Hydrochloric Acid

Hydrochloric Acid

SCHEMBL360708

Cl.Nc1ncncn1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8681532 1.00
SCHEMBL4458 0.96
SCHEMBL27469274 0.93 HSP90AA1 (0.93)
SCHEMBL28210447 0.93
SCHEMBL854885 0.93
Water SCHEMBL4239659 0.93 HSP90AA1 (0.93)
Water SCHEMBL6705186 0.93
Formaldehyde SCHEMBL3745731 0.87
Boric Acid SCHEMBL8843854 0.84 HSP90AA1 (0.77)
SCHEMBL578041 0.84 HSP90AA1 (0.77)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101760962-A Modification method of cellulose fiber fabric and salt-free dyeing method UNIV DONGHUA 2010-06-30 CN claimed
CN-118955685-A Pymetrozine artificial antigen and preparation method and application thereof 泰州市食品检验院 2024-11-15 CN disclosed
CN-118459712-A Heat-resistant toughened polyurethane resin and preparation method thereof 深圳市深赛尔股份有限公司 2024-08-09 CN disclosed
CN-118459712-A Heat-resistant toughened polyurethane resin and preparation method thereof 深圳市深赛尔股份有限公司 2024-08-09 CN disclosed
CN-115087643-B Condensed heterocyclic compound, preparation method and medical application thereof 中国医药研究开发中心有限公司 2023-10-27 CN disclosed
CN-116535515-A Monoclonal antibody for resisting pymetrozine and application thereof 武汉上成生物科技有限公司 2023-08-04 CN disclosed
WO-2022152138-A1 CONDENSED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF 中国医药研究开发中心有限公司 2022-07-21 WO disclosed
CN-113767100-A Bicyclic heteroaryl compounds and uses thereof 锐新医药公司 2021-12-07 CN disclosed
EP-2418190-B1 The method of preparation of enantiomerically enriched products of condensation from racemic acids or acids of the low enentiomeric purity POLITECHNIKA LODZKA (PL) 2013-08-28 EP disclosed
EP-2407460-B1 N-TRIAZINYLAMMONIUM SALTS, A METHOD OF PREPARATION AND USES THEREOF POLITECHNIKA LODZKA (PL) 2013-07-17 EP disclosed
EP-2418190-A1 The method of preparation of enantiomerically enriched products of condensation from racemic acids or acids of the low enentiomeric purity Politechnika Lodzka (PL) 2012-02-15 EP disclosed
EP-2407460-A1 N-Triazinylammonium salts, a method of preparation and uses thereof Politechnika Lódzka (PL) 2012-01-18 EP disclosed
US-20100292469-A1 PROCESS FOR THE PREPARATION OF N-TRIAZINYLAMMONIUM SALTS ITALVELLUTI S.P.A. (IT) 2010-11-18 US disclosed
CN-101760962-A Modification method of cellulose fiber fabric and salt-free dyeing method UNIV DONGHUA 2010-06-30 CN disclosed
EP-1586566-B9 P-toluenosulfonate salt of N-Methyl-N-(3,5-dimathoxy-2,4,6-triazinyl-1-)-morpholine and related compounds for use as condensing reagent in peptide synthesis POLITECHNIKA LODZKA (PL) 2009-11-18 EP disclosed
CN-101509191-A Multi-active base full-substituted triazine cation graft agents, preparation and use method thereof UNIV DONGHUA (CN) 2009-08-19 CN disclosed
EP-1586566-B1 P-toluenosulfonate salt of N-Methyl-N-(3,5-dimathoxy-2,4,6-triazinyl-1-)-morpholine and related compounds for use as condensing reagent in peptide synthesis POLITECHNIKA LODZKA (PL) 2009-05-13 EP disclosed
EP-1951691-A1 PROCESS FOR THE PREPARATION OF N-TRIAZINYLAMMONIUM SALTS Italvelluti S.p.A. (IT) 2008-08-06 EP disclosed
WO-2007051496-A1 PROCESS FOR THE PREPARATION OF N-TRIAZINYLAMMONIUM SALTS ITALVELLUTI S.P.A. (IT) 2007-05-10 WO disclosed
EP-1586566-A1 P-toluenosulfonate salt of N-Methyl-N-(3,5-dimathoxy-2,4,6-triazinyl-1-)-morpholine and related compounds for use as condensing reagent in peptide synthesis Politechnika Lodzka (PL) 2005-10-19 EP disclosed