Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | CDC25B | P30305 | 2/20 | 0.73 |
| ▸ | CDC25A | P30304 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL893971 | 1.00 | POLB (0.77) | POLBTDP1L3MBTL1CDC25BCDC25A | |
| SCHEMBL48886 | 0.98 | POLB (0.80) | POLBTDP1L3MBTL1CDC25BCDC25A | |
| SCHEMBL29404709 | 0.98 | POLB (0.80) | POLBTDP1L3MBTL1CDC25BCDC25A | |
| SCHEMBL30754379 | 0.95 | TDP1 (0.84) | POLBTDP1L3MBTL1CDC25BCDC25A | |
| SCHEMBL6693862 | 0.95 | POLB (0.77) | POLBTDP1L3MBTL1CDC25BCDC25A | |
| SCHEMBL203260 | 0.95 | TDP1 (0.84) | POLBTDP1L3MBTL1CDC25BCDC25A | |
| SCHEMBL268918 | 0.95 | POLB (0.77) | POLBTDP1L3MBTL1CDC25BCDC25A | |
| SCHEMBL7045921 | 0.95 | TDP1 (0.84) | POLBTDP1L3MBTL1CDC25BCDC25A | |
| SCHEMBL29440676 | 0.95 | TDP1 (0.84) | POLBTDP1L3MBTL1CDC25BCDC25A | |
| SCHEMBL6866245 | 0.91 | POLB (0.78) | POLBTDP1L3MBTL1CDC25BCDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649194-B1 | THERMOPLASTIC RESIN COMPOSITION WITH IMPROVED UV RESISTANCE | INEOS STYROLUTION GROUP GMBH (DE) | 2024-06-12 | — | — | EP | disclosed |
| EP-4153682-B1 | FLAME-RETARDANT POLYCARBONATE COMPOSITION | COVESTRO DEUTSCHLAND AG (DE) | 2024-06-05 | — | — | EP | disclosed |
| EP-4153681-B1 | FLAME-RETARDANT POLYCARBONATE COMPOSITION | COVESTRO DEUTSCHLAND AG (DE) | 2024-05-29 | — | — | EP | disclosed |
| US-11965066-B2 | Thermoplastic compositions with improved UV resistance | INEOS STYROLUTION GROUP GMBH (DE) | 2024-04-23 | — | — | US | disclosed |
| US-20240117171-A1 | BLACK STYRENE COPOLYMER COMPOSITIONS FOR HIGH GLOSS EXTERIOR APPLICATIONS | INEOS STYROLUTION GROUP GMBH (DE) | 2024-04-11 | — | — | US | disclosed |
| US-20240093018-A1 | STYRENE COPOLYMER MOLDING COMPOSITIONS WITH REDUCED MOLD DEPOSIT FORMATION FOR HIGH GLOSS APPLICATIONS | INEOS STYROLUTION GROUP GMBH (DE) | 2024-03-21 | — | — | US | disclosed |
| US-20240026146-A1 | WEATHERING-RESISTANT STYRENE COPOLYMER MOLDING COMPOSITIONS WITH REDUCED MOLD DEPOSIT FORMATION FOR HIGH GLOSS APPLICATIONS | INEOS STYROLUTION GROUP GMBH (DE) | 2024-01-25 | — | — | US | disclosed |
| US-11708455-B2 | Flame-retardant polycarbonate composition | COVESTRO DEUTSCHLAND AG (DE) | 2023-07-25 | — | — | US | disclosed |
| US-20230212389-A1 | FLAME-RETARDANT POLYCARBONATE COMPOSITION | COVESTRO DEUTSCHLAND AG (DE) | 2023-07-06 | — | — | US | disclosed |
| EP-4045362-B1 | BLACK STYRENE COPOLYMER COMPOSITIONS FOR HIGH GLOSS EXTERIOR APPLICATIONS | INEOS STYROLUTION GROUP GMBH (DE) | 2023-07-05 | — | — | EP | disclosed |
| US-20020160177-A1 | Polycarbonate compositions with improved foam adhesion | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-31 | — | — | US | disclosed |
| US-20020147256-A1 | Flame-resistant polycarbonate compositions | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-10 | — | — | US | disclosed |
| US-20020115761-A1 | Polycarbonate compositions | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-22 | — | — | US | disclosed |
| US-6433082-B1 | POLYCARBONATE MOLDING COMPOSITIONS BLENDED WITH ELASTIC GRAFT POLYMERS AND POLYPHOSPHAZENES; FIREPROOF, IMPACT RESISTANCE, AND EXCELLENT SOFTENING TEMPERATURE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-13 | — | — | US | disclosed |
| US-5164474-A | Molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-17 | — | — | US | disclosed |
| US-4719279-A | POLYESTERS, POLYCARBONATES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-01-12 | — | — | US | disclosed |
| US-4714746-A | Process for the preparation of aromatic polyester-carbonates having improved notched impact strength, and polyester-carbonates prepared thereby and their use for the production of mouldings, films and coatings | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-22 | — | — | US | disclosed |
| US-4704430-A | BLENDS OF POLYCARBONATES, POLYESTERS AND BLOCK POLYCARBONATE ETHER COPOLYMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-11-03 | — | — | US | disclosed |
| US-4366276-A | Flame-resistant moulding materials based on thermoplastic aromatic polyesters and polyesters carbonates, a process for their production and their use in the production of moulded bodies | BAYER AKTIENGESELLSCHAFT (DE) | 1982-12-28 | — | — | US | disclosed |
| US-4334053-A | CHAIN TERMINATED BY ALKYL-SUBSTITUTED PHENOL, PHENYL HALOGORMATES OR PHENYLACYL CHLORIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |