Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.32 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22186 | 0.97 | — | — | |
| SCHEMBL21992235 | 0.97 | — | — | |
| Hydrazine SCHEMBL28176811 | 0.94 | ALDH1A1 (0.35) | ALDH1A1DNM1LMNANFKB1GABBR2 | |
| Ethylenediamine SCHEMBL5184739 | 0.94 | ALDH1A1 (0.35) | ALDH1A1DNM1LMNANFKB1GABBR2 | |
| SCHEMBL28076709 | 0.94 | ALDH1A1 (0.35) | ALDH1A1DNM1LMNANFKB1GABBR2 | |
| SCHEMBL3965273 | 0.94 | — | — | |
| Methane SCHEMBL28919278 | 0.94 | — | — | |
| SCHEMBL6261863 | 0.94 | ALDH1A1 (0.35) | ALDH1A1DNM1LMNANFKB1GABBR2 | |
| Ammonia Solution, Strong SCHEMBL3124611 | 0.94 | ALDH1A1 (0.35) | ALDH1A1DNM1LMNANFKB1GABBR2 | |
| Ammonia Solution, Strong SCHEMBL8642115 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11261402-B2 | Treatment compositions | THE PROCTER & GAMBLE COMPANY (US) | 2022-03-01 | — | — | US | disclosed |
| US-10689600-B2 | Treatment compositions | THE PROCTER & GAMBLE COMPANY (US) | 2020-06-23 | — | — | US | disclosed |
| EP-3408365-A1 | TREATMENT COMPOSITIONS | The Procter and Gamble Company (US) | 2018-12-05 | — | — | EP | disclosed |
| EP-3408364-A1 | TREATMENT COMPOSITIONS | The Procter and Gamble Company (US) | 2018-12-05 | — | — | EP | disclosed |
| WO-2017132099-A1 | TREATMENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2017-08-03 | — | — | WO | disclosed |
| WO-2017132100-A1 | TREATMENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2017-08-03 | — | — | WO | disclosed |
| US-20170211017-A1 | TREATMENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY | 2017-07-27 | — | — | US | disclosed |
| US-20170211018-A1 | TREATMENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY | 2017-07-27 | — | — | US | disclosed |
| EP-1100857-B1 | USE OF SURFACE ACTIVE AGENTS TO REDUCE SCUM IN FABRIC CARE COMPOSITIONS | PROCTER & GAMBLE (US) | 2010-11-03 | — | — | EP | disclosed |
| US-20100150975-A1 | Structured Composition Comprising an Encapsulated Active | THE PROCTER & GAMBLE COMPANY | 2010-06-17 | — | — | US | disclosed |
| US-5445747-A | Containing fabric softener, perfume selected to cover odors | THE PROCTER & GAMBLE COMPANY (US) | 1995-08-29 | — | — | US | disclosed |
| EP-0665877-A1 | FABRIC SOFTENERS CONTAINING DYES FOR REDUCED STAINING | THE PROCTER & GAMBLE COMPANY (US) | 1995-08-09 | — | — | EP | disclosed |
| EP-0640121-A1 | CONCENTRATED FABRIC SOFTENER COMPOSITIONS CONTAINING BIODEGRADABLE FABRIC SOFTENERS | THE PROCTER & GAMBLE COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |
| WO-1995005442-A1 | CELLULASE FABRIC-CONDITIONING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1995-02-23 | — | — | WO | disclosed |
| WO-1995005443-A1 | FABRIC-CONDITIONING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1995-02-23 | — | — | WO | disclosed |
| WO-1994020597-A1 | CONCENTRATED BIODEGRADABLE QUATERNARY AMMONIUM FABRIC SOFTENER COMPOSITIONS AND COMPOUNDS CONTAINING INTERMEDIATE IODINE VALUE UNSATURATED FATTY ACID CHAINS | THE PROCTER & GAMBLE COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |
| WO-1994010285-A1 | FABRIC SOFTENERS CONTAINING DYES FOR REDUCED STAINING | THE PROCTER & GAMBLE COMPANY (US) | 1994-05-11 | — | — | WO | disclosed |
| WO-1994007979-A1 | METHOD FOR USING SOLID PARTICULATE FABRIC SOFTENER IN AUTOMATIC DOSING DISPENSER | THE PROCTER & GAMBLE COMPANY (US) | 1994-04-14 | — | — | WO | disclosed |
| WO-1993023510-A1 | CONCENTRATED FABRIC SOFTENER COMPOSITIONS CONTAINING BIODEGRADABLE FABRIC SOFTENERS | THE PROCTER & GAMBLE COMPANY (US) | 1993-11-25 | — | — | WO | disclosed |
| US-5183704-A | Flocculating aqueous dispersion of chemically delaminated mica or vermiculite; removing water while preserving lamellar structure; heat insulation | ARMSTRONG WORLD INDUSTRIES, INC. (US) | 1993-02-02 | — | — | US | disclosed |