Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 known ✓ | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 known ✓ | P32297 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301263 | 0.73 | — | — | |
| SCHEMBL1473425 | 0.66 | — | — | |
| SCHEMBL2544000 | 0.64 | — | — | |
| SCHEMBL28034222 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL6744745 | 0.62 | TDP1 (0.63) | TDP1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL23298138 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL27685609 | 0.62 | — | — | |
| SCHEMBL10605531 | 0.62 | — | — | |
| SCHEMBL21929526 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL22346327 | 0.62 | CHRNB2 (0.37) | TDP1CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3474678-A1 | HYDROXY METHIONINE ANALOG FORMULATIONS SUITABLE FOR SPECIALTY CHEMICAL APPLICATIONS | Novus International Inc. (US) | 2019-05-01 | — | — | EP | disclosed |
| EP-3374428-A1 | SULFUR-CONTAINING COMPOUNDS AS SOLVENTS | Novus International Inc. (US) | 2018-09-19 | — | — | EP | disclosed |
| WO-2018151884-A1 | SEED FLOW LUBRICANT COMPOSITIONS AND USES THEREOF | 3 Star Ag LLC (US) | 2018-08-23 | — | — | WO | disclosed |
| WO-2017223172-A1 | HYDROXY METHIONINE ANALOG FORMULATIONS SUITABLE FOR SPECIALTY CHEMICAL APPLICATIONS | NOVUS INTERNATIONAL INC. (US) | 2017-12-28 | — | — | WO | disclosed |
| WO-2017083518-A1 | SULFUR-CONTAINING COMPOUNDS AS SOLVENTS | NOVUS INTERNATIONAL INC. (US) | 2017-05-18 | — | — | WO | disclosed |
| WO-2010126794-A1 | METHODS FOR INCREASING GROWTH AND YIELD OF PLANTS WITH METHIONINE COMPOUNDS | NOVUS INTERNATIONAL INC. (US) | 2010-11-04 | — | — | WO | disclosed |
| WO-2009135049-A1 | METHODS AND COMPOSITIONS OF PLANT MICRONUTRIENTS | NOVUS INTERNATIONAL INC. (US) | 2009-11-05 | — | — | WO | disclosed |
| EP-2106257-A2 | COMPOSITIONS FOR PROVIDING COLOR TO ANIMATE OBJECTS AND RELATED METHODS | PPG Industries Ohio, Inc. (US) | 2009-10-07 | — | — | EP | disclosed |
| WO-2008091916-A2 | COMPOSITIONS FOR PROVIDING COLOR TO ANIMATE OBJECTS AND RELATED METHODS | PPG INDUSTRIES OHIO, INC. (US) | 2008-07-31 | — | — | WO | disclosed |
| EP-1170997-A1 | MICROENCAPSULATED SOLID PESTICIDES | Syngenta Participations AG (CH) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000062612-A1 | MICROENCAPSULATED SOLID PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-10-26 | — | — | WO | disclosed |
| EP-0999744-A1 | EFFECT ENHANCER FOR AGRICULTURAL CHEMICAL | Kao Corporation (JP) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999003345-A1 | EFFECT ENHANCER FOR AGRICULTURAL CHEMICAL | KAO CORPORATION (JP) | 1999-01-28 | — | — | WO | disclosed |