Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.33 |
| ▸ | PTGS2 known ✓ | P35354 | 3/20 | 0.32 |
| ▸ | ESR1 known ✓ | P03372 | 2/20 | 0.32 |
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.32 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.32 |
| ▸ | KCNH2 known ✓ | Q12809 | 2/20 | 0.32 |
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.32 |
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.32 |
| ▸ | EGFR known ✓ | P00533 | 1/20 | 0.32 |
| ▸ | LCK known ✓ | P06239 | 1/20 | 0.32 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.32 |
| ▸ | MAPK14 known ✓ | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL616916 | 1.00 | ACHE (0.33) | ACHEBACE1PTGS2ESR1ADRA2A | |
| Hydrochloric Acid SCHEMBL7082368 | 1.00 | ACHE (0.33) | ACHEBACE1PTGS2ESR1ADRA2A | |
| Hydrochloric Acid SCHEMBL1685599 | 1.00 | ACHE (0.33) | ACHEBACE1PTGS2ESR1ADRA2A | |
| Hydrochloric Acid SCHEMBL5359567 | 1.00 | ACHE (0.33) | ACHEBACE1PTGS2ESR1ADRA2A | |
| Hydrochloric Acid SCHEMBL21854564 | 1.00 | ACHE (0.33) | ACHEBACE1PTGS2ESR1ADRA2A | |
| Hydrochloric Acid SCHEMBL3682820 | 0.98 | ACHE (0.30) | ACHEBACE1 | |
| SCHEMBL27485462 | 0.98 | ACHE (0.33) | ACHEBACE1PTGS2ESR1ADRA2A | |
| SCHEMBL821696 | 0.98 | ACHE (0.33) | ACHEBACE1PTGS2ESR1ADRA2A | |
| SCHEMBL8147082 | 0.98 | ACHE (0.33) | ACHEBACE1PTGS2ESR1ADRA2A | |
| SCHEMBL822442 | 0.98 | ACHE (0.33) | ACHEBACE1PTGS2ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517928-B1 | SUPPORTED HYBRID METALLOCENE CATALYST, METHOD FOR PREPARING THE SAME, AND METHOD FOR PREPARING POLYOLEFIN USING THE SAME | LG CHEMICAL LTD (KR) | 2010-11-10 | — | — | EP | disclosed |
| US-7294600-B2 | Supported hybrid metallocene catalyst, method for preparing the same, and method for preparing polyolefin using the same | LG CHEM, LTD. (KR) | 2007-11-13 | — | — | US | disclosed |
| US-7247595-B2 | Supported metallocene catalyst and olefin polymerization using the same | LG CHEM, LTD. (KR) | 2007-07-24 | — | — | US | disclosed |
| EP-1016689-B1 | Olefin thermoplastic elastomer compositions | MITSUI CHEMICALS INC (JP) | 2007-03-07 | — | — | EP | disclosed |
| US-20060235171-A1 | Supported hybrid metallocene catalyst, method for preparing the same, and method for preparing polyolefin using the same | LG CHEM, LTD. (KR) | 2006-10-19 | — | — | US | disclosed |
| US-20060135351-A1 | Supported metallocene catalyst and olefin polymerization using the same | LG CHEM, LTD. (KR) | 2006-06-22 | — | — | US | disclosed |
| US-7041618-B2 | Supported metallocene catalyst and olefin polymerization using the same | LG CHEMICAL LTD. (KR) | 2006-05-09 | — | — | US | disclosed |
| EP-1390374-B1 | SUPPORTED POLYMERIZATION CATALYST USING A CATALYST PRECUSOR HAVING FUNCTIONAL GROUP AND SURFACE MODIFIED CARRIER AND OLEFIN POLYMERIZATION USING THE SAME | LG CHEMICAL LTD (KR) | 2006-03-01 | — | — | EP | disclosed |
| US-6908877-B2 | Supported polymerization catalyst using a catalyst precursor having functional group and surface modified carrier and olefin polymerization using the same | LG CHEM. LTD. (KR) | 2005-06-21 | — | — | US | disclosed |
| EP-1057867-B1 | RESIN DISPERSION, METHOD OF PREPARING THE SAME, RESIN-COATED METAL SHEET OBTAINED WITH THE SAME, AND PROCESS FOR PRODUCING LAMINATE | MITSUI CHEMICALS INC (JP) | 2005-04-20 | — | — | EP | disclosed |
| EP-0751182-A1 | Olefin thermoplastic elastomer compositions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5567777-A | CONTAINING AN ALPHA-OLEFIN; TRANSPARENCY | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-22 | — | — | US | disclosed |
| US-5567776-A | BLEND ELASTOMERIC COPOLYMERS CONTAINING ALPHA- AND CYCLO-OLEFINS; IMPACT STRENGTH, TRANSPARENCY, FIBER OPTICS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-22 | — | — | US | disclosed |
| EP-0691354-A1 | Unsaturated copolymer of ethylene and process for preparing the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-10 | — | — | EP | disclosed |
| US-5470919-A | Seals with ozone resistance, heat aging resistance, oil resistance and weatherproofing | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0638594-A1 | Chlorinated ethylene/alpha-olefin copolymer rubber and composition containing the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| EP-0597119-A1 | CYCLOOLEFIN COPOLYMER COMPOSITION AND PRODUCTION THEREOF | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |
| EP-0303519-B1 | POLYMERIZATION OF ETHYLENE | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-4931517-A | Polymerization of ethylene | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1990-06-05 | — | — | US | disclosed |
| EP-0303519-A1 | Polymerization of ethylene | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135351-A1 | Supported metallocene catalyst and olefin polymerization using the same | MCM4, OSBP, POF1B | ACHE 832/4885PTGS2 1139/4885ESR1 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.