetrapeptide-3 | 山东济肽生物科技有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-113912524-B | Polypeptide compound containing sulfur amide and synthesis method thereof | 华东师范大学 | 2023-12-01 | — | — | CN | claimed |
| CN-103946218-B | Suppress stable crystal form and the application thereof of the compound of Protocollagen prolyl hydroxylase activity | ZHEJIANG BETA PHARMA INC. (CN) | 2016-03-09 | — | — | CN | claimed |
| CN-105037489-A | Glyoxalase I irreversible inhibitor, preparation method and application thereof | UNIV CHENGDU | 2015-11-11 | — | — | CN | claimed |
| CN-105037490-A | Glyoxalase I irreversible inhibitor, preparation method and application thereof | UNIV CHENGDU | 2015-11-11 | — | — | CN | claimed |
| US-20140343137-A1 | Stable Polymorphic Forms of Compound as Hypoxia Mimetics, and Uses Thereof | BEIJING BETTA PHARMACEUTICALS CO., LTD. (CN) | 2014-11-20 | — | — | US | claimed |
| CN-103946218-A | Stable polymorphic forms of compound as hypoxia mimetics, and uses thereof | BEIJING BETA PHARMA INC | 2014-07-23 | — | — | CN | claimed |
| EP-2736892-A1 | STABLE POLYMORPHIC FORMS OF COMPOUND AS HYPOXIA MIMETICS, AND USES THEREOF | Beijing Betta Pharmaceuticals Co., Ltd (CN) | 2014-06-04 | — | — | EP | claimed |
| CN-103214383-A | Process for synthesis of tert-butyl glycinate and further synthesis of N-protected tert-butyl glycinate | SICHUAN TONGSHENG AMINO ACID CO LTD | 2013-07-24 | — | — | CN | claimed |
| WO-2013017063-A1 | STABLE POLYMORPHIC FORMS OF COMPOUND AS HYPOXIA MIMETICS, AND USES THEREOF | ZHEJIANG BETA PHARMA INCORPORATION (CN) | 2013-02-07 | — | — | WO | claimed |
| US-6455698-B1 | FOR TREATING CEREBRAL ISCHEMIA OR CEREBRAL INFARCTION RESULTING FROM THROMBOEMBOLIC OR HEMORRHAGIC STROKE, CEREBRAL VASOSPASMS, HYPOGLYCEMIA, CARDIAC ARREST, NEURODEGENERATIVE DISORDERS | WARNER-LAMBERT COMPANY | 2002-09-24 | — | — | US | claimed |
| US-20020065415-A1 | Conformationally semi-constrained quinoxaline 2,3-diones as neuroprotective agents | KORNBERG BRIAN EDWARD (US) | 2002-05-30 | — | — | US | claimed |