Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Docusate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.44 |
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.92 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Docusate SCHEMBL8080919 | 1.00 | RECQL (0.92) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL9229113 | 0.99 | RECQL (0.94) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL5987875 | 0.99 | RECQL (0.94) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL10998529 | 0.99 | RECQL (0.94) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL10454277 | 0.97 | RECQL (0.92) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL1395966 | 0.97 | RECQL (0.92) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL6247110 | 0.97 | RECQL (0.92) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL2384327 | 0.97 | RECQL (0.92) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL3794005 | 0.97 | RECQL (0.92) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL8979655 | 0.97 | RECQL (0.92) | RECQLCYP3A4TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775922-A | Preparation method of corrosion-resistant photovoltaic packaging material | 江苏固尚新能源有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-119661844-A | Low-density polyimide foam material and preparation method thereof | 贵州航天天马机电科技有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-113710718-B | Stabilized silane-modified polymer compositions and methods | 迈图高新材料公司 | 2024-06-25 | — | — | CN | claimed |
| CN-117960093-A | Preparation method and reaction device of alkyl tin oxide | 恒光新材料(江苏)股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117700445-A | Preparation method of dioctyl tin oxide | 广东先导微电子科技有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-113092617-B | Novel method for rapidly and simultaneously determining components in octyl tin chloride solution | 云南锡业研究院有限公司 | 2023-03-03 | — | — | CN | claimed |
| CN-113092617-A | Novel method for rapidly and simultaneously determining components in octyl tin chloride solution | 云南锡业研究院有限公司 | 2021-07-09 | — | — | CN | claimed |
| CN-103313996-A | Process for preparing monoalkyltin trihalides and dialkyltin dihalides | PMC ORGANOMETALLIX INC | 2013-09-18 | — | — | CN | claimed |
| CN-101679624-B | Process for preparing hydrolyzable silylated polymers | MOMENTIVE PERFORMANCE MAT INC | 2012-07-04 | — | — | CN | claimed |
| CN-101679624-A | Process for preparing hydrolyzable silylated polymers | MOMENTIVE PERFORMANCE MAT INC | 2010-03-24 | — | — | CN | claimed |
| US-6787661-B2 | USED AS ANIONIC POLYMERIZATION INITIATORS FOR HOMO OR COPOLYMERIZATION OF CONJUGATED DIENE AND AROMATIC VINYL MONOMERS | CHINA PETROLEUM AND CHEMICAL CORPORATION (CN) | 2004-09-07 | — | — | US | claimed |
| US-20030181747-A1 | Tin-containing organolithium compounds and preparation thereof | CHINA PETROLEUM AND CHEMICAL CORP AND RESEARCH INSTITUTE OF BEIJING YANSHAN PETROCHEMICAL CO LTD | 2003-09-25 | — | — | US | claimed |
| CN-1035942-C | Process for producing higher cyanoacetic ester | NITTO CHEMICAL INDUSTRY CO LTD (JP) | 1997-09-24 | — | — | CN | claimed |
| CN-1118162-A | Process for producing higher cyanoacetic ester | NITTO CHEMICAL INDUSTRY CO LTD (JP) | 1996-03-06 | — | — | CN | claimed |
| JP-5212969-A | — | — | None | — | — | JP | disclosed |
| CN-120005493-A | Exposed polyurea coating and preparation method thereof | 石家庄修神化工产品有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-119775922-A | Preparation method of corrosion-resistant photovoltaic packaging material | 江苏固尚新能源有限公司 | 2025-04-08 | — | — | CN | disclosed |
| US-4153723-A | ANILINOMETHYLENEMALONONITRILES | CIBA-GEIGY CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |
| US-4151298-A | ANILINOMETHYLENEMALONONITRILE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1979-04-24 | — | — | US | disclosed |
| US-4066397-A | CURING POLYETHER-URETHANE | MILLIKEN RESEARCH CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181747-A1 | Tin-containing organolithium compounds and preparation thereof | MLX, CDY1; CDY1B, TELO2 | CA2 3101/4885MMP8 4799/4885RECQL 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.